Mary Gray, MD


Mary O. Gray, M.D. is Medical Director of Cardiology Clinical Services at Zuckerberg San Francisco General and Professor of Medicine at UC San Francisco. She serves as attending physician for the ZSFG inpatient service, consult service, echocardiography laboratory, cardiac device clinic, general cardiology clinic, and anticoagulation clinic.

Dr. Gray received her medical degree from UC San Diego School of Medicine, where she was also medicine resident and chief medicine resident. She completed a clinical pharmacology fellowship and general cardiology fellowship at UC San Francisco. She holds hospital leadership roles including Chair of ZSFG Medication Error Reduction Plan Committee and Associate Medical Director for ZSFG Risk Management.
B.A.S., - Biology and English, Stanford University
- Chief Medicine Resident, UC San Diego Dept of Medicine
- Medicine Resident, UC San Diego Dept of Medicine
M.D., - Medical Student, UC San Diego School of Medicine
- Clinical Cardiology Fellow, UC San Francisco
- Postdoctoral Research Fellow, UC San Francisco
  1. Alcohol in moderation, cardioprotection, and neuroprotection: epidemiological considerations and mechanistic studies.
  2. Signals from type 1 sphingosine 1-phosphate receptors enhance adult mouse cardiac myocyte survival during hypoxia.
  3. Transgenic MMP-2 expression induces latent cardiac mitochondrial dysfunction.
  4. Poly(ADP-ribose) polymerase-1 hyperactivation and impairment of mitochondrial respiratory chain complex I function in reperfused mouse hearts.
  5. MnSOD in mouse heart: acute responses to ischemic preconditioning and ischemia-reperfusion injury.
  6. Preservation of base-line hemodynamic function and loss of inducible cardioprotection in adult mice lacking protein kinase C epsilon.
  7. Effect of anoxia/reperfusion on the reversible active/de-active transition of NADH-ubiquinone oxidoreductase (complex I) in rat heart.
  8. Moderate alcohol consumption induces sustained cardiac protection by activating PKC-epsilon and Akt.
  9. Cardioprotection mediated by sphingosine-1-phosphate and ganglioside GM-1 in wild-type and PKC epsilon knockout mouse hearts.