Lucas Zier, MD

Education
M.D., 2009 - Medicine, University of California, San Francisco
M.S., 2007 - Medicine, University of California, San Francisco
Websites
Publications

  1. Jonathan D. Davis, Daniel Bennett, Avni Kothari, Jean Feng, Lucas S. Zier. A CUSTOM POINT OF CARE, DIGITALLY INTEGRATED, DECISION SUPPORT TOOL INCREASES GUIDELINE-DIRECTED HEART FAILURE MEDICATION UTILIZATION IN A SAFETY-NET SYSTEM. Journal of the American College of Cardiology 2025. PMID:


  2. Colette DeJong, Matthew Durstenfeld, Jonathan D. Davis, Christina Wang, Marta Levkova, Veronica Schaffer, Elise Riley, Mark D. Huffman, Matt Hickey, Starley Shade, Justin C. Chen, Wayne Steward, Dhruv Kazi, Janet Grochowski, Lucas S. Zier, Niloufar Moreau, Alex Sandhu, Paul A. Heidenreich, Anubha Agarwal, Priscilla Y. Hsue. EARLY RESULTS OF THE COMBO-HF-X PILOT CROSSOVER TRIAL: DELIVERING QUADRUPLE THERAPY FOR HEART FAILURE WITH REDUCED EJECTION FRACTION IN A SINGLE CAPSULE IN A SAFETY NET HEALTHCARE SYSTEM. Journal of the American College of Cardiology 2025. PMID:


  3. DeJong C, Durstenfeld MS, Davis JD, Wang CS, Riley ED, Huffman MD, Hickey MD, Shade SB, Chen JC, Kazi DS, Grochowski J, Steward WT, Zier LS, Moreau N, Sandhu AT, Heidenreich PA, Agarwal A, Hsue PY. Delivering guideline-directed medical therapy for heart failure with reduced ejection fraction as an over-encapsulated polypill: rationale and protocol for the COMBO-HF-X pilot crossover randomised clinical trial. BMJ open 2025. PMID: 40118491


  4. DeJong C, Durstenfeld MS, Davis J, Wang CS, Chen J, Kazi DS, Hickey MD, Grochowski J, Steward WT, Riley ED, Zier LS, Moreau N, Huffman MD, Sandhu AT, Heidenreich PA, Agarwal A, Hsue PY. Prototyping and Manufacturing of Customized Over-Encapsulated Polypills for Heart Failure with Reduced Ejection Fraction in a Safety-Net Healthcare System. Journal of cardiac failure 2025. PMID: 40169092


  5. Bennett DJ, Feng J, Goldman S, Kothari A, Gottlieb LM, Durstenfeld MS, Marks J, Ehrlich S, Davis J, Zier LS. Reducing readmissions in the safety net through AI and automation. The American journal of managed care 2025. PMID: 40053406


  6. Durstenfeld MS, Thakkar A, Ma Y, Zier LS, Davis JD, Hsue PY. Association Between Coronary Assessment in Heart Failure and Clinical Outcomes Within a Safety-Net Setting Using a Target Trial Emulation Observational Design. Circulation. Cardiovascular quality and outcomes 2024. PMID: 38682336


  7. Steverson AB, Marano PJ, Chen C, Ma Y, Stern RJ, Feng J, Gennatas ED, Marks JD, Durstenfeld MS, Davis JD, Hsue PY, Zier LS. Predictors of All-Cause 30-Day Readmissions in Patients with Heart Failure at an Urban Safety Net Hospital: The Importance of Social Determinants of Health and Mental Health. American Journal of Medicine Open 2023. PMID: 39035237


  8. Durstenfeld MS, Thakkar A, Ma Y, Zier LS, Davis JD, Hsue PY. Coronary Assessment in Heart Failure within a Safety-Net Setting: Disparities and Outcomes. medRxiv : the preprint server for health sciences 2023. PMID: 37461492


  9. DesJardin JT, Svetlichnaya Y, Kolaitis NA, Hays SR, Kukreja J, Schiller NB, Zier LS, Singer JP, De Marco T. Echocardiographic estimation of pulmonary vascular resistance in advanced lung disease. Pulmonary circulation 2023. PMID: 36618711


  10. Xia VQ, Ong CM, Zier LS, MacGregor JS, Wu AHB, Chorba JS. Heparin Does Not Regulate Circulating Human PCSK9 (Proprotein Convertase Subtilisin-Kexin Type 9) in a General Population. Arteriosclerosis, thrombosis, and vascular biology 2022. PMID: 36475702


  11. Matthew S Durstenfeld, Anjali Thakkar, Yifei Ma, Lucas Zier, Jonathan D Davis, Priscilla Hsue. Abstract 11069: Evaluation for Ischemic Cardiomyopathy After Heart Failure Diagnosis is Associated With Reduced Mortality in a Safety-Net Setting. Circulation 2022. PMID:


  12. Marano PJ, Steverson AB, Chen C, Ma Y, Stern RJ, Davis J, Hsue PY, Zier LS. Effect of a Novel, Evidence-Based, Standardized Discharge Checklist on 30-Day All-Cause Readmissions in Patients Hospitalized for Heart Failure in an Urban Safety Net Hospital. The American journal of cardiology 2022. PMID: 36028389


  13. Ganeshan S, Kelemen B, Dhaliwal G, Zier L. An unexpected turn: A 71-year-old man with myocardial infarction. Cleveland Clinic journal of medicine 2022. PMID: 35777842


  14. Mayfield JJ, McKee KY, Zier LS, Kohlwes RJ. Hearts and Minds: an Exercise in Clinical Reasoning. Journal of general internal medicine 2021. PMID: 33765236


  15. Yogeswaran V, Ramakrishna S, MacGregor JS, Zier L, Goldschlager N. Pregnancy-Associated Chest Pain: A Case of Spontaneous Coronary Artery Dissection. Case reports in cardiology 2021. PMID: 33510913


  16. Paul J Marano, Alexandra B Steverson, Caren Chen, Yifei Ma, Rachel J Stern, Jonathan Davis, Priscilla Hsue, Lucas S Zier. Abstract 13880: A Novel, Evidence-based, Standardized Discharge Checklist Reduces Thirty Day Heart Failure Readmissions in an Urban Safety Net Hospital. TO REMOVE 2020. PMID:


  17. Alexandra B Steverson, Paul Marano, Caren Chen, Yifei Ma, Rachel Stern, Jonathan D Davis, Priscilla Hsue, Lucas S Zier. Abstract 16520: Predictors of Thirty Day Readmission in a Vulnerable and Underserved Urban Heart Failure Population. TO REMOVE 2020. PMID:


  18. DesJardin JT, Manicardi M, Svetlichnaya Y, Kolaitis NA, Papolos AI, Selby VN, Zier LS, Klein L, Aras MA, Yao FY, Roberts JP, De Marco T. Non-Invasive Estimation of Pulmonary Vascular Resistance Improves Portopulmonary Hypertension Screening in Liver Transplant Candidates. Clinical transplantation 2019. PMID: 31074522


  20. Agarwal A, Cunnington C, Sabanayagam A, Zier L, McCulloch CE, Harris IS, Foster E, Atkinson D, Bryan A, Jenkins P, Dua J, Parker MJ, Karunaratne D, Moore JA, Meadows J, Clarke B, Hoschtitzky JA, Mahadevan VS. Cardiopulmonary exercise testing in the evaluation of liver disease in adults who have had the Fontan operation. Archives of cardiovascular diseases 2017. PMID: 29198937


  24. Zier LS, Sievert H, Mahadevan VS. To close or not to close: contemporary indications for patent foramen ovale closure. Expert review of cardiovascular therapy 2016. PMID: 27616622


  26. Zier LS, Sottile PD, Hong SY, Weissfield LA, White DB. Surrogate decision makers' interpretation of prognostic information: a mixed-methods study. Annals of internal medicine 2012. PMID: 22393131


  28. Zier LS, Burack JH, Micco G, Chipman AK, Frank JA, White DB. Surrogate decision makers' responses to physicians' predictions of medical futility. Volume 136 of Issue 1. Chest 2009. PMID: 19318665


  29. Zier LS, Burack JH, Micco G, Chipman AK, Frank JA, Luce JM, White DB. Doubt and belief in physicians' ability to prognosticate during critical illness: the perspective of surrogate decision makers. Volume 36 of Issue 8. Critical care medicine 2008. PMID: 18596630