Neal Benowitz, MD

Smith TT, Luo X, Benowitz NL, Colby SM, McClernon FJ, Strasser AA, Tidey JW, Donny EC, Hatsukami DK. The impact of nicotine reduction on cigarette reinforcement value within a marketplace containing alternative nicotine delivery products: A secondary analysis of a multi-site trial. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2025. PMID: 40613327

Wu AHB, Benowitz N. Theoretical and retrograde calculation of blood alcohol: wide estimates using the Academy Standards Board for calculations over an extended period of time. Laboratory medicine 2025. PMID: 40973110

Allen AM, Cao Q, Stayer LG, Luo X, Jensen J, Pang RD, Allen S, Donny EC, Benowitz N, Smith T, Hatsukami D. Differences in Combustible Cigarette Smoking-Related Biomarkers by Hormonal Contraceptive Use: An Exploratory Study. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2025. PMID: 39883066

Nichols AL, Marotta CB, Lukas HL, Friesenhahn NJ, Wagenaar D, Mayo SL, Dougherty DA, Benowitz N, Gao W, Muthusamy AK, Lester HA. Continuous Nicotine Monitors for Personal Nicotine Pharmacokinetics: A Receptor-Aware Research Agenda. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2025. PMID: 40079271

Brouwer AF, Shafie-Khorassani F, Benowitz N, Shi N, Baker TB, Hayes-Birchler T, Piper ME. Urinary tobacco and nicotine exposure biomarkers as predictors of transitions between cigarette and e-cigarette use in the Exhale longitudinal cohort study. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2025. PMID: 40832891

Christen SE, Bekka E, Schmid Y, Benowitz NL, Liakoni E. Caffeine, nicotine, cannabis, and psilocybin: Pharmacology, toxicology, and potential therapeutic uses of four naturally occurring psychoactive substances. Swiss medical weekly 2025. PMID: 40811135

Rigotti NA, Benowitz NL, Prochaska JJ, Rubinstein M, Clarke A, Blumenstein B, Cain DF, Jacobs C. Cytisinicline for Smoking Cessation: The ORCA Phase 3 Replication Randomized Clinical Trial. JAMA internal medicine 2025. PMID: 40257755

Mir H, Eisenberg MJ, Benowitz NL, Cowley E, Heshmati J, Jha P, Khara M, Mullen KA, Ofori SN, Rigotti NA, San Cartier R. Canadian Cardiovascular Society Clinical Practice Update on Contemporary Approaches to Smoking Cessation. The Canadian journal of cardiology 2025. PMID: 40340054

St Helen G, Havel C, Addo N, Criner N, Jacob P, Benowitz N. Using a loose-leaf vaporizer to study tobacco-cannabis co-administration: A proof-of-concept study. Drug and alcohol dependence 2025. PMID: 40328077

Benowitz NL. Predicting Cardiovascular Risk With Use of Various Tobacco Products. Circulation 2025. PMID: 40193542

Benowitz NL, Yang HY, Jacob P, St Helen G. Nicotine Dosimetry in Evaluating Electronic Cigarettes Compared to Cigarette Smoking: Implications for Tobacco Regulatory Science. Chemical research in toxicology 2025. PMID: 40094483

Rezk-Hanna M, Ben Taleb Z, Benowitz NL. Nicotine levels in flavoured hookah (waterpipe) tobacco products: discrepancies between labelled and measured levels. Tobacco control 2025. PMID: 39798996

Dennison Himmelfarb CR, Benowitz NL, Blank MD, Bhatnagar A, Chase PJ, Davis EM, Fetterman JL, Keller-Hamilton B, Ogungbe O, Page RL, Rezk-Hanna M, Robertson RM, Whitsel LP, American Heart Association Advocacy Coordinating Committee. Impact of Smokeless Oral Nicotine Products on Cardiovascular Disease: Implications for Policy, Prevention, and Treatment: A Policy Statement From the American Heart Association. Circulation 2024. PMID: 39624904

Duong C, Rodriquez EJ, Hinerman AS, Hooshmand S, Claudel SE, Benowitz NL, Perez-Stable EJ. Tobacco Biomarkers by Latino Heritage and Race, U.S., 2007-2014 National Health and Nutrition Examination Survey. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2024. PMID: 39348098

Liakoni E, Christen SE, Benowitz NL. E-cigarettes, synthetic nicotine, heated-tobacco and smokeless nicotine delivery products: the nicotine landscape beyond combustible cigarettes. Swiss medical weekly 2024. PMID: 39835719

Rigotti NA, Benowitz NL, Jacobs C. Cytisinicline For E-Cigarette Cessation-Reply. JAMA internal medicine 2024. PMID: 39250151

Matt GE, Greiner L, Record RA, Wipfli H, Long J, Dodder NG, Hoh E, Lopez Galvez N, Novotny TE, Quintana PJE, Destaillats H, Tang X, Snijders AM, Mao JH, Hang B, Schick S, Jacob P, Talbot P, Mahabee-Gittens EM, Merianos AL, Northrup TF, Gundel L, Benowitz NL. Policy-relevant differences between secondhand and thirdhand smoke: strengthening protections from involuntary exposure to tobacco smoke pollutants. Tobacco control 2023. PMID: 37263783

Prochaska JJ, Vogel EA, Oppezzo M, Skan J, Knox M, Chieng A, Crouch MC, Aikens RC, Schnellbaecher M, Benowitz NL. A randomized controlled trial evaluation of a smoking cessation and physical activity intervention delivered via telemedicine in the Norton Sound region of Alaska. Addictive behaviors 2024. PMID: 39348775

Christen SE, Hermann L, Bekka E, Vonwyl C, Hammann F, van der Velpen V, Eap CB, Benowitz NL, Haschke M, Liakoni E. Pharmacokinetics and pharmacodynamics of inhaled nicotine salt and free-base using an e-cigarette: A randomized crossover study. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2024. PMID: 38597729

Rigotti NA, Benowitz NL, Prochaska JJ, Cain DF, Ball J, Clarke A, Blumenstein BA, Jacobs C. Cytisinicline for Vaping Cessation in Adults Using Nicotine E-Cigarettes: The ORCA-V1 Randomized Clinical Trial. JAMA internal medicine 2024. PMID: 38709500

Hatsukami DK, Jensen JA, Carroll DM, Luo X, Strayer LG, Cao Q, Hecht SS, Murphy SE, Carmella SG, Denlinger-Apte RL, Colby S, Strasser AA, McClernon FJ, Tidey J, Benowitz NL, Donny EC. Reduced nicotine in cigarettes in a marketplace with alternative nicotine systems: randomized clinical trial. Lancet regional health. Americas 2024. PMID: 38911348

Leavens ELS, Lambart L, Diaz FJ, Wagener TL, Ahluwalia JS, Benowitz N, Nollen NL. Nicotine delivery and changes in withdrawal and craving during acute electronic cigarette, heated tobacco product, and cigarette use among a sample of Black and White people who smoke. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2023. PMID: 38097340

Leavens ELS, Lambart LM, St Helen G, Benowitz NL, Mayo MS, Farhad Mahmud KM, Arnold MJ, Nollen NL. Menthol versus tobacco e-liquid flavor: Impact on acute subjective effects, puff patterns, and intentions for use among Black and White menthol smokers. Addictive behaviors 2024. PMID: 38613857

Haynes A, Winnall WR, Brennan E, Dunstone K, Benowitz NL, Ashley DL, Samet JM, Hatsukami DK, Wakefield MA. Tobacco constituents, flavorants, and paper permeability of factory-made and roll-your-own cigarettes on the Australian market. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2023. PMID: 37462724

Pomerleau OF, Benowitz NL, Stitzer ML, Henningfield JE, Hatsukami DK, Corrigall WA, Perkins KA, Lando HA. Srnt As An Outgrowth Of The 1988 Surgeon General's Report On Nicotine Addiction: Reflections Of The Early Presidents. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2023. PMID: 37584666

Rezk-Hanna M, Rossman MJ, Ludwig K, Sakti P, Cheng CW, Brecht ML, Benowitz NL, Seals DR. Electronic Hookah (Waterpipe) Vaping Reduces Vascular Endothelial Function: The Role of Nicotine. American journal of physiology. Heart and circulatory physiology 2023. PMID: 38133618

Gravely S, Driezen P, Shahab L, McClure EA, Hyland A, Cummings KM, East KA, Chan GCK, Walsh H, Benowitz NL, Gartner CE, Fong GT, Quah ACK, Smith DM. Associations of Cannabis Use, High-Risk Alcohol Use, and Depressive Symptomology with Motivation and Attempts to Quit Cigarette Smoking Among Adults: Findings from the 2020 ITC Four Country Smoking and Vaping Survey. International journal of mental health and addiction 2023. PMID: 40703248

Rezk-Hanna M, Adolfo A, Warda US, Brecht ML, Benowitz NL. Association of non-daily hookah tobacco smoking and cardiovascular disease-related exposure biomarkers among U.S. users: The Population Assessment of Tobacco and Health Study. Preventive medicine reports 2023. PMID: 37753385

Dai HD, Benowitz NL, Rogan E, Degarege A, Buckley J, Khan AS. Biomarkers of Toxic Exposure and Oxidative Stress Among U.S. Adult Users of Premium Cigar Versus Other Cigar Subtypes: 2013-2019. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2023. PMID: 37506235

Giberson J, Nardone N, Addo N, Khan S, Jacob P, Benowitz N, St Helen G. Nicotine Intake in Adult Pod E-Cigarette Users: Impact of User and Device Characteristics. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2023. PMID: 37061820

Rigotti NA, Benowitz NL, Prochaska J, Leischow S, Nides M, Blumenstein B, Clarke A, Cain D, Jacobs C. Cytisinicline for Smoking Cessation: A Randomized Clinical Trial. JAMA 2023. PMID: 37432430

Islam T, Eckel S, Liu F, Barrington-Trimis J, Harlow AF, Benowitz N, Leventhal A, McConnell R, Cho J. Effects of dual use of e-cigarette and cannabis during adolescence on cigarette use in young adulthood. Tobacco control 2023. PMID: 37147126

Benowitz NL, Warner KE, Myers ML, Hatsukami D, Berman ML, Vallone D, Cohen JE. How the FDA Can Improve Public Health - Helping People Stop Smoking. The New England journal of medicine 2023. PMID: 37092791

Bierut LJ, Hendershot TP, Benowitz NL, Cummings KM, Mermelstein RJ, Piper ME, Vrieze SI, Wagener TL, Nelms MD, Ives C, Maiese D, Hamilton CM, Swan GE. Smoking cessation, harm reduction, and biomarkers protocols in the PhenX Toolkit: Tools for standardized data collection. Addiction neuroscience 2023. PMID: 38645895

Jacobs C, Fonseca M, Rigotti NA, Benowitz N, Clarke A, Cain D. A Phase I, Double-blind, Randomized, Placebo-controlled, Single Dose-escalation Study to Evaluate the Tolerability and Safety of Cytisinicline in Adult Smokers. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2022. PMID: 36198104

Yang H, Wang X, Wang P, He L, Schick SF, Jacob P, Benowitz N, Gundel LA, Zhu C, Xia Y, Inman JL, Chang H, Snijders AM, Mao JH, Hang B. Thirdhand tobacco smoke exposure increases the genetic background-dependent risk of pan-tumor development in Collaborative Cross mice. Environment international 2023. PMID: 36940581

Warner KE, Benowitz NL, McNeill A, Rigotti NA. Nicotine e-cigarettes as a tool for smoking cessation. Nature medicine 2023. PMID: 36788367

Mendelsohn CP, Hall W, Borland R, Wodak A, Beaglehole R, Benowitz NL, Britton J, Bullen C, Etter JF, McNeill A, Rigotti NA. A critique of the Australian National Health and Medical Research Council CEO statement on electronic cigarettes. Addiction (Abingdon, England) 2023. PMID: 36808672

Shafie-Khorassani F, Piper ME, Jorenby DE, Baker TB, Benowitz NL, Hayes-Birchler T, Meza R, Brouwer AF. Associations of demographics, dependence, and biomarkers with transitions in tobacco product use in a cohort of cigarette users and dual users of cigarettes and e-cigarettes. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2022. PMID: 36037523

Rebuli ME, Rose JJ, No?l A, Croft DP, Benowitz NL, Cohen AH, Goniewicz ML, Larsen BT, Leigh N, McGraw MD, Melzer AC, Penn AL, Rahman I, Upson D, Crotty Alexander LE, Ewart G, Jaspers I, Jordt SE, Kligerman S, Loughlin CE, McConnell R, Neptune ER, Nguyen TB, Pinkerton KE, Witek TJ. The E-cigarette or Vaping Product Use-Associated Lung Injury Epidemic: Pathogenesis, Management, and Future Directions: An Official American Thoracic Society Workshop Report. Annals of the American Thoracic Society 2023. PMID: 36584985

Benowitz NL, Havel C, Jacob P, O'Shea DF, Wu D, Fowles J. Vaping THC-O Acetate: Potential for Another EVALI Epidemic. Journal of medical toxicology : official journal of the American College of Medical Toxicology 2022. PMID: 36508081

Rosen RL, Ramasubramani RS, Benowitz NL, Gandhi KK, Williams JM. Caffeine levels and dietary intake in smokers with schizophrenia and bipolar disorder. Psychiatry research 2022. PMID: 36470161

White CM, Watson C, Bravo Cardenas R, Ngac P, Valentin-Blasini L, Blount BC, Koopmeiners JS, Denlinger-Apte RL, Pacek LR, Benowitz NL, Hatsukami DK, Donny EC, Carpenter MJ, Smith TT. Early Changes in Puffing Intensity When Exclusively Using Open-Label Very Low Nicotine Content Cigarettes. TO REMOVE 2022. PMID: 35524988

Masson CL, Gubner NR, Benowitz N, Hosakote S, Le T, Guydish JR. Lifetime use of non-nicotine drugs in electronic cigarette devices among a sample of individuals in substance use disorder treatment. Addictive behaviors reports 2022. PMID: 36341309

Young-Wolff KC, Ray GT, Alexeeff SE, Benowitz N, Adams SR, Does MB, Goler N, Ansley D, Conway A, Avalos LA. Association of cannabis use during pregnancy with severe acute respiratory syndrome coronavirus 2 infection: a retrospective cohort study. Addiction (Abingdon, England) 2022. PMID: 36189777

Sanders MA, Oppezzo M, Skan J, Benowitz NL, Schnellbaecher M, Prochaska JJ. Demographic and cultural correlates of traditional eating among Alaska Native adults at risk for cardiovascular disease. PloS one 2022. PMID: 36178914

McColl ER, Kwok J, Benowitz NL, Patten CA, Hughes CA, Koller KR, Flanagan CA, Thomas TK, Hiratsuka VY, Tyndale RF, Piquette-Miller M. The Effect of Tobacco Use on the Expression of Placental Transporters in Alaska Native Women. Clinical pharmacology and therapeutics 2022. PMID: 36053152

Benowitz NL, Goniewicz ML, Halpern-Felsher B, Krishnan-Sarin S, Ling PM, O'Connor RJ, Pentz MA, Robertson RM, Bhatnagar A. Tobacco product use and the risks of SARS-CoV-2 infection and COVID-19: current understanding and recommendations for future research. The Lancet. Respiratory medicine 2022. PMID: 35985357

Oppezzo M, Knox M, Skan J, Chieng A, Crouch M, Aikens RC, Benowitz NL, Schnellbaecher M, Prochaska JJ. Traditional Heart-Healthy Diet and Medication Adherence in the Norton Sound Region: An 18-Month Telehealth Intervention. International journal of environmental research and public health 2022. PMID: 36011519

Tang X, Benowitz N, Gundel L, Hang B, Havel CM, Hoh E, Jacob Iii P, Mao JH, Martins-Green M, Matt GE, Quintana PJE, Russell ML, Sarker A, Schick SF, Snijders AM, Destaillats H. Thirdhand Exposures to Tobacco-Specific Nitrosamines through Inhalation, Dust Ingestion, Dermal Uptake, and Epidermal Chemistry. Environmental science & technology 2022. PMID: 35900278

Klemperer EM, Luo X, Jensen J, al'Absi M, Cinciripini PM, Robinson JD, Drobes DJ, McClernon J, Strasser AA, Strayer LG, Vandrey R, Benowitz NL, Donny EC, Hatsukami DK. Smoking abstinence and cessation-related outcomes one month after an immediate versus gradual reduction in nicotine content of cigarettes. Preventive medicine 2022. PMID: 35870575

Rezk-Hanna M, Warda US, Stokes AC, Fetterman J, Li J, Macey PM, Darawad M, Song Y, Ben Taleb Z, Brecht ML, Benowitz NL. Associations of Smokeless Tobacco Use With Cardiovascular Disease Risk: Insights From the Population Assessment of Tobacco and Health Study. TO REMOVE 2022. PMID: 34999825

Rice M, Nollen NL, Ahluwalia JS, Benowitz N, Woodcock A, Pulvers K. Effects of Marijuana Use on Smokers Switching to E-cigarettes in a Randomized Clinical Trial. TO REMOVE 2022. PMID: 35022796

Cox LS, Nollen NL, Mayo MS, Faseru B, Greiner A, Ellerbeck EF, Krebill R, Tyndale RF, Benowitz NL, Ahluwalia JS. Effect of Varenicline Added to Counseling on Smoking Cessation Among African American Daily Smokers: The Kick It at Swope IV Randomized Clinical Trial. JAMA 2022. PMID: 35699705

Jacob P, Chan L, Cheung P, Bello K, Yu L, StHelen G, Benowitz NL. Minor Tobacco Alkaloids as Biomarkers to Distinguish Combusted Tobacco Use From Electronic Nicotine Delivery Systems Use. Two New Analytical Methods. Frontiers in chemistry 2022. PMID: 35720984

Moazed F, Hendrickson C, Jauregui A, Gotts J, Conroy A, Delucchi K, Zhuo H, Arambulo M, Vessel K, Ke S, Deiss T, Ni A, Leligdowicz A, Abbott J, Cohen MJ, Sinha P, Gomez A, Kangelaris K, Kornblith L, Matthay M, Benowitz N, Liu K, Calfee CS. Cigarette Smoke Exposure and ARDS in Sepsis: Epidemiology, Clinical Features, and Biologic Markers. TO REMOVE 2022. PMID: 35050845

Benowitz NL. The Central Role of pH in the Clinical Pharmacology of Nicotine: Implications for Abuse Liability, Cigarette Harm Reduction and FDA Regulation. TO REMOVE 2022. PMID: 35220591

Stroud LR, Papandonatos GD, Jao NC, Niaura R, Buka S, Benowitz NL. Maternal nicotine metabolism moderates the impact of maternal cigarette smoking on infant birth weight: A Collaborative Perinatal Project investigation. TO REMOVE 2022. PMID: 35247723

Aquilina NJ, Havel CM, Benowitz NL, Jacob P. Tobacco-specific and combustion pollutants in settled house dust in Malta. TO REMOVE 2022. PMID: 35497707

Dai H, Benowitz NL, Achutan C, Farazi PA, Degarege A, Khan AS. Exposure to Toxicants Associated With Use and Transitions Between Cigarettes, e-Cigarettes, and No Tobacco. TO REMOVE 2022. PMID: 35142830

Balfour DJK, Benowitz NL, Colby SM, Hatsukami DK, Lando HA, Leischow SJ, Lerman C, Mermelstein RJ, Niaura R, Perkins KA, Pomerleau OF, Rigotti NA, Swan GE, Warner KE, West R. Balfour et al. Respond. TO REMOVE 2022. PMID: 34936419

Balfour DJK, Benowitz NL, Colby SM, Hatsukami DK, Lando HA, Leischow SJ, Lerman C, Mermelstein RJ, Niaura R, Perkins KA, Pomerleau OF, Rigotti NA, Swan GE, Warner KE, West R. Balfour et al. Respond. TO REMOVE 2022. PMID: 34936414

Palmer AM, Toll BA, Carpenter MJ, Donny EC, Hatsukami DK, Rojewski AM, Smith TT, Sofuoglu M, Thrul J, Benowitz NL. Reappraising Choice in Addiction: Novel Conceptualizations and Treatments for Tobacco Use Disorder. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2021. PMID: 34270729

Cwalina SN, McConnell R, Benowitz NL, Barrington-Trimis JL. Tobacco-free Nicotine - New Name, Same Scheme? TO REMOVE 2021. PMID: 34919358

Chenoweth MJ, Peng AR, Zhu AZX, Cox LS, Nollen NL, Ahluwalia JS, Benowitz NL, Knight J, Swardfager W, Tyndale RF. Does sex alter the relationship between CYP2B6 variation, hydroxybupropion concentration, and bupropion-aided smoking cessation in African Americans? A moderated mediation analysis. TO REMOVE 2021. PMID: 34791718

Aquilina NJ, Jacob P, Benowitz NL, Fsadni P, Montefort S. Secondhand smoke exposure in school children in Malta assessed through urinary biomarkers. TO REMOVE 2021. PMID: 34822856

Aquilina NJ, Havel CM, Harrison RM, Ho KF, Benowitz NL, Jacob Iii P. Determination of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone (NNK) arising from tobacco smoke in airborne particulate matter. TO REMOVE 2021. PMID: 34991253

Benowitz NL, Liakoni E. Tobacco use disorder and cardiovascular health. TO REMOVE 2021. PMID: 34590373

Chenoweth MJ, Cox LS, Nollen NL, Ahluwalia JS, Benowitz NL, Lerman C, Knight J, Tyndale RF. Analyses of nicotine metabolism biomarker genetics stratified by sex in African and European Americans. TO REMOVE 2021. PMID: 34599228

El-Boraie A, Tanner JA, Zhu AZX, Claw KG, Prasad B, Schuetz EG, Thummel KE, Fukunaga K, Mushiroda T, Kubo M, Benowitz NL, Lerman C, Tyndale RF. Functional Characterization Of Novel Rare CYP2A6 Variants And Potential Implications For Clinical Outcomes. Clinical and translational science 2021. PMID: 34476898

Nides M, Rigotti NA, Benowitz N, Clarke A, Jacobs C. A Multicenter, Double-Blind, Randomized, Placebo-Controlled Phase 2b Trial of Cytisinicline in Adult Smokers (The ORCA-1 Trial). Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2021. PMID: 33847362

Balfour DJK, Benowitz NL, Colby SM, Hatsukami DK, Lando HA, Leischow SJ, Lerman C, Mermelstein RJ, Niaura R, Perkins KA, Pomerleau OF, Rigotti NA, Swan GE, Warner KE, West R. Balancing Consideration of the Risks and Benefits of E-Cigarettes. American journal of public health 2021. PMID: 34410826

Benowitz NL, St Helen G, Liakoni E. Clinical Pharmacology of Electronic Nicotine Delivery Systems (ENDS): Implications for Benefits and Risks in the Promotion of the Combusted Tobacco Endgame. Journal of clinical pharmacology 2021. PMID: 34396553

Liakoni E, Tyndale RF, Jacob P, Dempsey DA, Addo N, Benowitz NL. Effect of race and glucuronidation rates on the relationship between nicotine metabolite ratio and nicotine clearance. Pharmacogenetics and genomics 2021. PMID: 33675323

Shi L, Hatsukami DK, Koopmeiners JS, Le CT, Benowitz NL, Donny EC, Luo X. A mixed effects model for analyzing area under the curve of longitudinally measured biomarkers with missing data. Pharmaceutical statistics 2021. PMID: 34151513

Liu J, Benowitz NL, Hatsukami DK, Havel CM, Lazcano-Ponce E, Strasser AA, Jacob P. 3-Ethenylpyridine Measured in Urine of Active and Passive Smokers: A Promising Biomarker and Toxicological Implications. Chemical research in toxicology 2021. PMID: 33998799

Beard E, Jackson SE, Anthenelli RM, Benowitz NL, Aubin LS, McRae T, Lawrence D, Russ C, Krishen A, Evins AE, West R. Estimation of risk of neuropsychiatric adverse events from varenicline, bupropion and nicotine patch versus placebo: secondary analysis of results from the EAGLES trial using Bayes factors. Addiction (Abingdon, England) 2021. PMID: 33885203

Giratallah HK, Chenoweth MJ, Addo N, Ahluwalia JS, Cox LS, Lerman C, George TP, Benowitz NL, Tyndale RF. Nicotine metabolite ratio: Comparison of the three urinary versions to the plasma version and nicotine clearance in three clinical studies. Drug and alcohol dependence 2021. PMID: 33873029

Northrup TF, Stotts AL, Suchting R, Matt GE, Quintana PJE, Khan AM, Green C, Klawans MR, Johnson M, Benowitz N, Jacob P, Hoh E, Hovell MF, Stewart CJ. Thirdhand smoke associations with the gut microbiomes of infants admitted to a neonatal intensive care unit: An observational study. Environmental research 2021. PMID: 33865820

Vogel EA, Benowitz NL, Skan J, Schnellbaecher M, Prochaska JJ. Correlates of the nicotine metabolite ratio in Alaska Native people who smoke cigarettes. Experimental and clinical psychopharmacology 2021. PMID: 33856821

Prochaska JJ, Vogel EA, Benowitz N. Nicotine delivery and cigarette equivalents from vaping a JUULpod. Tobacco control 2021. PMID: 33762429

Rezk-Hanna M, Seals DR, Rossman MJ, Gupta R, Nettle CO, Means A, Dobrin D, Cheng CW, Brecht ML, Mosenifar Z, Araujo JA, Benowitz NL. Ascorbic Acid Prevents Vascular Endothelial Dysfunction Induced by Electronic Hookah (Waterpipe) Vaping. Journal of the American Heart Association 2021. PMID: 33615833

Tarran R, Barr RG, Benowitz NL, Bhatnagar A, Chu HW, Dalton P, Doerschuk CM, Drummond MB, Gold DR, Goniewicz ML, Gross ER, Hansel NN, Hopke PK, Kloner RA, Mikheev VB, Neczypor EW, Pinkerton KE, Postow L, Rahman I, Samet JM, Salathe M, Stoney CM, Tsao PS, Widome R, Xia T, Xiao D, Wold LE. E-Cigarettes and Cardiopulmonary Health. Function (Oxford, England) 2021. PMID: 33748758

Aquilina NJ, Havel CM, Cheung P, Harrison RM, Ho KF, Benowitz NL, Jacob Iii P. Ubiquitous atmospheric contamination by tobacco smoke: Nicotine and a new marker for tobacco smoke-derived particulate matter, nicotelline. Environment international 2021. PMID: 33561671

Nollen NL, Ahluwalia JS, Sanderson Cox L, Okuyemi K, Lawrence D, Samuels L, Benowitz NL. Assessment of Racial Differences in Pharmacotherapy Efficacy for Smoking Cessation: Secondary Analysis of the EAGLES Randomized Clinical Trial. JAMA network open 2021. PMID: 33464316

El-Boraie A, Chenoweth MJ, Pouget JG, Benowitz NL, Fukunaga K, Mushiroda T, Kubo M, Nollen NL, Sanderson Cox L, Lerman C, Knight J, Tyndale RF. Transferability of Ancestry-Specific and Cross-Ancestry CYP2A6 Activity Genetic Risk Scores in African and European Populations. Clinical pharmacology and therapeutics 2021. PMID: 33300144

Denlinger-Apte RL, White CM, Donny EC, Hatsukami DK, Benowitz NL, Carpenter MJ, Smith TT. "I actually finally feel like the cigarettes aren't controlling me." - Interviews with participants smoking very low nicotine content cigarettes during a residential study. Drug and alcohol dependence 2020. PMID: 33383351

Knox M, Skan J, Benowitz NL, Schnellbaecher M, Prochaska JJ. Recruitment best practices of a cardiovascular risk reduction randomised control trial in rural Alaska Native communities. International journal of circumpolar health 2020. PMID: 32787541

Benowitz NL, St Helen G, Nardone N, Addo N, Zhang JJ, Harvanko AM, Calfee CS, Jacob P. Twenty-Four-Hour Cardiovascular Effects of Electronic Cigarettes Compared With Cigarette Smoking in Dual Users. Journal of the American Heart Association 2020. PMID: 33208019

Evins AE, West R, Benowitz NL, Russ C, Lawrence D, McRae T, Maravic MC, Heffner JL, Anthenelli RM. Efficacy and Safety of Pharmacotherapeutic Smoking Cessation Aids in Schizophrenia Spectrum Disorders: Subgroup Analysis of EAGLES. Psychiatric services (Washington, D.C.) 2020. PMID: 33138708

Pulvers K, Nollen NL, Rice M, Schmid CH, Qu K, Benowitz NL, Ahluwalia JS. Effect of Pod e-Cigarettes vs Cigarettes on Carcinogen Exposure Among African American and Latinx Smokers: A Randomized Clinical Trial. JAMA network open 2020. PMID: 33206193

Carroll DM, Cigan S, Ikuemonisan J, Hammonds T, Stepanov I, St Helen G, Benowitz N, Hatsukami DK. Relationships between race, gender, and spot urine levels of biomarkers of tobacco exposure vary based on how creatinine is handled in analyses. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2020. PMID: 32598452

Wakefield MA, Dunstone K, Brennan E, Vittiglia A, Scollo M, Durkin SJ, Hoek J, Thrasher J, Hatsukami D, Benowitz N, Samet JM. Australian smokers' experiences and perceptions of recessed and firm filter cigarettes. Tobacco control 2020. PMID: 33115960

Piper ME, Baker TB, Benowitz NL, Jorenby DE. Corrigendum to: Changes in Use Patterns Over 1 Year Among Smokers and Dual Users of Combustible and Electronic Cigarettes. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2019. PMID: 31609417

Chaffee BW, Jacob P, Couch ET, Benowitz NL. Exposure to a Tobacco-Specific Carcinogen Among Adolescent Smokeless Tobacco Users in Rural California, United States. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2019. PMID: 31504879

Piper ME, Baker TB, Mermelstein R, Benowitz N, Jorenby DE. Relations among cigarette dependence, e-cigarette dependence, and key dependence criteria among dual users of combustible and e-cigarettes. Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors 2020. PMID: 32955271

Kovar L, Selzer D, Britz H, Benowitz N, St Helen G, Kohl Y, Bals R, Lehr T. Comprehensive Parent-Metabolite PBPK/PD Modeling Insights into Nicotine Replacement Therapy Strategies. Clinical pharmacokinetics 2020. PMID: 32166575

Nardone N, Giberson J, Prochaska JJ, Jain S, Benowitz NL. A Mobile Health Intervention for Adolescents Exposed to Secondhand Smoke: Pilot Feasibility and Efficacy Study. JMIR formative research 2020. PMID: 32812888

Nardone N, Jain S, Benowitz NL. Biomarkers of Exposure to Nicotine and Tobacco-specific Nitrosamines in Adolescent Blunt Users. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2019. PMID: 31433049

Liakoni E, Nardone N, St Helen G, Dempsey DA, Tyndale RF, Benowitz NL. Effects of Nicotine Metabolic Rate on Cigarette Reinforcement. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2019. PMID: 31725872

Cao W, Hecht SS, Murphy SE, Chu H, Benowitz NL, Donny EC, Hatsukami DK, Luo X. Analysis of Multiple Biomarkers Using Structural Equation Modeling. TO REMOVE 2020. PMID: 35530662

Moazed F, Hendrickson C, Conroy A, Kornblith LZ, Benowitz NL, Delucchi K, Cohen MJ, Calfee CS. Cigarette Smoking and ARDS After Blunt Trauma: The Influence of Changing Smoking Patterns and Resuscitation Practices. Chest 2020. PMID: 32574574

Epperson AE, Crouch M, Skan J, Benowitz NL, Schnellbaecher M, Prochaska JJ. Cultural and demographic correlates of dual tobacco use in a sample of Alaska Native adults who smoke cigarettes. Tobacco induced diseases 2020. PMID: 32587486

Benowitz NL, Bernert JT, Foulds J, Hecht SS, Jacob P, Jarvis MJ, Joseph A, Oncken C, Piper ME. Biochemical Verification of Tobacco Use and Abstinence: 2019 Update. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2019. PMID: 31570931

Jacob P, St Helen G, Yu L, Nardone N, Havel C, Cheung P, Benowitz NL. Biomarkers of Exposure for Dual Use of Electronic Cigarettes and Combustible Cigarettes: Nicotelline, NNAL, and Total Nicotine Equivalents. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2019. PMID: 31833541

Harvanko AM, Havel CM, Jacob P, Benowitz NL. Characterization of Nicotine Salts in 23 Electronic Cigarette Refill Liquids. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2019. PMID: 31821492

Carroll DM, Strayer L, Nardone N, Pacek LR, Kozink RV, Tessier K, McClernon J, Benowitz N, Bickel WK, Hatsukami D. Development and Piloting Testing of An Experimental Tobacco and Nicotine Product Marketplace. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2019. PMID: 31603515

Piper ME, Baker TB, Benowitz NL, Jorenby DE. Changes in Use Patterns OVER ONE YEAR Among Smokers and Dual Users of Combustible and electronic cigarettes. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2019. PMID: 31058284

Piper ME, Baker TB, Benowitz NL, Smith SS, Jorenby DE. E-cigarette Dependence Measures in Dual Users: Reliability and Relations with Dependence Criteria and E-Cigarette Cessation. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2019. PMID: 30874804

Schnoll R, Paul Wileyto E, Gross R, Hitsman B, Hawk LW, Cinciripini P, George TP, Benowitz NL, Fen Lubitz S, Ashare R, Tyndale RF, Lerman C. Evaluation of nicotine patch adherence measurement using self-report and saliva cotinine among abstainers in a smoking cessation trial. Drug and alcohol dependence 2020. PMID: 32224420

Rezk-Hanna M, Nelson MD, Rader F, Benowitz NL, Rosenberry R, Chang LC, Li N, Tashkin DP, Elashoff RM, Victor RG. Peripheral Blood Flow Changes to Cutaneous and Muscular Beds in Response to Acute Hookah Smoking. The American journal of cardiology 2020. PMID: 32278465

Park EY, Park E, Jeong BY, Park J, Lee DH, Benowitz NL, Lim MK. Comparison of smoking cessation rates of Quitline users in Korea between smokers of ultra-low nicotine yield cigarettes and other types of cigarette: a prospective study. Addiction (Abingdon, England) 2020. PMID: 32083364

Smith TT, Koopmeiners JS, Hatsukami DK, Tessier KM, Benowitz NL, Murphy SE, Strasser AA, Tidey JW, Blount BC, Valentin L, Bravo Cardenas R, Watson C, Pirkle JL, Donny EC. Mouth-Level Nicotine Intake Estimates from Discarded Filter Butts to Examine Compensatory Smoking in Low Nicotine Cigarettes. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2020. PMID: 32102909

Smith TT, Koopmeiners JS, White CM, Denlinger-Apte RL, Pacek LR, De Jesús VR, Wang L, Watson C, Blount BC, Hatsukami DK, Benowitz NL, Donny EC, Carpenter MJ. The Impact of Exclusive Use of Very Low Nicotine Cigarettes on Compensatory Smoking: An Inpatient Crossover Clinical Trial. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2020. PMID: 32102910

Carroll DM, Murphy SE, Benowitz NL, Strasser AA, Kotlyar M, Carmella SG, McClernon FJ, Pacek LR, Dermody SS, Vandrey RG, Donny EC, Hatsukami DK. Relationships between the nicotine metabolite ratio and a panel of exposure and effect biomarkers: findings from two studies of U.S. commercial cigarette smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2020. PMID: 32051195

Harvanko AM, St Helen G, Nardone N, Addo N, Benowitz NL. Twenty-four Hour Subjective and Pharmacological Effects of Ad Libitum Electronic and Combustible Cigarette Use among Dual Users. Addiction (Abingdon, England) 2019. PMID: 31837232

Benowitz NL, Helen GS, Nardone N, Cox LS, Jacob P. Urine Metabolites for Estimating Daily Intake of Nicotine from Cigarette Smoking. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2019. PMID: 30852610

St Helen G, Nardone N, Addo N, Dempsey D, Havel C, Jacob P, Benowitz N. Differences in nicotine intake and effects from electronic and combustible cigarettes among dual users. Addiction (Abingdon, England) 2019. PMID: 31691397

Benowitz NL. Seizures After Vaping Nicotine in Youth: A Canary or a Red Herring? The Journal of adolescent health : official publication of the Society for Adolescent Medicine 2020. PMID: 31866053

Denlinger-Apte RL, Kotlyar M, Koopmeiners JS, Tidey JW, Luo X, Benowitz NL, Jensen JA, Ikuemonisan JO, Pacek LR, Smith TT, Vandrey R, Donny EC, Hatsukami DK. Effects of Very Low Nicotine Content Cigarettes on Smoking Behavior and Biomarkers of Exposure in Menthol and Non-menthol Smokers. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2019. PMID: 31867637

Benowitz NL, Donny EC, Edwards KC, Hatsukami D, Smith TT. The Role of Compensation in Nicotine Reduction. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2019. PMID: 31867654

Nardone N, Jain S, Addo N, St Helen G, Jacob P, Benowitz NL. Sources and Biomarkers of Secondhand Tobacco Smoke Exposure in Urban Adolescents. Academic pediatrics 2019. PMID: 31866460

Nardone N, Shahid M, Strasser AA, Dempsey DA, Benowitz NL. The influence of nicotine metabolic rate on working memory over 6 hours of abstinence from nicotine. Pharmacology, biochemistry, and behavior 2019. PMID: 31812759

Voos N, Smith D, Kaiser L, Mahoney MC, Bradizza CM, Kozlowski LT, Benowitz NL, O'Connor RJ, Goniewicz ML. Effect of e-cigarette flavors on nicotine delivery and puffing topography: results from a randomized clinical trial of daily smokers. Psychopharmacology 2019. PMID: 31773209

Peng AR, Swardfager W, Benowitz NL, Ahluwalia JS, Lerman C, Nollen NL, Tyndale RF. Impact of Early Nausea on Varenicline Adherence and Smoking Cessation. Addiction (Abingdon, England) 2019. PMID: 31502736

Prochaska JJ, Benowitz NL. Current advances in research in treatment and recovery: Nicotine addiction. Science advances 2019. PMID: 31663029

Nollen NL, Mayo MS, Cox LS, Benowitz NL, Tyndale RF, Ellerbeck EF, Scheuermann TS, Ahluwalia JS. Factors that Explain Differences in Abstinence between Black and White Smokers: A Prospective Intervention Study. Journal of the National Cancer Institute 2019. PMID: 30657926

Rezk-Hanna M, Toyama J, Ikharo E, Brecht ML, Benowitz NL. E-Hookah Versus E-Cigarettes: Findings From Wave 2 of the PATH Study (2014-2015). American journal of preventive medicine 2019. PMID: 31564602

St Helen G, Liakoni E, Nardone N, Addo N, Jacob P, Benowitz NL. Comparison of systemic exposure to toxic and/or carcinogenic volatile organic compounds (VOCs) during vaping, smoking, and abstention. Cancer prevention research (Philadelphia, Pa.) 2019. PMID: 31554628

Benowitz N, Nardone N, St Helen G, Addo N, Jacob P, Liakoni E, Jain S, Hooshfar S, Lynch K. Quantitative biochemical screening for marijuana use and concordance with tobacco use in urban adolescents. Drug and alcohol dependence 2019. PMID: 31600618

Benowitz NL. E-cigarettes and dual nicotine replacement therapy for smoking cessation. The Lancet. Respiratory medicine 2019. PMID: 31515174

Weinstein JR, Diaz-Artiga A, Benowitz N, Thompson LM. Reductions in urinary metabolites of exposure to household air pollution in pregnant, rural Guatemalan women provided liquefied petroleum gas stoves. Journal of exposure science & environmental epidemiology 2019. PMID: 31477781

Liakoni E, St Helen G, Dempsey DA, Jacob P, Tyndale RF, Benowitz NL. Relationship between skin melanin index and nicotine pharmacokinetics in African American smokers. Drug and alcohol dependence 2019. PMID: 31521954

Rezk-Hanna M, Benowitz NL. Cardiovascular Effects of Hookah Smoking: Potential Implications for Cardiovascular Risk. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2018. PMID: 29660041

Piper ME, Baker TB, Benowitz NL, Kobinsky K, Jorenby DE. Dual Users Compared to Smokers: Demographics, Dependence, and Biomarkers. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2018. PMID: 30365010

St Helen G, Benowitz NL, Ko J, Jacob P, Gregorich SE, Pérez-Stable EJ, Murphy SE, Hecht SS, Hatsukami DK, Donny EC. Differences in exposure to toxic and/or carcinogenic volatile organic compounds between Black and White cigarette smokers. Journal of exposure science & environmental epidemiology 2019. PMID: 31406274

Nardone N, Helen GS, Addo N, Meighan S, Benowitz NL. JUUL electronic cigarettes: Nicotine exposure and the user experience. Drug and alcohol dependence 2019. PMID: 31408770

Tutka P, Vinnikov D, Courtney RJ, Benowitz NL. Cytisine for nicotine addiction treatment: A review of pharmacology, therapeutics and an update of clinical trial evidence for smoking cessation. Addiction (Abingdon, England) 2019. PMID: 31240783

Hatsukami DK, Luo X, Heskin AK, Tang MK, Carmella SG, Jensen J, Robinson JD, Vandrey R, Drobes DJ, Strasser AA, al'Absi M, Leischow S, Cinciripini PM, Koopmeiners J, Ikuemonisan J, Benowitz NL, Donny EC, Hecht SS. Effects of immediate versus gradual nicotine reduction in cigarettes on biomarkers of biological effects. Addiction (Abingdon, England) 2019. PMID: 31140663

St Helen G, Benowitz NL, Ahluwalia JS, Tyndale RF, Addo N, Gregorich SE, Pérez-Stable EJ, Cox LS. Black Light Smokers: How Nicotine Intake and Carcinogen Exposure Differ Across Various Biobehavioral Factors. Journal of the National Medical Association 2019. PMID: 31084916

Rezk-Hanna M, Mosenifar Z, Benowitz NL, Rader F, Rashid M, Davoren K, Moy NB, Doering L, Robbins W, Sarna L, Li N, Chang LC, Elashoff RM, Victor RG. High Carbon Monoxide Levels from Charcoal Combustion Mask Acute Endothelial Dysfunction Induced by Hookah (Waterpipe) Smoking in Young Adults. Circulation 2019. PMID: 30764644

Carmella SG, Heskin AK, Tang MK, Jensen J, Luo X, Le CT, Murphy SE, Benowitz NL, McClernon FJ, Vandrey R, Allen SS, Denlinger-Apte R, Cinciripini PM, Strasser AA, al'Absi M, Robinson JD, Donny EC, Hatsukami DK, Hecht SS. Longitudinal stability in cigarette smokers of urinary eicosanoid biomarkers of oxidative damage and inflammation. PloS one 2019. PMID: 31022220

Voos N, Kaiser L, Mahoney MC, Bradizza CM, Kozlowski LT, Benowitz NL, O'Connor RJ, Goniewicz ML. Randomized within-subject trial to evaluate smokers' initial perceptions, subjective effects and nicotine delivery across six vaporized nicotine products. Addiction (Abingdon, England) 2019. PMID: 30851137

Anthenelli RM, Gaffney M, Benowitz NL, West R, McRae T, Russ C, Lawrence D, St Aubin L, Krishen A, Evins AE. Predictors of Neuropsychiatric Adverse Events with Smoking Cessation Medications in the Randomized Controlled EAGLES Trial. Journal of general internal medicine 2019. PMID: 30847828

Evins AE, Benowitz NL, West R, Russ C, McRae T, Lawrence D, Krishen A, St Aubin L, Maravic MC, Anthenelli RM. Neuropsychiatric Safety and Efficacy of Varenicline, Bupropion, and Nicotine Patch in Smokers With Psychotic, Anxiety, and Mood Disorders in the EAGLES Trial. Journal of clinical psychopharmacology 2019. PMID: 30811371

Wei J, Shufelt C, Oestreicher Stock E, Mills C, Dhawan S, Jacob R, Torbati T, Cook-Wiens G, Benowitz N, Jacob P, Ganz P, Bairey Merz CN, Redberg R. Vascular Aging is Accelerated in Flight Attendants with Occupational Secondhand Smoke Exposure. Journal of occupational and environmental medicine 2018. PMID: 30475308

El-Boraie A, Taghavi T, Chenoweth MJ, Fukunaga K, Mushiroda T, Kubo M, Lerman C, Nollen NL, Benowitz NL, Tyndale RF. Evaluation of a weighted genetic risk score for the prediction of biomarkers of CYP2A6 activity. Addiction biology 2019. PMID: 30815984

Goodnough R, Nomura M, Badea A, Lynch KL, Benowitz NL, Tsutaoka B. Loperamide associated torsades de pointes, in the setting of complete heart block at marginally supratherapeutic dosing (20mg/day). Clinical toxicology (Philadelphia, Pa.) 2019. PMID: 30777457

Liakoni E, Gugelmann H, Dempsey DA, Wiegand TJ, Havel C, Jacob P, Benowitz NL. Butanediol Conversion to Gamma-Hydroxybutyrate Markedly Reduced by the Alcohol Dehydrogenase Blocker Fomepizole. Clinical pharmacology and therapeutics 2018. PMID: 30450642

Robinson JD, Li L, Chen M, Lerman C, Tyndale RF, Schnoll RA, Hawk LW, George TP, Benowitz NL, Cinciripini PM. Evaluating the temporal relationships between withdrawal symptoms and smoking relapse. Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors 2019. PMID: 30614717

Chen M, Carmella SG, Sipe C, Jensen J, Luo X, Le CT, Murphy SE, Benowitz NL, McClernon FJ, Vandrey R, Allen SS, Denlinger-Apte R, Cinciripini PM, Strasser AA, al'Absi M, Robinson JD, Donny EC, Hatsukami D, Hecht SS. Longitudinal stability in cigarette smokers of urinary biomarkers of exposure to the toxicants acrylonitrile and acrolein. PloS one 2019. PMID: 30608961

Benowitz NL. Managing Cannabis Use in Patients With Cardiovascular Disease. The Canadian journal of cardiology 2018. PMID: 30760417

Khachatoorian C, Jacob P, Sen A, Zhu Y, Benowitz NL, Talbot P. Identification and quantification of electronic cigarette exhaled aerosol residue chemicals in field sites. Environmental research 2018. PMID: 30623881

Kalkhoran S, Benowitz NL, Rigotti NA. Reprint of: Prevention and Treatment of Tobacco Use: JACC Health Promotion Series. Journal of the American College of Cardiology 2018. PMID: 30522631

Barua RS, Rigotti NA, Benowitz NL, Cummings KM, Jazayeri MA, Morris PB, Ratchford EV, Sarna L, Stecker EC, Wiggins BS. 2018 ACC Expert Consensus Decision Pathway on Tobacco Cessation Treatment: A Report of the American College of Cardiology Task Force on Clinical Expert Consensus Documents. Journal of the American College of Cardiology 2018. PMID: 30527452

Benowitz NL, Flanagan CA, Thomas TK, Koller KR, Wolfe AW, Renner CC, Hughes C, Decker PA, Hatsukami DK, Murphy NJ, Patten C. Urine 4-(methylnitrosamino)-1-(3) pyridyl-1-butanol and cotinine in Alaska native postpartum women and neonates comparing smokers and smokeless tobacco users. International journal of circumpolar health 2018. PMID: 30325719

Liakoni E, Edwards KC, St Helen G, Nardone N, Dempsey DA, Tyndale RF, Benowitz NL. Effects of Nicotine Metabolic Rate on Withdrawal Symptoms and Response to Cigarette Smoking After Abstinence. Clinical pharmacology and therapeutics 2018. PMID: 30242831

Patten CA, Koller KR, Flanagan CA, Hiratsuka VY, Hughes CA, Wolfe AW, Decker PA, Fruth K, Brockman TA, Korpela M, Gamez D, Bronars C, Murphy NJ, Hatsukami D, Benowitz NL, Thomas TK. Biomarker feedback intervention for smoking cessation among Alaska Native pregnant women: Randomized pilot study. Patient education and counseling 2018. PMID: 30391300

Liakoni E, Dempsey DA, Meyers M, Murphy NG, Fiorentino D, Havel C, Haller C, Benowitz NL. Effect of ?-hydroxybutyrate (GHB) on driving as measured by a driving simulator. Psychopharmacology 2018. PMID: 30232528

Hatsukami DK, Luo X, Jensen JA, al'Absi M, Allen SS, Carmella SG, Chen M, Cinciripini PM, Denlinger-Apte R, Drobes DJ, Koopmeiners JS, Lane T, Le CT, Leischow S, Luo K, McClernon FJ, Murphy SE, Paiano V, Robinson JD, Severson H, Sipe C, Strasser AA, Strayer LG, Tang MK, Vandrey R, Hecht SS, Benowitz NL, Donny EC. Effect of Immediate vs Gradual Reduction in Nicotine Content of Cigarettes on Biomarkers of Smoke Exposure: A Randomized Clinical Trial. JAMA 2018. PMID: 30193275

Khachatoorian C, Jacob Iii P, Benowitz NL, Talbot P. Electronic cigarette chemicals transfer from a vape shop to a nearby business in a multiple-tenant retail building. Tobacco control 2018. PMID: 30158206

St Helen G, Jacob Iii P, Nardone N, Benowitz NL. IQOS: examination of Philip Morris International's claim of reduced exposure. Tobacco control 2018. PMID: 30158205

Kalkhoran S, Benowitz NL, Rigotti NA. Prevention and Treatment of Tobacco Use: JACC Health Promotion Series. Journal of the American College of Cardiology 2018. PMID: 30139432

Mercincavage M, Lochbuehler K, Wileyto EP, Benowitz NL, Tyndale RF, Lerman C, Strasser AA. Association of Reduced Nicotine Content Cigarettes With Smoking Behaviors and Biomarkers of Exposure Among Slow and Fast Nicotine Metabolizers: A Nonrandomized Clinical Trial. JAMA network open 2018. PMID: 30627706

Cummings KM, Morris PB, Benowitz NL. Another Article About E-Cigarettes: Why Should I Care? Journal of the American Heart Association 2018. PMID: 30007935

Armenian P, Effron Z, Garbi N, Dirks R, Benowitz NL, Gerona RR. Stimulant drugs are associated with violent and penetrating trauma. The American journal of emergency medicine 2018. PMID: 30914133

Benowitz NL, Henningfield JE. Nicotine Reduction Strategy: State of the science and challenges to tobacco control policy and FDA tobacco product regulation. Preventive medicine 2018. PMID: 29944901

Neophytou AM, Oh SS, White MJ, Mak ACY, Hu D, Huntsman S, Eng C, Serebrisky D, Borrell LN, Farber HJ, Meade K, Davis A, Avila PC, Thyne SM, Rodríguez-Cintrón W, Rodríguez-Santana JR, Kumar R, Brigino-Buenaventura E, Sen S, Lenoir MA, Williams LK, Benowitz NL, Balmes JR, Eisen EA, Burchard EG. Secondhand smoke exposure and asthma outcomes among African-American and Latino children with asthma. Thorax 2018. PMID: 29899038

Fix BV, O'Connor RJ, Heckman BW, Benowitz N, Cummings MK, Fong GT, Thrasher JF. Response to "Rapid Nicotine Ratio and Successful Quitting: Acceptable Explanation" by the Authors of "Nicotine Metabolite Ratio (NMR) Prospectively Predicts Smoking Relapse: Longitudinal Findings from ITC Surveys in Five Countries". Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2018. PMID: 29878262

Prochaska JJ, Epperson A, Skan J, Oppezzo M, Barnett P, Delucchi K, Schnellbaecher M, Benowitz NL. The Healing and Empowering Alaskan Lives Toward Healthy-Hearts (HEALTHH) Project: Study protocol for a randomized controlled trial of an intervention for tobacco use and other cardiovascular risk behaviors for Alaska Native People. Contemporary clinical trials 2018. PMID: 29864548

Wang L, Bernert JT, Benowitz NL, Feng J, Jacob P, McGahee E, Caudill SP, Scherer G, Scherer M, Pluym N, Doig MV, Newland K, Murphy SE, Caron NJ, Sander LC, Shimizu M, Yamazaki H, Kim S, Langman LJ, Pritchett JS, Sniegoski LT, Li Y, Blount BC, Pirkle JL. Collaborative Method Performance Study of the Measurement of Nicotine, Its Metabolites, and Total Nicotine Equivalents in Human Urine. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2018. PMID: 29853481

St Helen G, Shahid M, Chu S, Benowitz NL. Impact of e-liquid flavors on e-cigarette vaping behavior. Drug and alcohol dependence 2018. PMID: 29879680

Benowitz NL, Pipe A, West R, Hays JT, Tonstad S, McRae T, Lawrence D, St Aubin L, Anthenelli RM. Cardiovascular Safety of Varenicline, Bupropion, and Nicotine Patch in Smokers: A Randomized Clinical Trial. JAMA internal medicine 2018. PMID: 29630702

West R, Evins AE, Benowitz NL, Russ C, McRae T, Lawrence D, St Aubin L, Krishen A, Maravic MC, Anthenelli RM. Factors associated with the efficacy of smoking cessation treatments and predictors of smoking abstinence in EAGLES. Addiction (Abingdon, England) 2018. PMID: 29508470

Smith TT, Hatsukami DK, Benowitz NL, Colby SM, McClernon FJ, Strasser AA, Tidey JW, White CM, Donny EC. Whether to push or pull? Nicotine reduction and non-combusted alternatives - Two strategies for reducing smoking and improving public health. Preventive medicine 2018. PMID: 29604326

Rubinstein ML, Delucchi K, Benowitz NL, Ramo DE. Adolescent Exposure to Toxic Volatile Organic Chemicals From E-Cigarettes. Pediatrics 2018. PMID: 29507165

Dermody SS, McClernon FJ, Benowitz N, Luo X, Tidey JW, Smith TT, Vandrey R, Hatsukami D, Donny EC. Effects of reduced nicotine content cigarettes on individual withdrawal symptoms over time and during abstinence. Experimental and clinical psychopharmacology 2018. PMID: 29504780

Panzer AR, Lynch SV, Langelier C, Christie JD, McCauley K, Nelson M, Cheung CK, Benowitz NL, Cohen MJ, Calfee CS. Lung Microbiota is Related to Smoking Status and to Development of ARDS in Critically Ill Trauma Patients. Volume 197 of Issue 5. American journal of respiratory and critical care medicine 2017. PMID: 29035085

Hang B, Wang Y, Huang Y, Wang P, Langley SA, Bi L, Sarker AH, Schick SF, Havel C, Jacob P, Benowitz N, Destaillats H, Tang X, Xia Y, Jen KY, Gundel LA, Mao JH, Snijders AM. Short-term early exposure to thirdhand cigarette smoke increases lung cancer incidence in mice. Clinical science (London, England : 1979) 2018. PMID: 29440622

Benowitz NL, Nardone N, Jain S, Dempsey DA, Addo N, St Helen G, Jacob P. Comparison of Urine 4-(Methylnitrosamino)-1-(3)Pyridyl-1-Butanol and Cotinine for Assessment of Active and Passive Smoke Exposure in Urban Adolescents. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2018. PMID: 29475963

Pulvers K, Emami AS, Nollen NL, Romero DR, Strong DR, Benowitz NL, Ahluwalia JS. Tobacco Consumption and Toxicant Exposure of Cigarette Smokers Using Electronic Cigarettes. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2018. PMID: 28003511

Song MA, Benowitz NL, Berman M, Brasky TM, Cummings KM, Hatsukami DK, Marian C, O'Connor R, Rees VW, Woroszylo C, Shields PG. Cigarette Filter Ventilation and its Relationship to Increasing Rates of Lung Adenocarcinoma. Journal of the National Cancer Institute 2017. PMID: 28525914

Kosmider L, Delijewski M, Koszowski B, Sobczak A, Benowitz NL, Goniewicz ML. Slower nicotine metabolism among postmenopausal Polish smokers. Pharmacological reports : PR 2017. PMID: 29627689

Chenoweth MJ, Ware JJ, Zhu AZX, Cole CB, Cox LS, Nollen N, Ahluwalia JS, Benowitz NL, Schnoll RA, Hawk LW, Cinciripini PM, George TP, Lerman C, Knight J, Tyndale RF. Genome-wide association study of a nicotine metabolism biomarker in African American smokers: impact of chromosome 19 genetic influences. Addiction (Abingdon, England) 2017. PMID: 28921760

Havel CM, Benowitz NL, Jacob P, St Helen G. An Electronic Cigarette Vaping Machine for the Characterization of Aerosol Delivery and Composition. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2017. PMID: 27281605

Fix BV, O'Connor RJ, Benowitz N, Heckman BW, Cummings KM, Fong GT, Thrasher JF. Nicotine Metabolite Ratio (NMR) Prospectively Predicts Smoking Relapse: Longitudinal Findings From ITC Surveys in Five Countries. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2017. PMID: 28387850

Benowitz NL, Jain S, Dempsey DA, Nardone N, Helen GS, Jacob P. Urine Cotinine Screening Detects Nearly Ubiquitous Tobacco Smoke Exposure in Urban Adolescents. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2017. PMID: 28031377

Nollen NL, Mayo MS, Clark L, Cox LS, Khariwala SS, Pulvers K, Benowitz NL, Ahluwalia JS. Tobacco toxicant exposure in cigarette smokers who use or do not use other tobacco products. Drug and alcohol dependence 2017. PMID: 28843083

Benowitz NL. Comprehensive Nicotine Regulation to End the Combustible Tobacco Epidemic. Annals of internal medicine 2017. PMID: 28806818

Logue JM, Sleiman M, Montesinos VN, Russell ML, Litter MI, Benowitz NL, Gundel LA, Destaillats H. Emissions from Electronic Cigarettes: Assessing Vapers' Intake of Toxic Compounds, Secondhand Exposures, and the Associated Health Impacts. Environmental science & technology 2017. PMID: 28766331

Kassem NOF, Kassem NO, Liles S, Jackson SR, Chatfield DA, Jacob P, Benowitz NL, Hovell MF. Urinary NNAL in hookah smokers and non-smokers after attending a hookah social event in a hookah lounge or a private home. Regulatory toxicology and pharmacology : RTP 2017. PMID: 28716579

Peng AR, Morales M, Wileyto EP, Hawk LW, Cinciripini P, George TP, Benowitz NL, Nollen NL, Lerman C, Tyndale RF, Schnoll R. Measures and predictors of varenicline adherence in the treatment of nicotine dependence. Addictive behaviors 2017. PMID: 28728040

St Helen G, Dempsey DA, Havel CM, Jacob P, Benowitz NL. Impact of e-liquid flavors on nicotine intake and pharmacology of e-cigarettes. Drug and alcohol dependence 2017. PMID: 28704768

Gubner NR, Guydish J, Humfleet GL, Benowitz NL, Hall SM. Nicotine biomarkers and rate of nicotine metabolism among cigarette smokers taking buprenorphine for opioid dependency. Drug and alcohol dependence 2017. PMID: 28683421

Schick SF, Blount BC, Jacob P, Saliba NA, Bernert JT, El Hellani A, Jatlow P, Pappas RS, Wang L, Foulds J, Ghosh A, Hecht SS, Gomez JC, Martin JR, Mesaros C, Srivastava S, St Helen G, Tarran R, Lorkiewicz PK, Blair IA, Kimmel HL, Doerschuk CM, Benowitz NL, Bhatnagar A. Biomarkers of exposure to new and emerging tobacco delivery products. American journal of physiology. Lung cellular and molecular physiology 2017. PMID: 28522563

Taghavi T, St Helen G, Benowitz NL, Tyndale RF. Effect of UGT2B10, UGT2B17, FMO3, and OCT2 genetic variation on nicotine and cotinine pharmacokinetics and smoking in African Americans. Pharmacogenetics and genomics 2017. PMID: 28178031

Benowitz NL, Fraiman JB. Cardiovascular effects of electronic cigarettes. Nature reviews. Cardiology 2017. PMID: 28332500

Weinstein JR, Asteria-Peñaloza R, Diaz-Artiga A, Davila G, Hammond SK, Ryde IT, Meyer JN, Benowitz N, Thompson LM. Exposure to polycyclic aromatic hydrocarbons and volatile organic compounds among recently pregnant rural Guatemalan women cooking and heating with solid fuels. International journal of hygiene and environmental health 2017. PMID: 28320639

Hang B, Snijders AM, Huang Y, Schick SF, Wang P, Xia Y, Havel C, Jacob P, Benowitz N, Destaillats H, Gundel LA, Mao JH. Early exposure to thirdhand cigarette smoke affects body mass and the development of immunity in mice. Scientific Reports 2017. PMID: 28157226

Jacob P, Benowitz NL, Destaillats H, Gundel L, Hang B, Martins-Green M, Matt GE, Quintana PJ, Samet JM, Schick SF, Talbot P, Aquilina NJ, Hovell MF, Mao JH, Whitehead TP. Thirdhand Smoke: New Evidence, Challenges, and Future Directions. Chemical research in toxicology 2016. PMID: 28001376

Vo KT, Horng H, Smollin CG, Benowitz NL. Severe Carisoprodol Withdrawal After a 14-Year Addiction and Acute Overdose. The Journal of emergency medicine 2016. PMID: 27979642

Rupprecht LE, Koopmeiners JS, Dermody SS, Oliver JA, al'Absi M, Benowitz NL, Denlinger-Apte R, Drobes DJ, Hatsukami D, McClernon FJ, Pacek LR, Smith TT, Sved AF, Tidey J, Vandrey R, Donny EC. Reducing nicotine exposure results in weight gain in smokers randomised to very low nicotine content cigarettes. Tobacco control 2016. PMID: 27856940

Bronars C, Patten C, Koller K, Hatsukami D, Flanagan CA, Decker PA, Hanson A, Wolfe A, Hughes C, Benowitz N, Murphy NJ, Thomas T. Perceived risks and reasons to smoke cigarettes during pregnancy among Alaska native women. Ethnicity & health 2016. PMID: 27842438

Shields PG, Herbst RS, Arenberg D, Benowitz NL, Bierut L, Luckart JB, Cinciripini P, Collins B, David S, Davis J, Hitsman B, Hyland A, Lang M, Leischow S, Park ER, Purcell WT, Selzle J, Silber A, Spencer S, Tanvetyanon T, Tiep B, Tindle HA, Tucker-Seeley R, Urbanic J, Hooper MW, Weksler B, Whitlock CW, Wood DE, Burns J, Scavone J. Smoking Cessation, Version 1.2016, NCCN Clinical Practice Guidelines in Oncology. Journal of the National Comprehensive Cancer Network : JNCCN 2016. PMID: 27799513

St Helen G, Ross KC, Dempsey DA, Havel CM, Jacob P, Benowitz NL. Nicotine Delivery and Vaping Behavior During ad Libitum E-cigarette Access. Tobacco regulatory science 2016. PMID: 28393086

Strasser AA, Souprountchouk V, Kaufmann A, Blazekovic S, Leone F, Benowitz NL, Schnoll RA. Nicotine Replacement, Topography, and Smoking Phenotypes of E-cigarettes. Tobacco regulatory science 2016. PMID: 27942543

Brown-Johnson CG, Oppezzo M, Benowitz NL, Prochaska JJ. "You have the right to protect your health": Perceptions of Secondhand Smoke and Exposure Mitigation Strategies in Low-Income Patients With Heart Disease, San Francisco, 2011-2012. Preventing chronic disease 2016. PMID: 27560724

Benowitz NL, Donny EC, Hatsukami DK. Reduced nicotine content cigarettes, e-cigarettes and the cigarette end game. Addiction (Abingdon, England) 2016. PMID: 27555354

Goniewicz ML, Gawron M, Smith DM, Peng M, Jacob P, Benowitz NL. Exposure to Nicotine and Selected Toxicants in Cigarette Smokers Who Switched to Electronic Cigarettes: A Longitudinal Within-Subjects Observational Study. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2016. PMID: 27613896

Tidey JW, Pacek LR, Koopmeiners JS, Vandrey R, Nardone N, Drobes DJ, Benowitz NL, Dermody SS, Lemieux A, Denlinger RL, Cassidy R, al'Absi M, Hatsukami DK, Donny EC. Effects of 6-Week Use of Reduced-Nicotine Content Cigarettes in Smokers With and Without Elevated Depressive Symptoms. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2016. PMID: 27613885

Nardone N, Donny EC, Hatsukami DK, Koopmeiners JS, Murphy SE, Strasser AA, Tidey JW, Vandrey R, Benowitz NL. Estimations and predictors of non-compliance in switchers to reduced nicotine content cigarettes. Addiction (Abingdon, England) 2016. PMID: 27367436

Benowitz NL, St Helen G, Dempsey DA, Jacob P, Tyndale RF. Disposition kinetics and metabolism of nicotine and cotinine in African American smokers: impact of CYP2A6 genetic variation and enzymatic activity. Pharmacogenetics and genomics 2016. PMID: 27035242

Martin EM, Clapp PW, Rebuli ME, Pawlak EA, Glista-Baker E, Benowitz NL, Fry RC, Jaspers I. E-cigarette use results in suppression of immune and inflammatory-response genes in nasal epithelial cells similar to cigarette smoke. American journal of physiology. Lung cellular and molecular physiology 2016. PMID: 27288488

Flanagan CA, Koller KR, Wolfe AW, Thomas TK, Benowitz NL, Renner CC, Hughes C, Hatsukami DK, Bronars C, Murphy NJ, Day G, Decker PA, Patten CA. Fetal Exposure to Carcinogens With Tobacco Use in Pregnancy: Phase 1 MAW Study Findings. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2016. PMID: 27190400

Ross KC, Gubner NR, Tyndale RF, Hawk LW, Lerman C, George TP, Cinciripini P, Schnoll RA, Benowitz NL. Racial differences in the relationship between rate of nicotine metabolism and nicotine intake from cigarette smoking. Pharmacology, biochemistry, and behavior 2016. PMID: 27180107

Baurley JW, Edlund CK, Pardamean CI, Conti DV, Krasnow R, Javitz HS, Hops H, Swan GE, Benowitz NL, Bergen AW. Genome-Wide Association of the Laboratory-Based Nicotine Metabolite Ratio in Three Ancestries. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2016. PMID: 27113016

Anthenelli RM, Benowitz NL, West R, St Aubin L, McRae T, Lawrence D, Ascher J, Russ C, Krishen A, Evins AE. Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial. Lancet (London, England) 2016. PMID: 27116918

Gubner NR, Kozar-Konieczna A, Szoltysek-Boldys I, Slodczyk-Mankowska E, Goniewicz J, Sobczak A, Jacob P, Benowitz NL, Goniewicz ML. Cessation of alcohol consumption decreases rate of nicotine metabolism in male alcohol-dependent smokers. Drug and alcohol dependence 2016. PMID: 27107849

Denlinger RL, Smith TT, Murphy SE, Koopmeiners JS, Benowitz NL, Hatsukami DK, Pacek LR, Colino C, Cwalina SN, Donny EC. Nicotine and Anatabine Exposure from Very Low Nicotine Content Cigarettes. Tobacco regulatory science 2016. PMID: 29600258

Ross KC, Dempsey DA, St Helen G, Delucchi K, Benowitz NL. The Influence of Puff Characteristics, Nicotine Dependence, and Rate of Nicotine Metabolism on Daily Nicotine Exposure in African American Smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2016. PMID: 27030603

Nelson MD, Rezk-Hanna M, Rader F, Mason OR, Tang X, Shidban S, Rosenberry R, Benowitz NL, Tashkin DP, Elashoff RM, Lindner JR, Victor RG. Acute Effect of Hookah Smoking on the Human Coronary Microcirculation. The American journal of cardiology 2016. PMID: 27067622

Benowitz NL, Burbank AD. Cardiovascular toxicity of nicotine: Implications for electronic cigarette use. Trends in cardiovascular medicine 2016. PMID: 27079891

Brondfield M, Wu L, Benowitz N. Minoxidil-Associated Pleuropericardial Effusion. Journal of general internal medicine 2016. PMID: 26951281

Northrup TF, Jacob P, Benowitz NL, Hoh E, Quintana PJ, Hovell MF, Matt GE, Stotts AL. Thirdhand Smoke: State of the Science and a Call for Policy Expansion. Public health reports (Washington, D.C. : 1974) 2016. PMID: 26957657

Nollen NL, Cox LS, Yu Q, Ellerbeck EF, Scheuermann TS, Benowitz NL, Tyndale RF, Mayo MS, Ahluwalia JS. A clinical trial to examine disparities in quitting between African-American and White adult smokers: Design, accrual, and baseline characteristics. Contemporary clinical trials 2015. PMID: 26667382

Northrup TF, Khan AM, Jacob P, Benowitz NL, Hoh E, Hovell MF, Matt GE, Stotts AL. Thirdhand smoke contamination in hospital settings: assessing exposure risk for vulnerable paediatric patients. Tobacco control 2015. PMID: 26635031

St Helen G, Havel C, Dempsey DA, Jacob P, Benowitz NL. Nicotine delivery, retention and pharmacokinetics from various electronic cigarettes. Addiction (Abingdon, England) 2015. PMID: 26430813

Donny EC, Denlinger RL, Tidey JW, Koopmeiners JS, Benowitz NL, Vandrey RG, al'Absi M, Carmella SG, Cinciripini PM, Dermody SS, Drobes DJ, Hecht SS, Jensen J, Lane T, Le CT, McClernon FJ, Montoya ID, Murphy SE, Robinson JD, Stitzer ML, Strasser AA, Tindle H, Hatsukami DK. Randomized Trial of Reduced-Nicotine Standards for Cigarettes. The New England journal of medicine 2015. PMID: 26422724

Morris PB, Ference BA, Jahangir E, Feldman DN, Ryan JJ, Bahrami H, El-Chami MF, Bhakta S, Winchester DE, Al-Mallah MH, Sanchez Shields M, Deedwania P, Mehta LS, Phan BA, Benowitz NL. Cardiovascular Effects of Exposure to Cigarette Smoke and Electronic Cigarettes: Clinical Perspectives From the Prevention of Cardiovascular Disease Section Leadership Council and Early Career Councils of the American College of Cardiology. Journal of the American College of Cardiology 2015. PMID: 26383726

Calfee CS, Matthay MA, Kangelaris KN, Siew ED, Janz DR, Bernard GR, May AK, Jacob P, Havel C, Benowitz NL, Ware LB. Cigarette Smoke Exposure and the Acute Respiratory Distress Syndrome. Critical care medicine 2015. PMID: 26010690

Prochaska JJ, Benowitz NL. Smoking cessation and the cardiovascular patient. Current opinion in cardiology 2015. PMID: 26196657

Prochaska JJ, Benowitz NL. The Past, Present, and Future of Nicotine Addiction Therapy. Annual review of medicine 2015. PMID: 26332005

Benowitz NL, Nardone N, Dains KM, Hall SM, Stewart S, Dempsey D, Jacob P. Effect of reducing the nicotine content of cigarettes on cigarette smoking behavior and tobacco smoke toxicant exposure: 2-year follow up. Addiction (Abingdon, England) 2015. PMID: 26198394

Bergen AW, Michel M, Nishita D, Krasnow R, Javitz HS, Conneely KN, Lessov-Schlaggar CN, Hops H, Zhu AZ, Baurley JW, McClure JB, Hall SM, Baker TB, Conti DV, Benowitz NL, Lerman C, Tyndale RF, Swan GE. Drug Metabolizing Enzyme and Transporter Gene Variation, Nicotine Metabolism, Prospective Abstinence, and Cigarette Consumption. PloS one 2015. PMID: 26132489

Tyndale RF, Zhu AZ, George TP, Cinciripini P, Hawk LW, Schnoll RA, Swan GE, Benowitz NL, Heitjan DF, Lerman C. Lack of Associations of CHRNA5-A3-B4 Genetic Variants with Smoking Cessation Treatment Outcomes in Caucasian Smokers despite Associations with Baseline Smoking. PloS one 2015. PMID: 26010901

Tanner JA, Novalen M, Jatlow P, Huestis MA, Murphy SE, Kaprio J, Kankaanpää A, Galanti L, Stefan C, George TP, Benowitz NL, Lerman C, Tyndale RF. Nicotine metabolite ratio (3-hydroxycotinine/cotinine) in plasma and urine by different analytical methods and laboratories: implications for clinical implementation. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2015. PMID: 26014804

Ebbert JO, Severson HH, Danaher BG, Benowitz NL, Schroeder DR. Nicotine Metabolite Ratio Is Associated With Lozenge Use But Not Quitting in Smokeless Tobacco Users. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2015. PMID: 25977408

Zhu AZ, Cox LS, Ahluwalia JS, Renner CC, Hatsukami DK, Benowitz NL, Tyndale RF. Genetic and phenotypic variation in UGT2B17, a testosterone-metabolizing enzyme, is associated with BMI in males. Pharmacogenetics and genomics 2015. PMID: 25794161

Whitehead TP, Havel C, Metayer C, Benowitz NL, Jacob P. Tobacco alkaloids and tobacco-specific nitrosamines in dust from homes of smokeless tobacco users, active smokers, and nontobacco users. Chemical research in toxicology 2015. PMID: 25794360

Whitsel LP, Benowitz N, Bhatnagar A, Bullen C, Goldstein F, Matthias-Gray L, Grossmeier J, Harris J, Isaac F, Loeppke R, Manley M, Moseley K, Niemiec T, O'Brien V, Palma-Davis L, Pronk N, Pshock J, Stave GM, Terry P. Guidance to employers on integrating e-cigarettes/electronic nicotine delivery systems into tobacco worksite policy. Journal of occupational and environmental medicine 2015. PMID: 25742539

Grana R, Benowitz N, Glantz S. Response to letter regarding article, "Electronic cigarettes: a scientific review". Volume 131 of Issue 6. Circulation 2015. PMID: 25815391

Lerman C, Schnoll RA, Hawk LW, Cinciripini P, George TP, Wileyto EP, Swan GE, Benowitz NL, Heitjan DF, Tyndale RF. Use of the nicotine metabolite ratio as a genetically informed biomarker of response to nicotine patch or varenicline for smoking cessation: a randomised, double-blind placebo-controlled trial. The Lancet. Respiratory medicine 2015. PMID: 25588294

Bandiera FC, Ross KC, Taghavi S, Delucchi K, Tyndale RF, Benowitz NL. Nicotine Dependence, Nicotine Metabolism, and the Extent of Compensation in Response to Reduced Nicotine Content Cigarettes. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2015. PMID: 25555385

Japuntich SJ, Eilers MA, Shenhav S, Park ER, Winickoff JP, Benowitz NL, Rigotti NA. Secondhand tobacco smoke exposure among hospitalized nonsmokers with coronary heart disease. JAMA internal medicine 2015. PMID: 25383761

Benowitz NL, Gan Q, Goniewicz ML, Lu W, Xu J, Li X, Jacob P, Glantz S. Different profiles of carcinogen exposure in Chinese compared with US cigarette smokers. Volume 24 of Issue e4. Tobacco control 2014. PMID: 25535294

Hatsukami DK, Donny EC, Koopmeiners JS, Benowitz NL. Compensatory smoking from gradual and immediate reduction in cigarette nicotine content. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2014. PMID: 25515551

Benowitz NL, Nardone N, Hatsukami DK, Donny EC. Biochemical estimation of noncompliance with smoking of very low nicotine content cigarettes. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2014. PMID: 25416718

St Helen G, Jacob P, Peng M, Dempsey DA, Hammond SK, Benowitz NL. Intake of toxic and carcinogenic volatile organic compounds from secondhand smoke in motor vehicles. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2014. PMID: 25398951

Al-Abri S, Meier KH, Colby JM, Smollin CG, Benowitz NL. Cardiogenic shock after use of fluoroamphetamine confirmed with serum and urine levels. Clinical toxicology (Philadelphia, Pa.) 2014. PMID: 25350468

Wassenaar CA, Conti DV, Das S, Chen P, Cook EH, Ratain MJ, Benowitz NL, Tyndale RF. UGT1A and UGT2B genetic variation alters nicotine and nitrosamine glucuronidation in european and african american smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2014. PMID: 25277794

Zhu AZ, Zhou Q, Cox LS, Ahluwalia JS, Benowitz NL, Tyndale RF. Gene variants in CYP2C19 are associated with altered in vivo bupropion pharmacokinetics but not bupropion-assisted smoking cessation outcomes. Drug metabolism and disposition: the biological fate of chemicals 2014. PMID: 25187485

Hsieh SJ, Zhuo H, Benowitz NL, Thompson BT, Liu KD, Matthay MA, Calfee CS. Prevalence and impact of active and passive cigarette smoking in acute respiratory distress syndrome. Critical care medicine 2014. PMID: 24942512

Bhatnagar A, Whitsel LP, Ribisl KM, Bullen C, Chaloupka F, Piano MR, Robertson RM, McAuley T, Goff D, Benowitz N. Electronic cigarettes: a policy statement from the American Heart Association. Circulation 2014. PMID: 25156991

Bergen AW, Javitz HS, Krasnow R, Michel M, Nishita D, Conti DV, Edlund CK, Kwok PY, McClure JB, Kim RB, Hall SM, Tyndale RF, Baker TB, Benowitz NL, Swan GE. Organic cation transporter variation and response to smoking cessation therapies. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2014. PMID: 25143296

Hajek P, Etter JF, Benowitz N, Eissenberg T, McRobbie H. Electronic cigarettes: review of use, content, safety, effects on smokers and potential for harm and benefit. Addiction (Abingdon, England) 2014. PMID: 25078252

Donny EC, Hatsukami DK, Benowitz NL, Sved AF, Tidey JW, Cassidy RN. Reduced nicotine product standards for combustible tobacco: building an empirical basis for effective regulation. Preventive medicine 2014. PMID: 24967958

St Helen G, Benowitz NL, Dains KM, Havel C, Peng M, Jacob P. Nicotine and carcinogen exposure after water pipe smoking in hookah bars. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2014. PMID: 24836469

Grana R, Benowitz N, Glantz SA. E-cigarettes: a scientific review. Volume 129 of Issue 19. Circulation 2014. PMID: 24821826

Grana RA, Ling PM, Benowitz N, Glantz S. Electronic cigarettes. Cardiology patient page. Volume 129 of Issue 19. Circulation 2014. PMID: 24821830

Shiffman S, Dunbar MS, Benowitz NL. A comparison of nicotine biomarkers and smoking patterns in daily and nondaily smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2014. PMID: 24740202

Zhu AZ, Zhou Q, Cox LS, David SP, Ahluwalia JS, Benowitz NL, Tyndale RF. Association of CHRNA5-A3-B4 SNP rs2036527 with smoking cessation therapy response in African-American smokers. Clinical pharmacology and therapeutics 2014. PMID: 24733007

Kassem NO, Daffa RM, Liles S, Jackson SR, Kassem NO, Younis MA, Mehta S, Chen M, Jacob P, Carmella SG, Chatfield DA, Benowitz NL, Matt GE, Hecht SS, Hovell MF. Children's exposure to secondhand and thirdhand smoke carcinogens and toxicants in homes of hookah smokers. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2014. PMID: 24590387

Chenoweth MJ, Zhu AZ, Sanderson Cox L, Ahluwalia JS, Benowitz NL, Tyndale RF. Variation in P450 oxidoreductase (POR) A503V and flavin-containing monooxygenase (FMO)-3 E158K is associated with minor alterations in nicotine metabolism, but does not alter cigarette consumption. Pharmacogenetics and genomics 2014. PMID: 24448396

Benowitz NL. Emerging nicotine delivery products. Implications for public health. Annals of the American Thoracic Society 2014. PMID: 24575992

Piliguian M, Zhu AZ, Zhou Q, Benowitz NL, Ahluwalia JS, Sanderson Cox L, Tyndale RF. Novel CYP2A6 variants identified in African Americans are associated with slow nicotine metabolism in vitro and in vivo. Pharmacogenetics and genomics 2014. PMID: 24305170

Martins-Green M, Adhami N, Frankos M, Valdez M, Goodwin B, Lyubovitsky J, Dhall S, Garcia M, Egiebor I, Martinez B, Green HW, Havel C, Yu L, Liles S, Matt G, Destaillats H, Sleiman M, Gundel LA, Benowitz N, Jacob P, Hovell M, Winickoff JP, Curras-Collazo M. Cigarette smoke toxins deposited on surfaces: implications for human health. PloS one 2014. PMID: 24489722

Prochaska JJ, Fromont SC, Delucchi K, Young-Wolff KC, Benowitz NL, Hall S, Bonas T, Hall SM. Multiple risk-behavior profiles of smokers with serious mental illness and motivation for change. Health psychology : official journal of the Division of Health Psychology, American Psychological Association 2014. PMID: 24467257

Hendricks PS, Delucchi KL, Benowitz NL, Hall SM. Clinical significance of early smoking withdrawal effects and their relationships with nicotine metabolism: preliminary results from a pilot study. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2013. PMID: 24353342

Khariwala SS, Scheuermann TS, Berg CJ, Hayes RB, Nollen NL, Thomas JL, Guo H, Ahluwalia JS, Benowitz NL. Cotinine and tobacco-specific carcinogen exposure among nondaily smokers in a multiethnic sample. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2013. PMID: 24297808

Nollen NL, Mayo MS, Ahluwalia JS, Tyndale RF, Benowitz NL, Faseru B, Buchanan TS, Cox LS. Factors associated with discontinuation of bupropion and counseling among African American light smokers in a randomized clinical trial. Annals of behavioral medicine : a publication of the Society of Behavioral Medicine 2013. PMID: 23733379

Al-Abri SA, Orengo JP, Hayashi S, Thoren KL, Benowitz NL, Olson KR. Delayed bupropion cardiotoxicity associated with elevated serum concentrations of bupropion but not hydroxybupropion. Clinical toxicology (Philadelphia, Pa.) 2013. PMID: 24131328

Jacob P, Goniewicz ML, Havel CM, Schick SF, Benowitz NL. Nicotelline: a proposed biomarker and environmental tracer for particulate matter derived from tobacco smoke. Chemical research in toxicology 2013. PMID: 24125094

Yang J, Pearl M, Jacob P, DeLorenze GN, Benowitz NL, Yu L, Havel C, Kharrazi M. Levels of cotinine in dried blood specimens from newborns as a biomarker of maternal smoking close to the time of delivery. American journal of epidemiology 2013. PMID: 24068198

David SP, Strong DR, Leventhal AM, Lancaster MA, McGeary JE, Munafò MR, Bergen AW, Swan GE, Benowitz NL, Tyndale RF, Conti DV, Brown RA, Lerman C, Niaura R. Influence of a dopamine pathway additive genetic efficacy score on smoking cessation: results from two randomized clinical trials of bupropion. Addiction (Abingdon, England) 2013. PMID: 23941313

Prochaska JJ, Grossman W, Young-Wolff KC, Benowitz NL. Validity of self-reported adult secondhand smoke exposure. Volume 24 of Issue 1. Tobacco control 2013. PMID: 23997071

Prochaska JJ, Das S, Benowitz NL. Cytisine, the world's oldest smoking cessation aid. BMJ (Clinical research ed.) 2013. PMID: 23974638

Benowitz NL, Goniewicz ML. The regulatory challenge of electronic cigarettes. JAMA 2013. PMID: 23856948

Dempsey DA, St Helen G, Jacob P, Tyndale RF, Benowitz NL. Genetic and pharmacokinetic determinants of response to transdermal nicotine in white, black, and Asian nonsmokers. Clinical pharmacology and therapeutics 2013. PMID: 23933970

Zhu AZ, Zhou Q, Cox LS, Ahluwalia JS, Benowitz NL, Tyndale RF. Variation in trans-3'-hydroxycotinine glucuronidation does not alter the nicotine metabolite ratio or nicotine intake. PloS one 2013. PMID: 23936477

Zhu AZ, Renner CC, Hatsukami DK, Benowitz NL, Tyndale RF. CHRNA5-A3-B4 genetic variants alter nicotine intake and interact with tobacco use to influence body weight in Alaska Native tobacco users. Addiction (Abingdon, England) 2013. PMID: 23692359

Dempsey DA, Sambol NC, Jacob P, Hoffmann E, Tyndale RF, Fuentes-Afflick E, Benowitz NL. CYP2A6 genotype but not age determines cotinine half-life in infants and children. Clinical pharmacology and therapeutics 2013. PMID: 23714690

St Helen G, Jacob P, Benowitz NL. Stability of the nicotine metabolite ratio in smokers of progressively reduced nicotine content cigarettes. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2013. PMID: 23674838

Benowitz NL, Henningfield JE. Reducing the nicotine content to make cigarettes less addictive. Tobacco control 2013. PMID: 23591498

Goniewicz ML, Knysak J, Gawron M, Kosmider L, Sobczak A, Kurek J, Prokopowicz A, Jablonska-Czapla M, Rosik-Dulewska C, Havel C, Jacob P, Benowitz N. Levels of selected carcinogens and toxicants in vapour from electronic cigarettes. Tobacco control 2013. PMID: 23467656

Jacob P, Abu Raddaha AH, Dempsey D, Havel C, Peng M, Yu L, Benowitz NL. Comparison of nicotine and carcinogen exposure with water pipe and cigarette smoking. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2013. PMID: 23462922

Benowitz NL, Zhu AZ, Tyndale RF, Dempsey D, Jacob P. Influence of CYP2B6 genetic variants on plasma and urine concentrations of bupropion and metabolites at steady state. Pharmacogenetics and genomics 2013. PMID: 23344581

Benowitz NL, Prochaska JJ. Smoking cessation after acute myocardial infarction. Journal of the American College of Cardiology 2013. PMID: 23369418

Bergen AW, Javitz HS, Krasnow R, Nishita D, Michel M, Conti DV, Liu J, Lee W, Edlund CK, Hall S, Kwok PY, Benowitz NL, Baker TB, Tyndale RF, Lerman C, Swan GE. Nicotinic acetylcholine receptor variation and response to smoking cessation therapies. Pharmacogenetics and genomics 2013. PMID: 23249876

Zhu AZ, Renner CC, Hatsukami DK, Swan GE, Lerman C, Benowitz NL, Tyndale RF. The ability of plasma cotinine to predict nicotine and carcinogen exposure is altered by differences in CYP2A6: the influence of genetics, race, and sex. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2013. PMID: 23371292

Jones IA, St Helen G, Meyers MJ, Dempsey DA, Havel C, Jacob P, Northcross A, Hammond SK, Benowitz NL. Biomarkers of secondhand smoke exposure in automobiles. Tobacco control 2013. PMID: 23349229

Benowitz NL, Dempsey D, Tyndale RF, St Helen G, Jacob P. Dose-independent kinetics with low level exposure to nicotine and cotinine. British journal of clinical pharmacology 2013. PMID: 22574797

Rubinstein ML, Shiffman S, Rait MA, Benowitz NL. Race, gender, and nicotine metabolism in adolescent smokers. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2012. PMID: 23239845

Bergen AW, Javitz HS, Su L, He Y, Conti DV, Benowitz NL, Tyndale RF, Lerman C, Swan GE. The DRD4 exon III VNTR, bupropion, and associations with prospective abstinence. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2012. PMID: 23212438

Faseru B, Nollen NL, Mayo MS, Krebill R, Choi WS, Benowitz NL, Tyndale RF, Okuyemi KS, Ahluwalia JS, Sanderson Cox L. Predictors of cessation in African American light smokers enrolled in a bupropion clinical trial. Addictive behaviors 2012. PMID: 23254230

Northcross AL, Trinh M, Kim J, Jones IA, Meyers MJ, Dempsey DD, Benowitz NL, Hammond SK. Particulate mass and polycyclic aromatic hydrocarbons exposure from secondhand smoke in the back seat of a vehicle. Tobacco control 2012. PMID: 23172398

Zhu AZ, Cox LS, Nollen N, Faseru B, Okuyemi KS, Ahluwalia JS, Benowitz NL, Tyndale RF. CYP2B6 and bupropion's smoking-cessation pharmacology: the role of hydroxybupropion. Clinical pharmacology and therapeutics 2012. PMID: 23149928

Repace J, Zhang B, Bondy SJ, Benowitz N, Ferrence R. Air quality, mortality, and economic benefits of a smoke - free workplace law for non-smoking Ontario bar workers. Indoor air 2012. PMID: 23006034

St Helen G, Dempsey D, Wilson M, Jacob P, Benowitz NL. Racial differences in the relationship between tobacco dependence and nicotine and carcinogen exposure. Addiction (Abingdon, England) 2012. PMID: 22971134

Hatsukami DK, Benowitz NL, Donny E, Henningfield J, Zeller M. Nicotine reduction: strategic research plan. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2012. PMID: 23100460

Berg CJ, Schauer GL, Ahluwalia JS, Benowitz NL. Correlates of NNAL levels among nondaily and daily smokers in the college student population. Current biomarker findings 2012. PMID: 24298447

Rubinstein ML, Shiffman S, Moscicki AB, Rait MA, Sen S, Benowitz NL. Nicotine metabolism and addiction among adolescent smokers. Addiction (Abingdon, England) 2012. PMID: 22823143

Zhu AZ, Binnington MJ, Renner CC, Lanier AP, Hatsukami DK, Stepanov I, Watson CH, Sosnoff CS, Benowitz NL, Tyndale RF. Alaska Native smokers and smokeless tobacco users with slower CYP2A6 activity have lower tobacco consumption, lower tobacco-specific nitrosamine exposure and lower tobacco-specific nitrosamine bioactivation. Carcinogenesis 2012. PMID: 23027621

Renner CC, Lanier AP, Lindgren B, Jensen J, Patten CA, Parascandola M, Benowitz NL, Tyndale RF, Hatsukami DK. Tobacco use among southwestern Alaska Native people. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2012. PMID: 22949573

Avila-Tang E, Al-Delaimy WK, Ashley DL, Benowitz N, Bernert JT, Kim S, Samet JM, Hecht SS. Assessing secondhand smoke using biological markers. Tobacco control 2012. PMID: 22940677

Dempsey DA, Meyers MJ, Oh SS, Nguyen EA, Fuentes-Afflick E, Wu AH, Jacob P, Benowitz NL. Determination of tobacco smoke exposure by plasma cotinine levels in infants and children attending urban public hospital clinics. Archives of pediatrics & adolescent medicine 2012. PMID: 22566513

Williams JM, Gandhi KK, Lu SE, Steinberg ML, Benowitz NL. Nicotine intake and smoking topography in smokers with bipolar disorder. Bipolar disorders 2012. PMID: 22938167

Joel DL, Denlinger RL, Dermody SS, Hatsukami DK, Benowitz NL, Donny EC. Very low nicotine content cigarettes and potential consequences on cardiovascular disease. Current cardiovascular risk reports 2012. PMID: 23264843

Mozaffarian D, Afshin A, Benowitz NL, Bittner V, Daniels SR, Franch HA, Jacobs DR, Kraus WE, Kris-Etherton PM, Krummel DA, Popkin BM, Whitsel LP, Zakai NA. Population approaches to improve diet, physical activity, and smoking habits: a scientific statement from the American Heart Association. Circulation 2012. PMID: 22907934

Lee W, Ray R, Bergen AW, Swan GE, Thomas P, Tyndale RF, Benowitz NL, Lerman C, Conti DV. DRD1 associations with smoking abstinence across slow and normal nicotine metabolizers. Pharmacogenetics and genomics 2012. PMID: 22495174

Binnington MJ, Zhu AZ, Renner CC, Lanier AP, Hatsukami DK, Benowitz NL, Tyndale RF. CYP2A6 and CYP2B6 genetic variation and its association with nicotine metabolism in South Western Alaska Native people. Pharmacogenetics and genomics 2012. PMID: 22569203

Frey PF, Ganz P, Hsue PY, Benowitz NL, Glantz SA, Balmes JR, Schick SF. The exposure-dependent effects of aged secondhand smoke on endothelial function. Volume 59 of Issue 21. Journal of the American College of Cardiology 2012. PMID: 22595411

Schnoll RA, Wileyto EP, Leone FT, Tyndale RF, Benowitz NL. High dose transdermal nicotine for fast metabolizers of nicotine: a proof of concept placebo-controlled trial. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2012. PMID: 22589423

St Helen G, Novalen M, Heitjan DF, Dempsey D, Jacob P, Aziziyeh A, Wing VC, George TP, Tyndale RF, Benowitz NL. Reproducibility of the nicotine metabolite ratio in cigarette smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2012. PMID: 22552800

Benowitz NL, Renner CC, Lanier AP, Tyndale RF, Hatsukami DK, Lindgren B, Stepanov I, Watson CH, Sosnoff CS, Jacob P. Exposure to nicotine and carcinogens among Southwestern Alaskan Native cigarette smokers and smokeless tobacco users. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2012. PMID: 22490317

St Helen G, Goniewicz ML, Dempsey D, Wilson M, Jacob P, Benowitz NL. Exposure and kinetics of polycyclic aromatic hydrocarbons (PAHs) in cigarette smokers. Chemical research in toxicology 2012. PMID: 22428611

Buchanan TS, Berg CJ, Cox LS, Nazir N, Benowitz NL, Yu L, Yturralde O, Jacob P, Choi WS, Ahluwalia JS, Nollen NL. Adherence to varenicline among African American smokers: an exploratory analysis comparing plasma concentration, pill count, and self-report. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2012. PMID: 22367976

Benowitz NL, Dains KM, Hall SM, Stewart S, Wilson M, Dempsey D, Jacob P. Smoking behavior and exposure to tobacco toxicants during 6 months of smoking progressively reduced nicotine content cigarettes. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2012. PMID: 22354905

Okuyemi KS, Faseru B, Reed GA, Cox LS, Bronars CA, Opole I, Whembolua GL, Mayo MS, Ahluwalia JS, Benowitz NL. Effects of menthol on the pharmacokinetics of bupropion among Black smokers. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2012. PMID: 22318754

Williams JM, Gandhi KK, Lu SE, Steinberg ML, Benowitz NL. Rapid smoking may not be aversive in schizophrenia. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2012. PMID: 22318691

Cox LS, Nollen NL, Mayo MS, Choi WS, Faseru B, Benowitz NL, Tyndale RF, Okuyemi KS, Ahluwalia JS. Bupropion for smoking cessation in African American light smokers: a randomized controlled trial. Journal of the National Cancer Institute 2012. PMID: 22282543

Benowitz NL. Chronic disease management approach to treating tobacco addiction: comment on "Nicotine therapy sampling to induce quit attempts among smokers unmotivated to quit". Archives of internal medicine 2011. PMID: 22123797

Hamidovic A, Goodloe RJ, Bergen AW, Benowitz NL, Styn MA, Kasberger JL, Choquet H, Young TR, Meng Y, Palmer C, Pletcher M, Kertesz S, Hitsman B, Spring B, Jorgenson E. Gene-centric analysis of serum cotinine levels in African and European American populations. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2011. PMID: 22089314

Abrams DI, Couey P, Shade SB, Kelly ME, Benowitz NL. Cannabinoid-opioid interaction in chronic pain. Volume 90 of Issue 6. Clinical pharmacology and therapeutics 2011. PMID: 22048225

King DP, Paciga S, Pickering E, Benowitz NL, Bierut LJ, Conti DV, Kaprio J, Lerman C, Park PW. Smoking cessation pharmacogenetics: analysis of varenicline and bupropion in placebo-controlled clinical trials. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2011. PMID: 22048466

Hukkanen J, Jacob P, Peng M, Dempsey D, Benowitz NL. Effect of nicotine on cytochrome P450 1A2 activity. British journal of clinical pharmacology 2011. PMID: 21599724

Prochaska JJ, Benowitz NL, Glantz SA, Hudmon KS, Grossman W. Cardiology Rx for Change: improving clinical attention to tobacco use and secondhand smoke exposure in cardiology. Volume 34 of Issue 12. Clinical cardiology 2011. PMID: 21987417

Jacob P, Abu Raddaha AH, Dempsey D, Havel C, Peng M, Yu L, Benowitz NL. Nicotine, carbon monoxide, and carcinogen exposure after a single use of a water pipe. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2011. PMID: 21908725

Wang YG, Swick TJ, Carter LP, Thorpy MJ, Benowitz NL. Sodium oxybate: updates and correction to previously published safety data. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2011. PMID: 21897784

Benowitz NL. Smokeless tobacco as a nicotine delivery device: harm or harm reduction? Clinical pharmacology and therapeutics 2011. PMID: 21934719

Lee W, Bergen AW, Swan GE, Li D, Liu J, Thomas P, Tyndale RF, Benowitz NL, Lerman C, Conti DV. Gender-stratified gene and gene-treatment interactions in smoking cessation. The pharmacogenomics journal 2011. PMID: 21808284

Audrain-McGovern J, Benowitz NL. Cigarette smoking, nicotine, and body weight. Clinical pharmacology and therapeutics 2011. PMID: 21633341

Matt GE, Quintana PJ, Destaillats H, Gundel LA, Sleiman M, Singer BC, Jacob P, Benowitz N, Winickoff JP, Rehan V, Talbot P, Schick S, Samet J, Wang Y, Hang B, Martins-Green M, Pankow JF, Hovell MF. Thirdhand tobacco smoke: emerging evidence and arguments for a multidisciplinary research agenda. Environmental health perspectives 2011. PMID: 21628107

Williams JM, Gandhi KK, Lu SE, Kumar S, Steinberg ML, Cottler B, Benowitz NL. Shorter interpuff interval is associated with higher nicotine intake in smokers with schizophrenia. Drug and alcohol dependence 2011. PMID: 21596491

Benowitz NL, Dains KM, Dempsey D, Wilson M, Jacob P. Racial differences in the relationship between number of cigarettes smoked and nicotine and carcinogen exposure. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2011. PMID: 21546441

Benowitz NL, Samet JM. The threat of menthol cigarettes to U.S. public health. The New England journal of medicine 2011. PMID: 21542737

Pérez-Stable EJ, Benowitz NL. Do biological differences help explain tobacco-related disparities? American journal of health promotion : AJHP 2011. PMID: 21510792

Ahmed B, Jacob P, Allen F, Benowitz N. Attitudes and practices of hookah smokers in the San Francisco Bay Area. Journal of psychoactive drugs 2011. PMID: 21858960

Hamidovic A, Kasberger JL, Young TR, Goodloe RJ, Redline S, Buxbaum SG, Benowitz NL, Bergen AW, Butler KR, Franceschini N, Gharib SA, Hitsman B, Levy D, Meng Y, Papanicolaou GJ, Preis SR, Spring B, Styn MA, Tong EK, White WB, Wiggins KL, Jorgenson E. Genetic variability of smoking persistence in African Americans. Cancer prevention research (Philadelphia, Pa.) 2011. PMID: 21436384

Calfee CS, Matthay MA, Eisner MD, Benowitz N, Call M, Pittet JF, Cohen MJ. Active and passive cigarette smoking and acute lung injury after severe blunt trauma. American journal of respiratory and critical care medicine 2011. PMID: 21471091

Falcone M, Jepson C, Benowitz N, Bergen AW, Pinto A, Wileyto EP, Baldwin D, Tyndale RF, Lerman C, Ray R. Association of the nicotine metabolite ratio and CHRNA5/CHRNA3 polymorphisms with smoking rate among treatment-seeking smokers. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2011. PMID: 21385908

Cox LS, Faseru B, Mayo MS, Krebill R, Snow TS, Bronars CA, Nollen NL, Choi WS, Okuyemi KS, Salzman GA, Benowitz NL, Tyndale RF, Ahluwalia JS. Design, baseline characteristics, and retention of African American light smokers into a randomized trial involving biological data. Trials 2011. PMID: 21266057

Goniewicz ML, Eisner MD, Lazcano-Ponce E, Zielinska-Danch W, Koszowski B, Sobczak A, Havel C, Jacob P, Benowitz NL. Comparison of urine cotinine and the tobacco-specific nitrosamine metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and their ratio to discriminate active from passive smoking. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2011. PMID: 21330276

Polosa R, Benowitz NL. Treatment of nicotine addiction: present therapeutic options and pipeline developments. Trends in pharmacological sciences 2011. PMID: 21256603

Strasser AA, Benowitz NL, Pinto AG, Tang KZ, Hecht SS, Carmella SG, Tyndale RF, Lerman CE. Nicotine metabolite ratio predicts smoking topography and carcinogen biomarker level. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2011. PMID: 21212060

Hsieh SJ, Ware LB, Eisner MD, Yu L, Jacob P, Havel C, Goniewicz ML, Matthay MA, Benowitz NL, Calfee CS. Biomarkers increase detection of active smoking and secondhand smoke exposure in critically ill patients. Critical care medicine 2011. PMID: 20935560

Jacob P, Yu L, Duan M, Ramos L, Yturralde O, Benowitz NL. Determination of the nicotine metabolites cotinine and trans-3'-hydroxycotinine in biologic fluids of smokers and non-smokers using liquid chromatography-tandem mass spectrometry: biomarkers for tobacco smoke exposure and for phenotyping cytochrome P450 2 Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2010. PMID: 21208832

Zapawa LM, Hughes JR, Benowitz NL, Rigotti NA, Shiffman S. Cautions and warnings on the US OTC label for nicotine replacement: what's a doctor to do? Addictive behaviors 2010. PMID: 21220188

Frey P, Waters DD, DeMicco DA, Breazna A, Samuels L, Pipe A, Wun CC, Benowitz NL. Impact of smoking on cardiovascular events in patients with coronary disease receiving contemporary medical therapy (from the Treating to New Targets [TNT] and the Incremental Decrease in End Points Through Aggressive Lipid Lowering [IDEAL] trials). The American journal of cardiology 2010. PMID: 21129718

Benowitz NL, Dains KM, Dempsey D, Havel C, Wilson M, Jacob P. Urine menthol as a biomarker of mentholated cigarette smoking. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010. PMID: 20962297

Hatsukami DK, Perkins KA, Lesage MG, Ashley DL, Henningfield JE, Benowitz NL, Backinger CL, Zeller M. Nicotine reduction revisited: science and future directions. Tobacco control 2010. PMID: 20876072

Piano MR, Benowitz NL, Fitzgerald GA, Corbridge S, Heath J, Hahn E, Pechacek TF, Howard G. Impact of smokeless tobacco products on cardiovascular disease: implications for policy, prevention, and treatment: a policy statement from the American Heart Association. Circulation 2010. PMID: 20837898

Benowitz N, Goniewicz ML, Eisner MD, Lazcano-Ponce E, Zielinska-Danch W, Koszowski B, Sobczak A, Havel C, Jacob P. Urine cotinine underestimates exposure to the tobacco-derived lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in passive compared with active smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010. PMID: 20805316

Williams JM, Gandhi KK, Benowitz NL. Carbamazepine but not valproate induces CYP2A6 activity in smokers with mental illness. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010. PMID: 20719908

Mumenthaler MS, Benowitz NL, Taylor JL, Friedman L, Noda A, Yesavage JA. Nicotine deprivation and pilot performance during simulated flight. Aviation, space, and environmental medicine 2010. PMID: 20597245

Aquilina NJ, Delgado-Saborit JM, Meddings C, Baker S, Harrison RM, Jacob P, Wilson M, Yu L, Duan M, Benowitz NL. Environmental and biological monitoring of exposures to PAHs and ETS in the general population. Environment international 2010. PMID: 20591483

Williams JM, Gandhi KK, Lu SE, Kumar S, Shen J, Foulds J, Kipen H, Benowitz NL. Higher nicotine levels in schizophrenia compared with controls after smoking a single cigarette. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2010. PMID: 20584771

Benowitz NL. Nicotine addiction. The New England journal of medicine 2010. PMID: 20554984

Gan Q, Lu W, Xu J, Li X, Goniewicz M, Benowitz NL, Glantz SA. Chinese 'low-tar' cigarettes do not deliver lower levels of nicotine and carcinogens. Volume 19 of Issue 5. Tobacco control 2010. PMID: 20507920

Benowitz NL, Dains KM, Dempsey D, Yu L, Jacob P. Estimation of nicotine dose after low-level exposure using plasma and urine nicotine metabolites. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010. PMID: 20447913

Foianini A, Joseph Wiegand T, Benowitz N. What is the role of lidocaine or phenytoin in tricyclic antidepressant-induced cardiotoxicity? Clinical toxicology (Philadelphia, Pa.) 2010. PMID: 20507243

Lerman C, Jepson C, Wileyto EP, Patterson F, Schnoll R, Mroziewicz M, Benowitz N, Tyndale RF. Genetic variation in nicotine metabolism predicts the efficacy of extended-duration transdermal nicotine therapy. Clinical pharmacology and therapeutics 2010. PMID: 20336063

Gandhi KK, Williams JM, Menza M, Galazyn M, Benowitz NL. Higher serum caffeine in smokers with schizophrenia compared to smoking controls. Drug and alcohol dependence 2010. PMID: 20227198

Hukkanen J, Ukkola O, Benowitz NL. Varenicline and pheochromocytoma. Annals of internal medicine 2010. PMID: 20194248

Benowitz NL. Secondhand smoke and infectious disease in adults: A global women's health concern: Comment on "Passive Smoking and Tuberculosis". Archives of internal medicine 2010. PMID: 20142577

Hukkanen J, Jacob Iii P, Peng M, Dempsey D, Benowitz NL. Effects of nicotine on cytochrome P450 2A6 and 2E1 activities. British journal of clinical pharmacology 2010. PMID: 20233178

Mwenifumbo JC, Zhou Q, Benowitz NL, Sellers EM, Tyndale RF. New CYP2A6 gene deletion and conversion variants in a population of Black African descent. Pharmacogenomics 2010. PMID: 20136358

Rigotti NA, Pipe AL, Benowitz NL, Arteaga C, Garza D, Tonstad S. Efficacy and safety of varenicline for smoking cessation in patients with cardiovascular disease: a randomized trial. Circulation 2010. PMID: 20048210

Gan Q, Yang J, Yang G, Goniewicz M, Benowitz NL, Glantz SA. Chinese "herbal" cigarettes are as carcinogenic and addictive as regular cigarettes. Volume 18 of Issue 12. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009. PMID: 19959701

Goniewicz ML, Havel CM, Peng MW, Jacob P, Dempsey D, Yu L, Zielinska-Danch W, Koszowski B, Czogala J, Sobczak A, Benowitz NL. Elimination kinetics of the tobacco-specific biomarker and lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009. PMID: 19959691

Ho MK, Faseru B, Choi WS, Nollen NL, Mayo MS, Thomas JL, Okuyemi KS, Ahluwalia JS, Benowitz NL, Tyndale RF. Utility and relationships of biomarkers of smoking in African-American light smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009. PMID: 19959692

Bernert JT, Jacob P, Holiday DB, Benowitz NL, Sosnoff CS, Doig MV, Feyerabend C, Aldous KM, Sharifi M, Kellogg MD, Langman LJ. Interlaboratory comparability of serum cotinine measurements at smoker and nonsmoker concentration levels: a round-robin study. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2009. PMID: 19933777

Hovell MF, Zakarian JM, Matt GE, Liles S, Jones JA, Hofstetter CR, Larson SN, Benowitz NL. Counseling to reduce children's secondhand smoke exposure and help parents quit smoking: a controlled trial. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2009. PMID: 19875762

Lessov-Schlaggar CN, Benowitz NL, Jacob P, Swan GE. Genetic influences on individual differences in nicotine glucuronidation. Twin research and human genetics : the official journal of the International Society for Twin Studies 2009. PMID: 19803778

Benowitz NL, Schultz KE, Haller CA, Wu AH, Dains KM, Jacob P. Prevalence of smoking assessed biochemically in an urban public hospital: a rationale for routine cotinine screening. American journal of epidemiology 2009. PMID: 19713287

Wang YG, Swick TJ, Carter LP, Thorpy MJ, Benowitz NL. Safety overview of postmarketing and clinical experience of sodium oxybate (Xyrem): abuse, misuse, dependence, and diversion. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2009. PMID: 19968016

Eisner MD, Jacob P, Benowitz NL, Balmes J, Blanc PD. Longer term exposure to secondhand smoke and health outcomes in COPD: impact of urine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol. Volume 11 of Issue 8. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2009. PMID: 19587064

Thomas PD, Mi H, Swan GE, Lerman C, Benowitz N, Tyndale RF, Bergen AW, Conti DV. A systems biology network model for genetic association studies of nicotine addiction and treatment. Pharmacogenetics and genomics 2009. PMID: 19525886

Benowitz NL, Dains KM, Dempsey D, Herrera B, Yu L, Jacob P. Urine nicotine metabolite concentrations in relation to plasma cotinine during low-level nicotine exposure. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2009. PMID: 19525206

He Y, Bergen AW, Hops H, Andrews JA, Tildesley E, Lessov-Schlaggar CN, Webster C, Benowitz N, Swan GE. Genome-wide linkage of cotinine pharmacokinetics suggests candidate regions on chromosomes 9 and 11. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009. PMID: 18785207

Dukic VM, Niessner M, Pickett KE, Benowitz NL, Wakschlag LS. Calibrating self-reported measures of maternal smoking in pregnancy via bioassays using a Monte Carlo approach. International journal of environmental research and public health 2009. PMID: 19578458

Bergen AW, Conti DV, Van Den Berg D, Lee W, Liu J, Li D, Guo N, Mi H, Thomas PD, Lessov-Schlaggar CN, Krasnow R, He Y, Nishita D, Jiang R, McClure JB, Tildesley E, Hops H, Tyndale RF, Benowitz NL, Lerman C, Swan GE. Dopamine genes and nicotine dependence in treatment-seeking and community smokers. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009. PMID: 19494806

Swan GE, Lessov-Schlaggar CN, Bergen AW, He Y, Tyndale RF, Benowitz NL. Genetic and environmental influences on the ratio of 3'hydroxycotinine to cotinine in plasma and urine. Pharmacogenetics and genomics 2009. PMID: 19300303

Bondy SJ, Zhang B, Kreiger N, Selby P, Benowitz N, Travis H, Florescu A, Greenspan NR, Ferrence R. Impact of an indoor smoking ban on bar workers' exposure to secondhand smoke. Journal of occupational and environmental medicine 2009. PMID: 19369895

Ho MK, Mwenifumbo JC, Al Koudsi N, Okuyemi KS, Ahluwalia JS, Benowitz NL, Tyndale RF. Association of nicotine metabolite ratio and CYP2A6 genotype with smoking cessation treatment in African-American light smokers. Clinical pharmacology and therapeutics 2009. PMID: 19279561

Benowitz NL, Dains KM, Hall SM, Stewart S, Wilson M, Dempsey D, Jacob P. Progressive commercial cigarette yield reduction: biochemical exposure and behavioral assessment. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009. PMID: 19258480

Rubinstein ML, Benowitz NL, Auerback GM, Moscicki AB. Withdrawal in adolescent light smokers following 24-hour abstinence. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2009. PMID: 19246428

Benowitz NL, Hukkanen J, Jacob P. Nicotine chemistry, metabolism, kinetics and biomarkers. Handbook of experimental pharmacology 2009. PMID: 19184645

Benowitz NL. Pharmacology of nicotine: addiction, smoking-induced disease, and therapeutics. Annual review of pharmacology and toxicology 2009. PMID: 18834313

Benowitz NL, Bernert JT, Caraballo RS, Holiday DB, Wang J. Optimal serum cotinine levels for distinguishing cigarette smokers and nonsmokers within different racial/ethnic groups in the United States between 1999 and 2004. American journal of epidemiology 2008. PMID: 19019851

Schnoll RA, Patterson F, Wileyto EP, Tyndale RF, Benowitz N, Lerman C. Nicotine metabolic rate predicts successful smoking cessation with transdermal nicotine: a validation study. Pharmacology, biochemistry, and behavior 2008. PMID: 19000709

Jacob P, Havel C, Lee DH, Yu L, Eisner MD, Benowitz NL. Subpicogram per milliliter determination of the tobacco-specific carcinogen metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in human urine using liquid chromatography-tandem mass spectrometry. Analytical chemistry 2008. PMID: 18841944

Rubinstein ML, Benowitz NL, Auerback GM, Moscicki AB. A randomized trial of nicotine nasal spray in adolescent smokers. Pediatrics 2008. PMID: 18762494

Perkins KA, Lerman C, Grottenthaler A, Ciccocioppo MM, Milanak M, Conklin CA, Bergen AW, Benowitz NL. Dopamine and opioid gene variants are associated with increased smoking reward and reinforcement owing to negative mood. Behavioural pharmacology 2008. PMID: 18690118

Perkins KA, Lerman C, Coddington S, Jetton C, Karelitz JL, Wilson A, Jennings JR, Ferrell R, Bergen AW, Benowitz NL. Gene and gene by sex associations with initial sensitivity to nicotine in nonsmokers. Behavioural pharmacology 2008. PMID: 18690117

Benowitz NL. Nicotine and postoperative management of pain. Anesthesia and analgesia 2008. PMID: 18713874

Rubinstein ML, Benowitz NL, Auerback GM, Moscicki AB. Rate of nicotine metabolism and withdrawal symptoms in adolescent light smokers. Pediatrics 2008. PMID: 18762498

Sohn M, Benowitz N, Stotts N, Christopherson D, Kim KS, Jang YS, Ahn MS, Froelicher ES. Smoking behavior in men hospitalized with cardiovascular disease in Korea: a cross-sectional descriptive study. Heart & lung : the journal of critical care 2008. PMID: 18790337

Tutka P, Dempsey DA, Jacob P, Benowitz NL, Kroetz DL. Nicotine metabolism in pregnant and nonpregnant rabbits. Volume 10 of Issue 8. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2008. PMID: 18686186

Xing J, Chen M, Wood CG, Lin J, Spitz MR, Ma J, Amos CI, Shields PG, Benowitz NL, Gu J, de Andrade M, Swan GE, Wu X. Mitochondrial DNA content: its genetic heritability and association with renal cell carcinoma. Journal of the National Cancer Institute 2008. PMID: 18664653

Conti DV, Lee W, Li D, Liu J, Van Den Berg D, Thomas PD, Bergen AW, Swan GE, Tyndale RF, Benowitz NL, Lerman C. Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation. Human molecular genetics 2008. PMID: 18593715

Weiss ST, McLeod HL, Flockhart DA, Dolan ME, Benowitz NL, Johnson JA, Ratain MJ, Giacomini KM. Creating and evaluating genetic tests predictive of drug response. Volume 7 of Issue 7. Nature reviews. Drug discovery 2008. PMID: 18587383

Piper ME, McCarthy DE, Bolt DM, Smith SS, Lerman C, Benowitz N, Fiore MC, Baker TB. Assessing dimensions of nicotine dependence: an evaluation of the Nicotine Dependence Syndrome Scale (NDSS) and the Wisconsin Inventory of Smoking Dependence Motives (WISDM). Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2008. PMID: 18584464

Haller C, Kearney T, Bent S, Ko R, Benowitz N, Olson K. Dietary supplement adverse events: report of a one-year poison center surveillance project. Journal of medical toxicology : official journal of the American College of Medical Toxicology 2008. PMID: 18570167

Triche EW, Grosso LM, Belanger K, Darefsky AS, Benowitz NL, Bracken MB. Chocolate consumption in pregnancy and reduced likelihood of preeclampsia. Epidemiology (Cambridge, Mass.) 2008. PMID: 18379424

Benowitz NL, Lessov-Schlaggar CN, Swan GE. Genetic influences in the variation in renal clearance of nicotine and cotinine. Clinical pharmacology and therapeutics 2008. PMID: 18388871

Patterson F, Schnoll RA, Wileyto EP, Pinto A, Epstein LH, Shields PG, Hawk LW, Tyndale RF, Benowitz N, Lerman C. Toward personalized therapy for smoking cessation: a randomized placebo-controlled trial of bupropion. Clinical pharmacology and therapeutics 2008. PMID: 18388868

Benowitz NL. Neurobiology of nicotine addiction: implications for smoking cessation treatment. The American journal of medicine 2008. PMID: 18342164

Haller CA, Duan M, Jacob P, Benowitz N. Human pharmacology of a performance-enhancing dietary supplement under resting and exercise conditions. British journal of clinical pharmacology 2008. PMID: 18341680

Grosso LM, Triche E, Benowitz NL, Bracken MB. Prenatal caffeine assessment: fetal and maternal biomarkers or self-reported intake? Annals of epidemiology 2008. PMID: 18083538

Benowitz NL. Clinical pharmacology of nicotine: implications for understanding, preventing, and treating tobacco addiction. Clinical pharmacology and therapeutics 2008. PMID: 18305452

Figueiredo VC, Szklo M, Szklo AS, Benowitz N, Lozana JA, Casado L, Masson E, Samet J. Determinants of salivary cotinine level: a population-based study in Brazil. Revista de saude publica 2007. PMID: 17992352

Ring HZ, Valdes AM, Nishita DM, Prasad S, Jacob P, Tyndale RF, Swan GE, Benowitz NL. Gene-gene interactions between CYP2B6 and CYP2A6 in nicotine metabolism. Pharmacogenetics and genomics 2007. PMID: 18004205

Benowitz NL, Hall SM, Stewart S, Wilson M, Dempsey D, Jacob P. Nicotine and carcinogen exposure with smoking of progressively reduced nicotine content cigarette. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007. PMID: 18006940

Lin J, Swan GE, Shields PG, Benowitz NL, Gu J, Amos CI, de Andrade M, Spitz MR, Wu X. Mutagen sensitivity and genetic variants in nucleotide excision repair pathway: genotype-phenotype correlation. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007. PMID: 17932354

Lazcano-Ponce E, Benowitz N, Sanchez-Zamorano LM, Barbosa-Sanchez L, Valdes-Salgado R, Jacob P, Diaz R, Hernandez-Avila M. Secondhand smoke exposure in Mexican discotheques. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2007. PMID: 17852765

Etter JF, Lukas RJ, Benowitz NL, West R, Dresler CM. Cytisine for smoking cessation: a research agenda. Drug and alcohol dependence 2007. PMID: 17825502

Sohn M, Stotts NA, Benowitz N, Christopherson D, Kim KS, Jang YS, Ahn MS, Froelicher ES. Beliefs about health, smoking, and future smoking cessation among South Korean men hospitalized for cardiovascular disease. Heart & lung : the journal of critical care 2007. PMID: 17845880

Hutchison KE, Allen DL, Filbey FM, Jepson C, Lerman C, Benowitz NL, Stitzel J, Bryan A, McGeary J, Haughey HM. CHRNA4 and tobacco dependence: from gene regulation to treatment outcome. Archives of general psychiatry 2007. PMID: 17768273

Lerman C, LeSage MG, Perkins KA, O'Malley SS, Siegel SJ, Benowitz NL, Corrigall WA. Translational research in medication development for nicotine dependence. Nature reviews. Drug discovery 2007. PMID: 17690709

Williams JM, Gandhi KK, Steinberg ML, Foulds J, Ziedonis DM, Benowitz NL. Higher nicotine and carbon monoxide levels in menthol cigarette smokers with and without schizophrenia. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2007. PMID: 17654300

Stepanov I, Hecht SS, Lindgren B, Jacob P, Wilson M, Benowitz NL. Relationship of human toenail nicotine, cotinine, and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol to levels of these biomarkers in plasma and urine. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007. PMID: 17627002

Benowitz NL. Cigarette smoking and the personalization of irinotecan therapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007. PMID: 17563392

Lee AM, Jepson C, Shields PG, Benowitz N, Lerman C, Tyndale RF. CYP2B6 genotype does not alter nicotine metabolism, plasma levels, or abstinence with nicotine replacement therapy. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007. PMID: 17548706

Swan GE, Lessov-Schlaggar CN, Krasnow RE, Wilhelmsen KC, Jacob P, Benowitz NL. Genetic and environmental sources of variation in heart rate response to infused nicotine in twins. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007. PMID: 17548663

Mwenifumbo JC, Lessov-Schlaggar CN, Zhou Q, Krasnow RE, Swan GE, Benowitz NL, Tyndale RF. Identification of novel CYP2A6*1B variants: the CYP2A6*1B allele is associated with faster in vivo nicotine metabolism. Clinical pharmacology and therapeutics 2007. PMID: 17522595

Altman RB, Benowitz N, Gurwitz D, Lunshof J, Relling M, Lamba J, Wieben E, Mooney S, Giacomini K, Weiss S, Johnson JA, McLeod H, Flockhart D, Weinshilboum R, Shuldiner AR, Roden D, Krauss RM, Ratain M. Genetic nondiscrimination legislation: a critical prerequisite for pharmacogenomics data sharing. Volume 8 of Issue 5. Pharmacogenomics 2007. PMID: 17465717

Abrams DI, Vizoso HP, Shade SB, Jay C, Kelly ME, Benowitz NL. Vaporization as a smokeless cannabis delivery system: a pilot study. Volume 82 of Issue 5. Clinical pharmacology and therapeutics 2007. PMID: 17429350

Dukic VM, Niessner M, Benowitz N, Hans S, Wakschlag L. Modeling the relationship of cotinine and self-reported measures of maternal smoking during pregnancy: a deterministic approach. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2007. PMID: 17454700

Giacomini KM, Brett CM, Altman RB, Benowitz NL, Dolan ME, Flockhart DA, Johnson JA, Hayes DF, Klein T, Krauss RM, Kroetz DL, McLeod HL, Nguyen AT, Ratain MJ, Relling MV, Reus V, Roden DM, Schaefer CA, Shuldiner AR, Skaar T, Tantisira K, Tyndale RF, Wang L, Weinshilboum RM, Weiss ST, Zineh I. The pharmacogenetics research network: from SNP discovery to clinical drug response. Volume 81 of Issue 3. Clinical pharmacology and therapeutics 2007. PMID: 17339863

Kandel DB, Hu MC, Schaffran C, Udry JR, Benowitz NL. Urine nicotine metabolites and smoking behavior in a multiracial/multiethnic national sample of young adults. American journal of epidemiology 2007. PMID: 17322544

Jacob P, Wilson M, Benowitz NL. Determination of phenolic metabolites of polycyclic aromatic hydrocarbons in human urine as their pentafluorobenzyl ether derivatives using liquid chromatography-tandem mass spectrometry. Analytical chemistry 2007. PMID: 17222024

Levi M, Dempsey DA, Benowitz NL, Sheiner LB. Population pharmacokinetics of nicotine and its metabolites I. Model development. Journal of pharmacokinetics and pharmacodynamics 2007. PMID: 17206524

Levi M, Dempsey DA, Benowitz NL, Sheiner LB. Prediction methods for nicotine clearance using cotinine and 3-hydroxy-cotinine spot saliva samples II. Model application. Journal of pharmacokinetics and pharmacodynamics 2007. PMID: 17206525

Rubinstein ML, Thompson PJ, Benowitz NL, Shiffman S, Moscicki AB. Cotinine levels in relation to smoking behavior and addiction in young adolescent smokers. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2007. PMID: 17365743

Mabry PL, Tooze JA, Moser RP, Augustson EM, Malcolm RJ, Benowitz NL. Nicotine, cotinine, withdrawal, and craving patterns during smoking and nicotine nasal spray use: results from a pilot study with African American men. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2007. PMID: 17365738

Matt GE, Hovell MF, Quintana PJ, Zakarian J, Liles S, Meltzer SB, Benowitz NL. The variability of urinary cotinine levels in young children: implications for measuring ETS exposure. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2007. PMID: 17365739

Benowitz NL, Jacob P, Herrera B. Nicotine intake and dose response when smoking reduced-nicotine content cigarettes. Clinical pharmacology and therapeutics 2006. PMID: 17178270

Roden DM, Altman RB, Benowitz NL, Flockhart DA, Giacomini KM, Johnson JA, Krauss RM, McLeod HL, Ratain MJ, Relling MV, Ring HZ, Shuldiner AR, Weinshilboum RM, Weiss ST. Pharmacogenomics: challenges and opportunities. Volume 145 of Issue 10. Annals of internal medicine 2006. PMID: 17116919

Benowitz NL, Swan GE, Jacob P, Lessov-Schlaggar CN, Tyndale RF. CYP2A6 genotype and the metabolism and disposition kinetics of nicotine. Clinical pharmacology and therapeutics 2006. PMID: 17112802

Hukkanen J, Jacob P, Benowitz NL. Effect of grapefruit juice on cytochrome P450 2A6 and nicotine renal clearance. Clinical pharmacology and therapeutics 2006. PMID: 17112808

Matt GE, Quintana PJ, Liles S, Hovell MF, Zakarian JM, Jacob P, Benowitz NL. Evaluation of urinary trans-3'-hydroxycotinine as a biomarker of children's environmental tobacco smoke exposure. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2006. PMID: 17056471

Blackford AL, Yang G, Hernandez-Avila M, Przewozniak K, Zatonski W, Figueiredo V, Avila-Tang E, Ma J, Benowitz NL, Samet JM. Cotinine concentration in smokers from different countries: relationship with amount smoked and cigarette type. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006. PMID: 17021350

Johnstone E, Benowitz N, Cargill A, Jacob R, Hinks L, Day I, Murphy M, Walton R. Determinants of the rate of nicotine metabolism and effects on smoking behavior. Clinical pharmacology and therapeutics 2006. PMID: 17015050

Repace J, Hughes E, Benowitz N. Exposure to second-hand smoke air pollution assessed from bar patrons' urinary cotinine. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2006. PMID: 17008197

Thai D, Dyer JE, Benowitz NL, Haller CA. Gamma-hydroxybutyrate and ethanol effects and interactions in humans. Journal of clinical psychopharmacology 2006. PMID: 16974199

Pletcher MJ, Hulley BJ, Houston T, Kiefe CI, Benowitz N, Sidney S. Menthol cigarettes, smoking cessation, atherosclerosis, and pulmonary function: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Archives of internal medicine 2006. PMID: 17000950

Murphy NG, Albin C, Tai W, Benowitz NL. Anabasine toxicity from a topical folk remedy. Clinical pediatrics 2006. PMID: 16928847

Matta SG, Balfour DJ, Benowitz NL, Boyd RT, Buccafusco JJ, Caggiula AR, Craig CR, Collins AC, Damaj MI, Donny EC, Gardiner PS, Grady SR, Heberlein U, Leonard SS, Levin ED, Lukas RJ, Markou A, Marks MJ, McCallum SE, Parameswaran N, Perkins KA, Picciotto MR, Quik M, Rose JE, Rothenfluh A, Schafer WR, Stolerman IP, Tyndale RF, Wehner JM, Zirger JM. Guidelines on nicotine dose selection for in vivo research. Psychopharmacology 2006. PMID: 16896961

Hatsukami DK, Benowitz NL, Rennard SI, Oncken C, Hecht SS. Biomarkers to assess the utility of potential reduced exposure tobacco products. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2006. PMID: 16920658

Kandel DB, Schaffran C, Griesler PC, Hu MC, Davies M, Benowitz N. Salivary cotinine concentration versus self-reported cigarette smoking: Three patterns of inconsistency in adolescence. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2006. PMID: 16920650

Block G, Dietrich M, Norkus E, Jensen C, Benowitz NL, Morrow JD, Hudes M, Packer L. Intraindividual variability of plasma antioxidants, markers of oxidative stress, C-reactive protein, cotinine, and other biomarkers. Epidemiology (Cambridge, Mass.) 2006. PMID: 16755268

Lea RA, Dickson S, Benowitz NL. Within-subject variation of the salivary 3HC/COT ratio in regular daily smokers: prospects for estimating CYP2A6 enzyme activity in large-scale surveys of nicotine metabolic rate. Journal of analytical toxicology 2006. PMID: 16872570

Wu X, Spitz MR, Amos CI, Lin J, Shao L, Gu J, de Andrade M, Benowitz NL, Shields PG, Swan GE. Mutagen sensitivity has high heritability: evidence from a twin study. Cancer research 2006. PMID: 16778168

Eisner MD, Balmes J, Yelin EH, Katz PP, Hammond SK, Benowitz N, Blanc PD. Directly measured secondhand smoke exposure and COPD health outcomes. Volume 6. BMC pulmonary medicine 2006. PMID: 16756671

Swan GE, Hops H, Wilhelmsen KC, Lessov-Schlaggar CN, Cheng LS, Hudmon KS, Amos CI, Feiler HS, Ring HZ, Andrews JA, Tildesley E, Benowitz N. A genome-wide screen for nicotine dependence susceptibility loci. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2006. PMID: 16671072

Lerman C, Tyndale R, Patterson F, Wileyto EP, Shields PG, Pinto A, Benowitz N. Nicotine metabolite ratio predicts efficacy of transdermal nicotine for smoking cessation. Clinical pharmacology and therapeutics 2006. PMID: 16765148

Benowitz NL, Lessov-Schlaggar CN, Swan GE, Jacob P. Female sex and oral contraceptive use accelerate nicotine metabolism. Clinical pharmacology and therapeutics 2006. PMID: 16678549

Le Houezec J, Benowitz NL. Smoking habits, nicotine use, and congenital malformations. Obstetrics and gynecology 2006. PMID: 16648425

Al Koudsi N, Mwenifumbo JC, Sellers EM, Benowitz NL, Swan GE, Tyndale RF. Characterization of the novel CYP2A6*21 allele using in vivo nicotine kinetics. European journal of clinical pharmacology 2006. PMID: 16758265

Grosso LM, Triche EW, Belanger K, Benowitz NL, Holford TR, Bracken MB. Caffeine metabolites in umbilical cord blood, cytochrome P-450 1A2 activity, and intrauterine growth restriction. American journal of epidemiology 2006. PMID: 16641310

Hatsukami DK, Benowitz NL, Rennard SI, Oncken C, Hecht SS. Biomarkers to assess the utility of potential reduced exposure tobacco products. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2006. PMID: 16766411

Malaiyandi V, Lerman C, Benowitz NL, Jepson C, Patterson F, Tyndale RF. Impact of CYP2A6 genotype on pretreatment smoking behaviour and nicotine levels from and usage of nicotine replacement therapy. Molecular psychiatry 2006. PMID: 16402128

Lea R, Benowitz N, Green M, Fowles J, Vishvanath A, Dickson S, Lea M, Woodward A, Chambers G, Phillips D. Ethnic differences in nicotine metabolic rate among New Zealanders. The New Zealand medical journal 2005. PMID: 16372023

Wilhelmsen KC, Swan GE, Cheng LS, Lessov-Schlaggar CN, Amos CI, Feiler HS, Hudmon KS, Ring HZ, Andrews JA, Tildesley E, Benowitz NL, Hops H. Support for previously identified alcoholism susceptibility Loci in a cohort selected for smoking behavior. Alcoholism, clinical and experimental research 2005. PMID: 16385180

Haller CA, Benowitz NL, Jacob P. Hemodynamic effects of ephedra-free weight-loss supplements in humans. The American journal of medicine 2005. PMID: 16164886

Hukkanen J, Dempsey D, Jacob P, Benowitz NL. Effect of pregnancy on a measure of FMO3 activity. British journal of clinical pharmacology 2005. PMID: 16042678

Williams JM, Ziedonis DM, Abanyie F, Steinberg ML, Foulds J, Benowitz NL. Increased nicotine and cotinine levels in smokers with schizophrenia and schizoaffective disorder is not a metabolic effect. Schizophrenia research 2005. PMID: 15961287

Benowitz NL, Jacob P, Bernert JT, Wilson M, Wang L, Allen F, Dempsey D. Carcinogen exposure during short-term switching from regular to "light" cigarettes. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005. PMID: 15941944

Haller CA, Jacob P, Benowitz NL. Short-term metabolic and hemodynamic effects of ephedra and guarana combinations. Clinical pharmacology and therapeutics 2005. PMID: 15961987

Gray N, Henningfield JE, Benowitz NL, Connolly GN, Dresler C, Fagerstrom K, Jarvis MJ, Boyle P. Toward a comprehensive long term nicotine policy. Tobacco control 2005. PMID: 15923465

Hukkanen J, Gourlay SG, Kenkare S, Benowitz NL. Influence of menstrual cycle on cytochrome P450 2A6 activity and cardiovascular effects of nicotine. Clinical pharmacology and therapeutics 2005. PMID: 15735610

Csajka C, Haller CA, Benowitz NL, Verotta D. Mechanistic pharmacokinetic modelling of ephedrine, norephedrine and caffeine in healthy subjects. British journal of clinical pharmacology 2005. PMID: 15752380

Hukkanen J, Jacob P, Benowitz NL. Metabolism and disposition kinetics of nicotine. Pharmacological reviews 2005. PMID: 15734728

Swan GE, Benowitz NL, Lessov CN, Jacob P, Tyndale RF, Wilhelmsen K. Nicotine metabolism: the impact of CYP2A6 on estimates of additive genetic influence. Pharmacogenetics and genomics 2005. PMID: 15861035

Vukovich MD, Schoorman R, Heilman C, Jacob P, Benowitz NL. Caffeine-herbal ephedra combination increases resting energy expenditure, heart rate and blood pressure. Clinical and experimental pharmacology & physiology 2005. PMID: 15730434

Gelal A, Balkan D, Ozzeybek D, Kaplan YC, Gurler S, Guven H, Benowitz NL. Effect of menthol on the pharmacokinetics and pharmacodynamics of felodipine in healthy subjects. European journal of clinical pharmacology 2004. PMID: 15592925

Campuzano JC, Hernandez-Avila M, Jaakkola MS, Lazcano Ponce E, Kuri Morales P, Bautista P, Benowitz NL, Ceraso M, Blackford A, Samet JM. Determinants of salivary cotinine levels among current smokers in Mexico. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2004. PMID: 15801572

Arcavi L, Benowitz NL. Cigarette smoking and infection. Archives of internal medicine 2004. PMID: 15534156

Hughes JR, Benowitz N, Hatsukami D, Mermelstein RJ, Shiffman S. Clarification of SRNT workgroup guidelines for measures in clinical trials of smoking cessation therapies. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2004. PMID: 15700922

Swan GE, Benowitz NL, Jacob P, Lessov CN, Tyndale RF, Wilhelmsen K, Krasnow RE, McElroy MR, Moore SE, Wambach M. Pharmacogenetics of nicotine metabolism in twins: methods and procedures. Twin research : the official journal of the International Society for Twin Studies 2004. PMID: 15527659

Dempsey D, Tutka P, Jacob P, Allen F, Schoedel K, Tyndale RF, Benowitz NL. Nicotine metabolite ratio as an index of cytochrome P450 2A6 metabolic activity. Clinical pharmacology and therapeutics 2004. PMID: 15229465

Henningfield JE, Benowitz NL, Connolly GN, Davis RM, Gray N, Myers ML, Zeller M. Reducing tobacco addiction through tobacco product regulation. Tobacco control 2004. PMID: 15175528

Benowitz NL, Herrera B, Jacob P. Mentholated cigarette smoking inhibits nicotine metabolism. The Journal of pharmacology and experimental therapeutics 2004. PMID: 15084646

Haller CA, Duan M, Benowitz NL, Jacob P. Concentrations of ephedra alkaloids and caffeine in commercial dietary supplements. Journal of analytical toxicology 2004. PMID: 15107143

Jacob P, Haller CA, Duan M, Yu L, Peng M, Benowitz NL. Determination of ephedra alkaloid and caffeine concentrations in dietary supplements and biological fluids. Journal of analytical toxicology 2004. PMID: 15107144

Haller CA, Jacob P, Benowitz NL. Enhanced stimulant and metabolic effects of combined ephedrine and caffeine. Clinical pharmacology and therapeutics 2004. PMID: 15060505

Benowitz N, Dempsey D. Pharmacotherapy for smoking cessation during pregnancy. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2004. PMID: 15203821

Lerman C, Kaufmann V, Rukstalis M, Patterson F, Perkins K, Audrain-McGovern J, Benowitz N. Individualizing nicotine replacement therapy for the treatment of tobacco dependence: a randomized trial. Annals of internal medicine 2004. PMID: 15023708

Haas JS, Kaplan CP, Barenboim D, Jacob P, Benowitz NL. Bupropion in breast milk: an exposure assessment for potential treatment to prevent post-partum tobacco use. Volume 13 of Issue 1. Tobacco control 2004. PMID: 14985597

Sivarajan Froelicher ES, Miller NH, Christopherson DJ, Martin K, Parker KM, Amonetti M, Lin Z, Sohn M, Benowitz N, Taylor CB, Bacchetti P. High rates of sustained smoking cessation in women hospitalized with cardiovascular disease: the Women's Initiative for Nonsmoking (WINS). Circulation 2004. PMID: 14769679

Benowitz NL. Smoking less as a treatment goal for those who cannot stop smoking. The American journal of medicine 2004. PMID: 14749168

Miao FJ, Green PG, Benowitz N, Levine JD. Central terminals of nociceptors are targets for nicotine suppression of inflammation. Neuroscience 2004. PMID: 14706790

Gourlay SG, Stead LF, Benowitz NL. Clonidine for smoking cessation. The Cochrane database of systematic reviews 2004. PMID: 15266422

Lerman C, Wileyto EP, Patterson F, Rukstalis M, Audrain-McGovern J, Restine S, Shields PG, Kaufmann V, Redden D, Benowitz N, Berrettini WH. The functional mu opioid receptor (OPRM1) Asn40Asp variant predicts short-term response to nicotine replacement therapy in a clinical trial. The pharmacogenomics journal 2004. PMID: 15007373

Benowitz NL, Peng M, Jacob P. Effects of cigarette smoking and carbon monoxide on chlorzoxazone and caffeine metabolism. Clinical pharmacology and therapeutics 2003. PMID: 14586387

Sohn M, Hartley C, Froelicher ES, Benowitz NL. Tobacco use and dependence. Seminars in oncology nursing 2003. PMID: 14702859

Swan GE, Hudmon KS, Jack LM, Hemberger K, Carmelli D, Khroyan TV, Ring HZ, Hops H, Andrews JA, Tildesley E, McBride D, Benowitz N, Webster C, Wilhelmsen KC, Feiler HS, Koenig B, Caron L, Illes J, Cheng LS. Environmental and genetic determinants of tobacco use: methodology for a multidisciplinary, longitudinal family-based investigation. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2003. PMID: 14578134

Benowitz NL, Pomerleau OF, Pomerleau CS, Jacob P. Nicotine metabolite ratio as a predictor of cigarette consumption. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2003. PMID: 14577978

Miao FJ, Green P, Benowitz N, Levine JD. Vagal modulation of spinal nicotine-induced inhibition of the inflammatory response mediated by descending antinociceptive controls. Volume 45 of Issue 5. Neuropharmacology 2003. PMID: 12941374

Abrams DI, Hilton JF, Leiser RJ, Shade SB, Elbeik TA, Aweeka FT, Benowitz NL, Bredt BM, Kosel B, Aberg JA, Deeks SG, Mitchell TF, Mulligan K, Bacchetti P, McCune JM, Schambelan M. Short-term effects of cannabinoids in patients with HIV-1 infection: a randomized, placebo-controlled clinical trial. Volume 139 of Issue 4. Annals of internal medicine 2003. PMID: 12965981

Gelal A, Guven H, Balkan D, Artok L, Benowitz NL. Influence of menthol on caffeine disposition and pharmacodynamics in healthy female volunteers. European journal of clinical pharmacology 2003. PMID: 12915954

Benowitz NL. Cigarette smoking and cardiovascular disease: pathophysiology and implications for treatment. Progress in cardiovascular diseases 2003. PMID: 12920702

Patterson F, Benowitz N, Shields P, Kaufmann V, Jepson C, Wileyto P, Kucharski S, Lerman C. Individual differences in nicotine intake per cigarette. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2003. PMID: 12750245

Jaakkola MS, Ma J, Yang G, Chin MF, Benowitz NL, Ceraso M, Samet JM. Determinants of salivary cotinine concentrations in Chinese male smokers. Preventive medicine 2003. PMID: 12634019

Winston L, Benowitz N. Once-daily dosing of aminoglycosides: how much monitoring is truly required? The American journal of medicine 2003. PMID: 12637142

Benowitz NL. Basic cardiovascular research and its implications for the medicinal use of nicotine. Journal of the American College of Cardiology 2003. PMID: 12575982

Henningfield JE, Benowitz NL, Ahijevych K, Garrett BE, Connolly GN, Wayne GF. Does menthol enhance the addictiveness of cigarettes? An agenda for research. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2003. PMID: 12745502

Dietrich M, Block G, Benowitz NL, Morrow JD, Hudes M, Jacob P, Norkus EP, Packer L. Vitamin C supplementation decreases oxidative stress biomarker f2-isoprostanes in plasma of nonsmokers exposed to environmental tobacco smoke. Nutrition and cancer 2003. PMID: 12881011

Jacob P, Hatsukami D, Severson H, Hall S, Yu L, Benowitz NL. Anabasine and anatabine as biomarkers for tobacco use during nicotine replacement therapy. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2002. PMID: 12496059

Mahrer-Imhof R, Froelicher ES, Li WW, Parker KM, Benowitz N. Women's Initiative for Nonsmoking (WINS V): under-use of nicotine replacement therapy. Heart & lung : the journal of critical care 2002. PMID: 12487015

Pitsiu M, Gries JM, Benowitz N, Gourlay SG, Verotta D. Modeling nicotine arterial-venous differences to predict arterial concentrations and input based on venous measurements: application to smokeless tobacco and nicotine gum. Journal of pharmacokinetics and pharmacodynamics 2002. PMID: 12518710

Benowitz NL. Smoking cessation trials targeted to racial and economic minority groups. JAMA 2002. PMID: 12132983

Benowitz NL, Hansson A, Jacob P. Cardiovascular effects of nasal and transdermal nicotine and cigarette smoking. Hypertension (Dallas, Tex. : 1979) 2002. PMID: 12052850

Wakschlag LS, Pickett KE, Cook E, Benowitz NL, Leventhal BL. Maternal smoking during pregnancy and severe antisocial behavior in offspring: a review. American journal of public health 2002. PMID: 12036791

Haller CA, Jacob P, Benowitz NL. Pharmacology of ephedra alkaloids and caffeine after single-dose dietary supplement use. Clinical pharmacology and therapeutics 2002. PMID: 12087345

Dempsey D, Jacob P, Benowitz NL. Accelerated metabolism of nicotine and cotinine in pregnant smokers. The Journal of pharmacology and experimental therapeutics 2002. PMID: 11961061

Campbell BJ, Rowbotham M, Davies PS, Jacob P, Benowitz NL. Systemic absorption of topical lidocaine in normal volunteers, patients with post-herpetic neuralgia, and patients with acute herpes zoster. Journal of pharmaceutical sciences 2002. PMID: 11977110

Hsue PY, Salinas CL, Bolger AF, Benowitz NL, Waters DD. Acute aortic dissection related to crack cocaine. Circulation 2002. PMID: 11927528

Kosel BW, Aweeka FT, Benowitz NL, Shade SB, Hilton JF, Lizak PS, Abrams DI. The effects of cannabinoids on the pharmacokinetics of indinavir and nelfinavir. Volume 16 of Issue 4. AIDS (London, England) 2002. PMID: 11872997

Schaedeli F, Pitsiu M, Benowitz NL, Gourlay SG, Verotta D. Influence of arterial vs. venous sampling site on nicotine tolerance model selection and parameter estimation. Journal of pharmacokinetics and pharmacodynamics 2002. PMID: 12194535

Benowitz NL, Pérez-Stable EJ, Herrera B, Jacob P. Slower metabolism and reduced intake of nicotine from cigarette smoking in Chinese-Americans. Journal of the National Cancer Institute 2002. PMID: 11792749

Hatsukami DK, Slade J, Benowitz NL, Giovino GA, Gritz ER, Leischow S, Warner KE. Reducing tobacco harm: research challenges and issues. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2002. PMID: 12573171

Benowitz NL, Griffin C, Tyndale R. Deficient C-oxidation of nicotine continued. Clinical pharmacology and therapeutics 2001. PMID: 11753274

Zevin S, Saunders S, Gourlay SG, Jacob P, Benowitz NL. Cardiovascular effects of carbon monoxide and cigarette smoking. Journal of the American College of Cardiology 2001. PMID: 11704374

Sekhon HS, Keller JA, Benowitz NL, Spindel ER. Prenatal nicotine exposure alters pulmonary function in newborn rhesus monkeys. American journal of respiratory and critical care medicine 2001. PMID: 11587984

Mannino DM, Caraballo R, Benowitz N, Repace J. Predictors of cotinine levels in US children: data from the Third National Health and Nutrition Examination Survey. Chest 2001. PMID: 11555498

Benowitz NL. Safety of nicotine in smokers with hypertension. American journal of hypertension 2001. PMID: 11465662

Miao FJ, Benowitz NL, Levine JD. Endogenous opioids suppress activation of nociceptors by sub-nanomolar nicotine. British journal of pharmacology 2001. PMID: 11325790

D'Alessandro A, Benowitz NL, Muzi G, Eisner MD, Filiberto S, Fantozzi P, Montanari L, Abbritti G. Systemic nicotine exposure in tobacco harvesters. Archives of environmental health 2001. PMID: 11480503

Dempsey DA, Benowitz NL. Risks and benefits of nicotine to aid smoking cessation in pregnancy. Drug safety 2001. PMID: 11330657

Benowitz NL, Jacob P. Trans-3'-hydroxycotinine: disposition kinetics, effects and plasma levels during cigarette smoking. British journal of clinical pharmacology 2001. PMID: 11167665

Haller CA, Benowitz NL. Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids. The New England journal of medicine 2000. PMID: 11117974

Jacob P, Wu S, Yu L, Benowitz NL. Simultaneous determination of mecamylamine, nicotine, and cotinine in plasma by gas chromatography-mass spectrometry. Journal of pharmaceutical and biomedical analysis 2000. PMID: 10975241

Zevin S, Jacob P, Geppetti P, Benowitz NL. Clinical pharmacology of oral cotinine. Drug and alcohol dependence 2000. PMID: 10821985

Fattinger K, Benowitz NL, Jones RT, Verotta D. Nasal mucosal versus gastrointestinal absorption of nasally administered cocaine. European journal of clinical pharmacology 2000. PMID: 10954344

Jarvik ME, Madsen DC, Olmstead RE, Iwamoto-Schaap PN, Elins JL, Benowitz NL. Nicotine blood levels and subjective craving for cigarettes. Pharmacology, biochemistry, and behavior 2000. PMID: 10899369

Zevin S, Jacob P, Benowitz NL. Nicotine-mecamylamine interactions. Clinical pharmacology and therapeutics 2000. PMID: 10945316

Benowitz NL, Jacob P. Effects of cigarette smoking and carbon monoxide on nicotine and cotinine metabolism. Clinical pharmacology and therapeutics 2000. PMID: 10872647

Dempsey D, Jacob P, Benowitz NL. Nicotine metabolism and elimination kinetics in newborns. Clinical pharmacology and therapeutics 2000. PMID: 10824624

Drey EA, Thomas LJ, Benowitz NL, Goldschlager N, Darney PD. Safety of intra-amniotic digoxin administration before late second-trimester abortion by dilation and evacuation. American journal of obstetrics and gynecology 2000. PMID: 10819828

Chalon S, Moreno H, Benowitz NL, Hoffman BB, Blaschke TF. Nicotine impairs endothelium-dependent dilatation in human veins in vivo. Clinical pharmacology and therapeutics 2000. PMID: 10801248

Balfour D, Benowitz N, Fagerström K, Kunze M, Keil U. Diagnosis and treatment of nicotine dependence with emphasis on nicotine replacement therapy. A status report. European heart journal 2000. PMID: 10681484

Gourlay SG, Stead LF, Benowitz NL. Clonidine for smoking cessation. The Cochrane database of systematic reviews 2000. PMID: 10796479

Arciero PJ, Bougopoulos CL, Nindl BC, Benowitz NL. Influence of age on the thermic response to caffeine in women. Metabolism: clinical and experimental 2000. PMID: 10647072

Benowitz NL, Dempsey DA, Goldenberg RL, Hughes JR, Dolan-Mullen P, Ogburn PL, Oncken C, Orleans CT, Slotkin TA, Whiteside HP, Yaffe S. The use of pharmacotherapies for smoking cessation during pregnancy. Tobacco control 2000. PMID: 10982920

Benowitz NL, Perez-Stable EJ, Fong I, Modin G, Herrera B, Jacob P. Ethnic differences in N-glucuronidation of nicotine and cotinine. The Journal of pharmacology and experimental therapeutics 1999. PMID: 10565842

Benowitz NL. Snuff, nicotine and cardiovascular disease: implications for tobacco control. Journal of the American College of Cardiology 1999. PMID: 10577571

Sharp DS, Everhart JE, Benowitz NL. Coffee, alcohol, and the liver. Annals of epidemiology 1999. PMID: 10501405

Benowitz NL. Nicotine addiction. Primary care 1999. PMID: 10436290

Gelal A, Jacob P, Yu L, Benowitz NL. Disposition kinetics and effects of menthol. Clinical pharmacology and therapeutics 1999. PMID: 10460066

Zevin S, Benowitz NL. Drug interactions with tobacco smoking. An update. Clinical pharmacokinetics 1999. PMID: 10427467

Benowitz NL. Biomarkers of environmental tobacco smoke exposure. Environmental health perspectives 1999. PMID: 10350520

Jacob P, Yu L, Shulgin AT, Benowitz NL. Minor tobacco alkaloids as biomarkers for tobacco use: comparison of users of cigarettes, smokeless tobacco, cigars, and pipes. American journal of public health 1999. PMID: 10224986

Fenster L, Quale C, Waller K, Windham GC, Elkin EP, Benowitz N, Swan SH. Caffeine consumption and menstrual function. American journal of epidemiology 1999. PMID: 10084244

Elkin EP, Windham GC, Benowitz NL, Swan SH. Occasional smoking in a study of premenopausal women. American journal of public health 1999. PMID: 10076502

Benowitz NL. The biology of nicotine dependence: from the 1988 Surgeon General's Report to the present and into the future. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 1999. PMID: 11768175

Benowitz NL, Zevin S, Jacob P. Suppression of nicotine intake during ad libitum cigarette smoking by high-dose transdermal nicotine. The Journal of pharmacology and experimental therapeutics 1998. PMID: 9864279

Arciero PJ, Gardner AW, Benowitz NL, Poehlman ET. Relationship of blood pressure, heart rate and behavioral mood state to norepinephrine kinetics in younger and older men following caffeine ingestion. European journal of clinical nutrition 1998. PMID: 9846593

Benowitz NL, Hatsukami D. Gender differences in the pharmacology of nicotine addiction. Addiction biology 1998. PMID: 26735114

Zevin S, Gourlay SG, Benowitz NL. Clinical pharmacology of nicotine. Clinics in dermatology 1998. PMID: 9787965

Bernstein GA, Carroll ME, Dean NW, Crosby RD, Perwien AR, Benowitz NL. Caffeine withdrawal in normal school-age children. Journal of the American Academy of Child and Adolescent Psychiatry 1998. PMID: 9695448

Pérez-Stable EJ, Herrera B, Jacob P, Benowitz NL. Nicotine metabolism and intake in black and white smokers. JAMA 1998. PMID: 9669788

Zevin S, Jacob P, Benowitz NL. Dose-related cardiovascular and endocrine effects of transdermal nicotine. Clinical pharmacology and therapeutics 1998. PMID: 9695723

Winders SE, Grunberg NE, Benowitz NL, Alvares AP. Effects of stress on circulating nicotine and cotinine levels and in vitro nicotine metabolism in the rat. Psychopharmacology 1998. PMID: 9676899

Gries JM, Benowitz N, Verotta D. Importance of chronopharmacokinetics in design and evaluation of transdermal drug delivery systems. The Journal of pharmacology and experimental therapeutics 1998. PMID: 9580583

Fenster L, Quale C, Hiatt RA, Wilson M, Windham GC, Benowitz NL. Rate of caffeine metabolism and risk of spontaneous abortion. American journal of epidemiology 1998. PMID: 9525538

Denaro CP, Jacob P, Benowitz NL. Evaluation of pharmacokinetic methods used to estimate caffeine clearance and comparison with a Bayesian forecasting method. Therapeutic drug monitoring 1998. PMID: 9485560

Herzig KE, Callaway E, Halliday R, Naylor H, Benowitz NL. Effects of cotinine on information processing in nonsmokers. Psychopharmacology 1998. PMID: 9497017

Henningfield JE, Benowitz NL, Slade J, Houston TP, Davis RM, Deitchman SD. Reducing the addictiveness of cigarettes. Council on Scientific Affairs, American Medical Association. Tobacco control 1998. PMID: 9825424

Benowitz NL. Birthing of clinical pharmacologists. Clinical pharmacology and therapeutics 1997. PMID: 9433386

Benowitz NL, Jacob P, Slade J, Yu L. Nicotine content of the eclipse nicotine delivery device. American journal of public health 1997. PMID: 9366646

Benowitz NL. Treating tobacco addiction--nicotine or no nicotine? The New England journal of medicine 1997. PMID: 9337385

Gourlay SG, Benowitz NL. Arteriovenous differences in plasma concentration of nicotine and catecholamines and related cardiovascular effects after smoking, nicotine nasal spray, and intravenous nicotine. Clinical pharmacology and therapeutics 1997. PMID: 9357397

Fenster L, Hubbard AE, Swan SH, Windham GC, Waller K, Hiatt RA, Benowitz N. Caffeinated beverages, decaffeinated coffee, and spontaneous abortion. Epidemiology (Cambridge, Mass.) 1997. PMID: 9270953

Benowitz NL. Systemic absorption and effects of nicotine from smokeless tobacco. Advances in dental research 1997. PMID: 9524434

Zieman M, Fong SK, Benowitz NL, Banskter D, Darney PD. Absorption kinetics of misoprostol with oral or vaginal administration. Obstetrics and gynecology 1997. PMID: 9207820

Mahmarian JJ, Moyé LA, Nasser GA, Nagueh SF, Bloom MF, Benowitz NL, Verani MS, Byrd WG, Pratt CM. Nicotine patch therapy in smoking cessation reduces the extent of exercise-induced myocardial ischemia. Journal of the American College of Cardiology 1997. PMID: 9207632

Benowitz NL. The role of nicotine in smoking-related cardiovascular disease. Preventive medicine 1997. PMID: 9245658

Benowitz NL, Gourlay SG. Cardiovascular toxicity of nicotine: implications for nicotine replacement therapy. Journal of the American College of Cardiology 1997. PMID: 9180099

Zevin S, Jacob P, Benowitz N. Cotinine effects on nicotine metabolism. Clinical pharmacology and therapeutics 1997. PMID: 9209247

Fattinger K, Verotta D, Benowitz NL. Pharmacodynamics of acute tolerance to multiple nicotinic effects in humans. The Journal of pharmacology and experimental therapeutics 1997. PMID: 9190859

Heishman SJ, Balfour DJ, Benowitz NL, Hatsukami DK, Lindstrom JM, Ockene JK. Society for Research on Nicotine and Tobacco. Addiction (Abingdon, England) 1997. PMID: 9219386

Schneider NG, Jacob P, Nilsson F, Leischow SJ, Benowitz NL, Olmstead RE. Saliva cotinine levels as a function of collection method. Addiction (Abingdon, England) 1997. PMID: 9219396

Benowitz NL, Zevin S, Jacob P. Sources of variability in nicotine and cotinine levels with use of nicotine nasal spray, transdermal nicotine, and cigarette smoking. British journal of clinical pharmacology 1997. PMID: 9088580

Miao FJ, Benowitz NL, Heller PH, Levine JD. Contribution of adrenal hormones to nicotine-induced inhibition of synovial plasma extravasation in the rat. British journal of pharmacology 1997. PMID: 9117123

Gourlay SG, Benowitz NL, Forbes A, McNeil JJ. Determinants of plasma concentrations of nicotine and cotinine during cigarette smoking and transdermal nicotine treatment. European journal of clinical pharmacology 1997. PMID: 9049583

Benowitz NL, Jacob P. Individual differences in nicotine kinetics and metabolism in humans. NIDA research monograph 1997. PMID: 9260183

Burns D, Benowitz N, N'Connolly GN, Cummings KM, Davis RM, Henningfield JE, Shopland DR, Warner KE. What should be the elements of any settlement with the tobacco industry? Tobacco control 1997. PMID: 9176975

Gries JM, Benowitz N, Verotta D. Chronopharmacokinetics of nicotine. Clinical pharmacology and therapeutics 1996. PMID: 8873686

Benowitz NL, Zevin S, Carlsen S, Wright J, Schambelan M, Cheitlin M. Orthostatic hypertension due to vascular adrenergic hypersensitivity. Hypertension (Dallas, Tex. : 1979) 1996. PMID: 8675262

Gourlay SG, Benowitz NL. The benefits of stopping smoking and the role of nicotine replacement therapy in older patients. Drugs & aging 1996. PMID: 8818582

Benowitz NL, Jacob P, Perez-Stable E. CYP2D6 phenotype and the metabolism of nicotine and cotinine. Pharmacogenetics 1996. PMID: 8807663

Miao FJ, Benowitz N, Levine JD. Neural and endocrine circuits mediating inhibition of bradykinin-induced plasma extravasation by subcutaneous and spinal-intrathecal nicotine. The Journal of pharmacology and experimental therapeutics 1996. PMID: 8667217

Denaro CP, Wilson M, Jacob P, Benowitz NL. The effect of liver disease on urine caffeine metabolite ratios. Clinical pharmacology and therapeutics 1996. PMID: 8681487

Sachs DP, Benowitz NL. Individualizing medical treatment for tobacco dependence. The European respiratory journal 1996. PMID: 8726921

Hussain TF, Heidenreich PA, Benowitz N. Recurrent non-Q-wave myocardial infarction associated with toluene abuse. American heart journal 1996. PMID: 8604650

Denaro CP, Wilson M, Jacob P, Benowitz NL. Validation of urine caffeine metabolite ratios with use of stable isotope-labeled caffeine clearance. Clinical pharmacology and therapeutics 1996. PMID: 8653991

Mumford GK, Benowitz NL, Evans SM, Kaminski BJ, Preston KL, Sannerud CA, Silverman K, Griffiths RR. Absorption rate of methylxanthines following capsules, cola and chocolate. European journal of clinical pharmacology 1996. PMID: 9010706

Benowitz NL. Cotinine as a biomarker of environmental tobacco smoke exposure. Epidemiologic reviews 1996. PMID: 9021312

Walter FG, Bey TA, Ruschke DS, Benowitz NL. Marijuana and hyperthermia. Journal of toxicology. Clinical toxicology 1996. PMID: 8618257

Benowitz NL. Pharmacology of nicotine: addiction and therapeutics. Annual review of pharmacology and toxicology 1996. PMID: 8725403

Shusterman D, Alexeeff G, Hargis C, Kaplan J, Sato R, Gelb A, Becker C, Benowitz N, Gillen M, Thollaug S, Balmes J. Predictors of carbon monoxide and hydrogen cyanide exposure in smoke inhalation patients. Journal of toxicology. Clinical toxicology 1996. PMID: 8632515

Perkins KA, Benowitz N, Henningfield J, Newhouse P, Pomerleau O, Swan G. Society for Research on Nicotine and Tobacco. Addiction (Abingdon, England) 1996. PMID: 8822021

Kimmel SE, Benowitz N. Smoking cessation and the nicotine patch: much more to be done. Journal of general internal medicine 1995. PMID: 8770725

Benowitz NL, Jacob P, Mayan H, Denaro C. Sympathomimetic effects of paraxanthine and caffeine in humans. Clinical pharmacology and therapeutics 1995. PMID: 8529334

Sharp DS, Benowitz NL, Bath PM, Martin JF, Beswick AD, Elwood PC. Cigarette smoking sensitizes and desensitizes impedance-measured ADP-induced platelet aggregation in whole blood. Thrombosis and haemostasis 1995. PMID: 8585014

Gourlay SG, Benowitz NL. Is clonidine an effective smoking cessation therapy? Drugs 1995. PMID: 8521754

Arciero PJ, Gardner AW, Calles-Escandon J, Benowitz NL, Poehlman ET. Effects of caffeine ingestion on NE kinetics, fat oxidation, and energy expenditure in younger and older men. The American journal of physiology 1995. PMID: 7611396

Benowitz NL. Nicotine patches. BMJ (Clinical research ed.) 1995. PMID: 7646675

Benowitz NL, Jacob P, Sachs DP. Deficient C-oxidation of nicotine. Clinical pharmacology and therapeutics 1995. PMID: 7768082

Henningfield JE, Benowitz NL. Cigarettes and addiction. BMJ (Clinical research ed.) 1995. PMID: 7742663

Pérez-Stable EJ, Benowitz NL, Marín G. Is serum cotinine a better measure of cigarette smoking than self-report? Preventive medicine 1995. PMID: 7597020

Sharp DS, Benowitz NL. Re: "Alcohol, smoking, coffee, and cirrhosis" and "coffee and serum gamma-glutamyltransferase: a study of self-defense officials in Japan". American journal of epidemiology 1995. PMID: 7879794

Neese RA, Benowitz NL, Hoh R, Faix D, LaBua A, Pun K, Hellerstein MK. Metabolic interactions between surplus dietary energy intake and cigarette smoking or its cessation. The American journal of physiology 1994. PMID: 7810617

Benowitz NL, Jacob P. Metabolism of nicotine to cotinine studied by a dual stable isotope method. Clinical pharmacology and therapeutics 1994. PMID: 7955812

Chou TM, Benowitz NL. Caffeine and coffee: effects on health and cardiovascular disease. Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology 1994. PMID: 7881818

Sharp DS, Benowitz NL. Re: "Inconsistent associations of caffeine-containing beverages with blood pressure and with lipoproteins: the CARDIA Study". American journal of epidemiology 1994. PMID: 7980844

Miao FJ, Jänig W, Dallman MF, Benowitz NL, Heller PH, Basbaum AI, Levine JD. Role of vagal afferents and spinal pathways modulating inhibition of bradykinin-induced plasma extravasation by intrathecal nicotine. Journal of neurophysiology 1994. PMID: 7807204

Henningfield JE, Kozlowski LT, Benowitz NL. A proposal to develop meaningful labeling for cigarettes. JAMA 1994. PMID: 8028146

Benowitz NL, Henningfield JE. Establishing a nicotine threshold for addiction. The implications for tobacco regulation. The New England journal of medicine 1994. PMID: 7818638

Arcavi L, Jacob P, Hellerstein M, Benowitz NL. Divergent tolerance to metabolic and cardiovascular effects of nicotine in smokers with low and high levels of cigarette consumption. Clinical pharmacology and therapeutics 1994. PMID: 8033495

Benowitz NL, Leistikow B. Environmental tobacco smoke hazards and benefits of work-site nonsmoking programs. The Western journal of medicine 1994. PMID: 8053178

Le Houezec J, Halliday R, Benowitz NL, Callaway E, Naylor H, Herzig K. A low dose of subcutaneous nicotine improves information processing in non-smokers. Psychopharmacology 1994. PMID: 7855225

Olson KR, Kearney TE, Dyer JE, Benowitz NL, Blanc PD. Seizures associated with poisoning and drug overdose. Volume 12 of Issue 3. The American journal of emergency medicine 1994. PMID: 8179767

Bernstein GA, Carroll ME, Crosby RD, Perwien AR, Go FS, Benowitz NL. Caffeine effects on learning, performance, and anxiety in normal school-age children. Journal of the American Academy of Child and Adolescent Psychiatry 1994. PMID: 8169187

Hellerstein MK, Benowitz NL, Neese RA, Schwartz JM, Hoh R, Jacob P, Hsieh J, Faix D. Effects of cigarette smoking and its cessation on lipid metabolism and energy expenditure in heavy smokers. The Journal of clinical investigation 1994. PMID: 8282797

Benowitz NL, Jacob P, Fong I, Gupta S. Nicotine metabolic profile in man: comparison of cigarette smoking and transdermal nicotine. The Journal of pharmacology and experimental therapeutics 1994. PMID: 8301571

Olson KR, Kearney TE, Dyer JE, Benowitz NL, Blanc PD. Seizures associated with poisoning and drug overdose. The American journal of emergency medicine 1993. PMID: 8192750

Park SB, Jacob P, Benowitz NL, Cashman JR. Stereoselective metabolism of (S)-(-)-nicotine in humans: formation of trans-(S)-(-)-nicotine N-1'-oxide. Chemical research in toxicology 1993. PMID: 8117928

Benowitz NL, Fitzgerald GA, Wilson M, Zhang Q. Nicotine effects on eicosanoid formation and hemostatic function: comparison of transdermal nicotine and cigarette smoking. Journal of the American College of Cardiology 1993. PMID: 7691912

Rose JE, Levin ED, Benowitz N. Saliva nicotine as an index of plasma levels in nicotine skin patch users. Therapeutic drug monitoring 1993. PMID: 8249050

Jacob P, Yu L, Liang G, Shulgin AT, Benowitz NL. Gas chromatographic-mass spectrometric method for determination of anabasine, anatabine and other tobacco alkaloids in urine of smokers and smokeless tobacco users. Journal of chromatography 1993. PMID: 8245163

Gupta SK, Benowitz NL, Jacob P, Rolf CN, Gorsline J. Bioavailability and absorption kinetics of nicotine following application of a transdermal system. British journal of clinical pharmacology 1993. PMID: 9114908

Benowitz NL. Smoking-induced coronary vasoconstriction: implications for therapeutic use of nicotine. Journal of the American College of Cardiology 1993. PMID: 8354793

Arcavi L, Benowitz NL. Clinical significance of genetic influences on cardiovascular drug metabolism. Cardiovascular drugs and therapy 1993. PMID: 8103355

Henningfield JE, Stapleton JM, Benowitz NL, Grayson RF, London ED. Higher levels of nicotine in arterial than in venous blood after cigarette smoking. Drug and alcohol dependence 1993. PMID: 8370337

Lee BL, Wong D, Benowitz NL, Sullam PM. Altered patterns of drug metabolism in patients with acquired immunodeficiency syndrome. Clinical pharmacology and therapeutics 1993. PMID: 8491064

Benowitz NL, Jacob P. Nicotine and cotinine elimination pharmacokinetics in smokers and nonsmokers. Clinical pharmacology and therapeutics 1993. PMID: 8453850

Roll RL, Jones TA, Benowitz NL, Morley BJ. The chronic infusion of nicotine into the developing chick embryo does not alter the density of (-)-[3H]nicotine-binding sites or vestibular function. Brain research 1993. PMID: 8457853

Miao FJ, Dallman MF, Benowitz NL, Basbaum AI, Levine JD. Adrenal medullary modulation of the inhibition of bradykinin-induced plasma extravasation by intrathecal nicotine. The Journal of pharmacology and experimental therapeutics 1993. PMID: 8094755

Benowitz NL. Nicotine replacement therapy. What has been accomplished--can we do better? Drugs 1993. PMID: 7681369

Le Houezec J, Jacob P, Benowitz NL. A clinical pharmacological study of subcutaneous nicotine. European journal of clinical pharmacology 1993. PMID: 8491235

Benowitz NL. Clinical pharmacology and toxicology of cocaine. Pharmacology & toxicology 1993. PMID: 8441738

Forsyth JC, Mueller PD, Becker CE, Osterloh J, Benowitz NL, Rumack BH, Hall AH. Hydroxocobalamin as a cyanide antidote: safety, efficacy and pharmacokinetics in heavily smoking normal volunteers. Journal of toxicology. Clinical toxicology 1993. PMID: 8492341

Shi J, Benowitz NL, Denaro CP, Sheiner LB. Pharmacokinetic-pharmacodynamic modeling of caffeine: tolerance to pressor effects. Clinical pharmacology and therapeutics 1993. PMID: 8422743

Jacob P, Shulgin AT, Yu L, Benowitz NL. Determination of the nicotine metabolite trans-3'-hydroxycotinine in urine of smokers using gas chromatography with nitrogen-selective detection or selected ion monitoring. Journal of chromatography 1992. PMID: 1478978

Miao FJ, Helms C, Benowitz NL, Basbaum AI, Heller PH, Levine JD. Chronically administered nicotine attenuates bradykinin-induced plasma extravasation and aggravates arthritis-induced joint injury in the rat. Neuroscience 1992. PMID: 1362599

Geller RJ, Benowitz NL. Orthostatic hypotension in ciguatera fish poisoning. Archives of internal medicine 1992. PMID: 1417387

Benowitz NL. The genetics of drug dependence: tobacco addiction. The New England journal of medicine 1992. PMID: 1508249

Benowitz NL, Jacob P, Olsson P, Johansson CJ. Intravenous nicotine retards transdermal absorption of nicotine: evidence of blood flow--limited percutaneous absorption. Clinical pharmacology and therapeutics 1992. PMID: 1526077

Cashman JR, Park SB, Yang ZC, Wrighton SA, Jacob P, Benowitz NL. Metabolism of nicotine by human liver microsomes: stereoselective formation of trans-nicotine N'-oxide. Chemical research in toxicology 1992. PMID: 1446003

Miao FJ, Benowitz NL, Basbaum AI, Levine JD. Sympathoadrenal contribution to nicotinic and muscarinic modulation of bradykinin-induced plasma extravasation in the knee joint of the rat. The Journal of pharmacology and experimental therapeutics 1992. PMID: 1527731

Vestal RE, Benowitz NL. Workshop on problem-based learning as a method for teaching clinical pharmacology and therapeutics in medical school. Journal of clinical pharmacology 1992. PMID: 1430298

Benowitz NL. Cardiotoxicity in the workplace. Occupational medicine (Philadelphia, Pa.) 1992. PMID: 1496430

Benowitz NL. Cigarette smoking and nicotine addiction. The Medical clinics of North America 1992. PMID: 1548969

Siegel D, Benowitz N, Ernster VL, Grady DG, Hauck WW. Smokeless tobacco, cardiovascular risk factors, and nicotine and cotinine levels in professional baseball players. American journal of public health 1992. PMID: 1536359

Benowitz NL. How toxic is cocaine? Ciba Foundation symposium 1992. PMID: 1638909

Pérez-Stable EJ, Marín G, Marín BV, Benowitz NL. Misclassification of smoking status by self-reported cigarette consumption. The American review of respiratory disease 1992. PMID: 1731599

Henningfield JE, Obarzanek E, Benowitz NL, Hall SM, Klesges RC, Leischow S, Levin ED, Perkins KA, Spring B, Stitzer M. National working conference on smoking and body weight. Task Force 2: Methods of assessment, strategies for research. Health psychology : official journal of the Division of Health Psychology, American Psychological Association 1992. PMID: 1396498

Shiffman S, Zettler-Segal M, Kassel J, Paty J, Benowitz NL, O'Brien G. Nicotine elimination and tolerance in non-dependent cigarette smokers. Psychopharmacology 1992. PMID: 1365861

Benowitz NL. Nicotine replacement therapy during pregnancy. JAMA 1991. PMID: 1956108

Le Houezec J, Benowitz NL. Basic and clinical psychopharmacology of nicotine. Clinics in chest medicine 1991. PMID: 1747987

Benowitz NL. Nicotine and coronary heart disease. Trends in cardiovascular medicine 1991. PMID: 21239286

Pearigen PD, Benowitz NL. Poisoning due to calcium antagonists. Experience with verapamil, diltiazem and nifedipine. Drug safety 1991. PMID: 1793522

Benowitz NL, Jacob P. Nicotine metabolism in humans. Clinical pharmacology and therapeutics 1991. PMID: 1914383

Benowitz NL, Chan K, Denaro CP, Jacob P. Stable isotope method for studying transdermal drug absorption: the nicotine patch. Clinical pharmacology and therapeutics 1991. PMID: 1914363

Cheitlin MD, Byrd R, Benowitz N, Liu E, Modin G. Amiloride improves hemodynamics in patients with chronic congestive heart failure treated with chronic digoxin and diuretics. Cardiovascular drugs and therapy 1991. PMID: 1888694

Duan MJ, Yu L, Savanapridi C, Jacob P, Benowitz NL. Disposition kinetics and metabolism of nicotine-1'-N-oxide in rabbits. Drug metabolism and disposition: the biological fate of chemicals 1991. PMID: 1680635

Benowitz NL. Pharmacodynamics of nicotine: implications for rational treatment of nicotine addiction. British journal of addiction 1991. PMID: 1859911

Jacob P, Yu L, Wilson M, Benowitz NL. Selected ion monitoring method for determination of nicotine, cotinine and deuterium-labeled analogs: absence of an isotope effect in the clearance of (S)-nicotine-3',3'-d2 in humans. Biological mass spectrometry 1991. PMID: 1883864

Jones CJ, Schiffman MH, Kurman R, Jacob P, Benowitz NL. Elevated nicotine levels in cervical lavages from passive smokers. American journal of public health 1991. PMID: 1994747

Benowitz NL, Jacob P, Denaro C, Jenkins R. Stable isotope studies of nicotine kinetics and bioavailability. Clinical pharmacology and therapeutics 1991. PMID: 2007322

Denaro CP, Brown CR, Jacob P, Benowitz NL. Effects of caffeine with repeated dosing. European journal of clinical pharmacology 1991. PMID: 2060564

Kim SY, Benowitz NL. Poisoning due to class IA antiarrhythmic drugs. Quinidine, procainamide and disopyramide. Drug safety 1990. PMID: 2285495

Benowitz NL, Jacob P. Nicotine metabolism in nonsmokers. Clinical pharmacology and therapeutics 1990. PMID: 2225708

Medina I, Mills J, Leoung G, Hopewell PC, Lee B, Modin G, Benowitz N, Wofsy CB. Oral therapy for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. A controlled trial of trimethoprim-sulfamethoxazole versus trimethoprim-dapsone. The New England journal of medicine 1990. PMID: 2392131

Pérez-Stable EJ, Marín BV, Marín G, Brody DJ, Benowitz NL. Apparent underreporting of cigarette consumption among Mexican American smokers. American journal of public health 1990. PMID: 2382741

Denaro CP, Brown CR, Wilson M, Jacob P, Benowitz NL. Dose-dependency of caffeine metabolism with repeated dosing. Clinical pharmacology and therapeutics 1990. PMID: 2401126

Benowitz NL, Jacob P. Intravenous nicotine replacement suppresses nicotine intake from cigarette smoking. The Journal of pharmacology and experimental therapeutics 1990. PMID: 2203896

Mueller PD, Benowitz NL, Olson KR. Cocaine. Emergency medicine clinics of North America 1990. PMID: 2201516

Ernster VL, Grady DG, Greene JC, Walsh M, Robertson P, Daniels TE, Benowitz N, Siegel D, Gerbert B, Hauck WW. Smokeless tobacco use and health effects among baseball players. JAMA 1990. PMID: 2355443

Jacob P, Shulgin AT, Benowitz NL. Synthesis of (3'R,5'S)-trans-3'-hydroxycotinine, a major metabolite of nicotine. Metabolic formation of 3'-hydroxycotinine in humans is highly stereoselective. Journal of medicinal chemistry 1990. PMID: 2362266

Benowitz NL. Diagnosis and management of pheochromocytoma. Hospital practice (Office ed.) 1990. PMID: 2112143

Kirch DG, Taylor TR, Gerhardt GA, Benowitz NL, Stephen C, Wyatt RJ. Effect of chronic caffeine administration on monoamine and monoamine metabolite concentrations in rat brain. Neuropharmacology 1990. PMID: 2385331

Sharp DS, Benowitz NL, Osterloh JD, Becker CE, Smith AH, Syme SL. Influence of race, tobacco use, and caffeine use on the relation between blood pressure and blood lead concentration. American journal of epidemiology 1990. PMID: 2321627

Henningfield JE, London ED, Benowitz NL. Arterial-venous differences in plasma concentrations of nicotine after cigarette smoking. JAMA 1990. PMID: 2319665

Shiffman S, Fischer LB, Zettler-Segal M, Benowitz NL. Nicotine exposure among nondependent smokers. Archives of general psychiatry 1990. PMID: 2322084

Zhang Y, Jacob P, Benowitz NL. Determination of nornicotine in smokers' urine by gas chromatography following reductive alkylation to N'-propylnornicotine. Journal of chromatography 1990. PMID: 2329163

Benowitz NL. Clinical pharmacology of caffeine. Annual review of medicine 1990. PMID: 2184730

Benowitz NL. Clinical pharmacology of inhaled drugs of abuse: implications in understanding nicotine dependence. NIDA research monograph 1990. PMID: 2267009

Jacob P, Jones RT, Benowitz NL, Shulgin AT, Lewis ER, Elias-Baker BA. Cocaine smokers excrete a pyrolysis product, anhydroecgonine methyl ester. Journal of toxicology. Clinical toxicology 1990. PMID: 2381018

Sharp DS, Benowitz NL. Pharmacoepidemiology of the effect of caffeine on blood pressure. Clinical pharmacology and therapeutics 1990. PMID: 2295220

Benowitz NL. Pharmacokinetic considerations in understanding nicotine dependence. Ciba Foundation symposium 1990. PMID: 2209254

Benowitz NL. Pheochromocytoma. Advances in internal medicine 1990. PMID: 2405593

Brown CR, Benowitz NL. Caffeine and cigarette smoking: behavioral, cardiovascular, and metabolic interactions. Pharmacology, biochemistry, and behavior 1989. PMID: 2623013

Benowitz NL, Sharp DS. Inverse relation between serum cotinine concentration and blood pressure in cigarette smokers. Circulation 1989. PMID: 2805267

Denaro CP, Benowitz NL. Poisoning due to class 1B antiarrhythmic drugs. Lignocaine, mexiletine and tocainide. Medical toxicology and adverse drug experience 1989. PMID: 2513464

Matsunga SK, Plezia PM, Karol MD, Katz MD, Camilli AE, Benowitz NL. Effects of passive smoking on theophylline clearance. Clinical pharmacology and therapeutics 1989. PMID: 2791443

Lee BL, Jacob P, Benowitz NL. Sulfonium salts as derivatizing agents. 2. Determination of theophylline in plasma by automated gas chromatography. Journal of chromatography 1989. PMID: 2584311

Mueller PD, Benowitz NL. Toxicologic causes of acute abdominal disorders. Emergency medicine clinics of North America 1989. PMID: 2663462

Benowitz NL, Jacob P, Yu L. Daily use of smokeless tobacco: systemic effects. Annals of internal medicine 1989. PMID: 2742246

Lee BL, Jacob P, Jarvik ME, Benowitz NL. Food and nicotine metabolism. Pharmacology, biochemistry, and behavior 1989. PMID: 2587604

Benowitz NL. Health and public policy implications of the "low yield" cigarette. The New England journal of medicine 1989. PMID: 2725602

Denaro C, Benowitz N. Diabetic patients and hepatic drug metabolism. Clinical pharmacology and therapeutics 1989. PMID: 2731408

Benowitz NL, Hall SM, Modin G. Persistent increase in caffeine concentrations in people who stop smoking. BMJ (Clinical research ed.) 1989. PMID: 2497897

Lee BL, Medina I, Benowitz NL, Jacob P, Wofsy CB, Mills J. Dapsone, trimethoprim, and sulfamethoxazole plasma levels during treatment of Pneumocystis pneumonia in patients with the acquired immunodeficiency syndrome (AIDS). Evidence of drug interactions. Annals of internal medicine 1989. PMID: 2784648

Cherek DR, Bennett RH, Kelly TH, Steinberg JL, Benowitz NL. Effects of nicotine gum and tobacco smoking on human avoidance responding. Pharmacology, biochemistry, and behavior 1989. PMID: 2740422

Hall SM, McGee R, Tunstall C, Duffy J, Benowitz N. Changes in food intake and activity after quitting smoking. Journal of consulting and clinical psychology 1989. PMID: 2925977

Sachs DP, Benowitz N. Are smokers trying to stop and smokers not trying to stop the same experimental model? NIDA research monograph 1989. PMID: 2701304

Benowitz NL, Porchet H, Jacob P. Nicotine dependence and tolerance in man: pharmacokinetic and pharmacodynamic investigations. Progress in brain research 1989. PMID: 2587748

Benowitz NL, Lee BL, Jacob P. Nicotine gum and theophylline metabolism. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 1989. PMID: 2730948

Benowitz NL. Drug therapy. Pharmacologic aspects of cigarette smoking and nicotine addiction. The New England journal of medicine 1988. PMID: 3054551

Benowitz NL. Sodium intake from smokeless tobacco. The New England journal of medicine 1988. PMID: 3412420

Benowitz NL, Porchet H, Sheiner L, Jacob P. Nicotine absorption and cardiovascular effects with smokeless tobacco use: comparison with cigarettes and nicotine gum. Clinical pharmacology and therapeutics 1988. PMID: 3391001

Benowitz NL. Nicotine and smokeless tobacco. CA: a cancer journal for clinicians 1988. PMID: 3135084

Wall MA, Johnson J, Jacob P, Benowitz NL. Cotinine in the serum, saliva, and urine of nonsmokers, passive smokers, and active smokers. American journal of public health 1988. PMID: 3369604

Jarvis MJ, Russell MA, Benowitz NL, Feyerabend C. Elimination of cotinine from body fluids: implications for noninvasive measurement of tobacco smoke exposure. American journal of public health 1988. PMID: 3369603

Brown CR, Jacob P, Wilson M, Benowitz NL. Changes in rate and pattern of caffeine metabolism after cigarette abstinence. Clinical pharmacology and therapeutics 1988. PMID: 3365914

Jacob P, Benowitz NL, Copeland JR, Risner ME, Cone EJ. Disposition kinetics of nicotine and cotinine enantiomers in rabbits and beagle dogs. Journal of pharmaceutical sciences 1988. PMID: 3411460

Benowitz NL. Pheochromocytoma--recent advances in diagnosis and treatment. The Western journal of medicine 1988. PMID: 3176460

Jacob P, Benowitz NL, Shulgin AT. Recent studies of nicotine metabolism in humans. Pharmacology, biochemistry, and behavior 1988. PMID: 3174750

Nemeth-Coslett R, Benowitz NL, Robinson N, Henningfield JE. Nicotine gum: chew rate, subjective effects and plasma nicotine. Pharmacology, biochemistry, and behavior 1988. PMID: 3413200

Risner ME, Cone EJ, Benowitz NL, Jacob P. Effects of the stereoisomers of nicotine and nornicotine on schedule-controlled responding and physiological parameters of dogs. The Journal of pharmacology and experimental therapeutics 1988. PMID: 3252033

Myers MG, Benowitz NL, Dubbin JD, Haynes RB, Sole MJ. Cardiovascular effects of smoking in patients with ischemic heart disease. Chest 1988. PMID: 3335145

Porchet HC, Benowitz NL, Sheiner LB. Pharmacodynamic model of tolerance: application to nicotine. The Journal of pharmacology and experimental therapeutics 1988. PMID: 3336000

Benowitz NL. Toxicity of nicotine: implications with regard to nicotine replacement therapy. Progress in clinical and biological research 1988. PMID: 3289005

Shulgin AT, Jacob P, Benowitz NL, Lau D. Identification and quantitative analysis of cotinine-N-oxide in human urine. Journal of chromatography 1987. PMID: 3443673

Simon RP, Copeland JR, Benowitz NL, Jacob P, Bronstein J. Brain phenobarbital uptake during prolonged status epilepticus. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1987. PMID: 3693434

Porchet HC, Benowitz NL, Sheiner LB, Copeland JR. Apparent tolerance to the acute effect of nicotine results in part from distribution kinetics. The Journal of clinical investigation 1987. PMID: 3680508

Peters RW, Benowitz NL, Valenti S, Modin G, Fisher ML. Electrophysiologic effects of cigarette smoking in patients with and without chronic beta-blocker therapy. The American journal of cardiology 1987. PMID: 2890291

Lynch CJ, Benowitz NL. Spontaneous cigarette brand switching: consequences for nicotine and carbon monoxide exposure. American journal of public health 1987. PMID: 3618852

Hall SM, Tunstall CD, Ginsberg D, Benowitz NL, Jones RT. Nicotine gum and behavioral treatment: a placebo controlled trial. Volume 55 of Issue 4. Journal of consulting and clinical psychology 1987. PMID: 3624619

Juenemann KP, Lue TF, Luo JA, Benowitz NL, Abozeid M, Tanagho EA. The effect of cigarette smoking on penile erection. The Journal of urology 1987. PMID: 3599273

Jacob P, Elias-Baker BA, Jones RT, Benowitz NL. Determination of benzoylecgonine and cocaine in biologic fluids by automated gas chromatography. Journal of chromatography 1987. PMID: 3654881

Benowitz NL, Lake T, Keller KH, Lee BL. Prolonged absorption with development of tolerance to toxic effects after cutaneous exposure to nicotine. Clinical pharmacology and therapeutics 1987. PMID: 3595064

Lee BL, Benowitz NL, Jacob P. Cigarette abstinence, nicotine gum, and theophylline disposition. Annals of internal medicine 1987. PMID: 3826954

Benowitz NL, Jacob P, Savanapridi C. Determinants of nicotine intake while chewing nicotine polacrilex gum. Clinical pharmacology and therapeutics 1987. PMID: 3829583

Lee BL, Benowitz NL, Jacob P. Influence of tobacco abstinence on the disposition kinetics and effects of nicotine. Clinical pharmacology and therapeutics 1987. PMID: 3829584

Gori GB, Benowitz NL, Lynch CJ. Mouth versus deep airways absorption of nicotine in cigarette smokers. Pharmacology, biochemistry, and behavior 1986. PMID: 3809219

Benowitz NL, Jacob P, Kozlowski LT, Yu L. Influence of smoking fewer cigarettes on exposure to tar, nicotine, and carbon monoxide. The New England journal of medicine 1986. PMID: 3773954

Rosenberg J, Pentel P, Pond S, Benowitz N, Olson K. Hyperthermia associated with drug intoxication. Critical care medicine 1986. PMID: 3769509

Benowitz NL, Jones RT, Jacob P. Additive cardiovascular effects of nicotine and ethanol. Clinical pharmacology and therapeutics 1986. PMID: 3757405

Jacob P, Benowitz NL, Yu L, Shulgin AT. Determination of nicotine N-oxide by gas chromatography following thermal conversion to 2-methyl-6-(3-pyridyl)tetrahydro-1,2-oxazine. Analytical chemistry 1986. PMID: 3766974

Benowitz NL, Jacob P, Yu L, Talcott R, Hall S, Jones RT. Reduced tar, nicotine, and carbon monoxide exposure while smoking ultralow- but not low-yield cigarettes. JAMA 1986. PMID: 3723711

Pentel PR, Benowitz NL. Tricyclic antidepressant poisoning. Management of arrhythmias. Medical Toxicology 1986. PMID: 3784839

Benowitz NL, Simon RP, Copeland JR. Status epilepticus: divergence of sympathetic activity and cardiovascular response. Annals of neurology 1986. PMID: 3963763

Benowitz NL. Clinical pharmacology of nicotine. Annual review of medicine 1986. PMID: 3518606

Pomerleau OF, Bell CS, Benowitz NL, Best JA, Glassman A, Russell M, Russell P, Schneider NG. Nicotine and smoking relapse. Health psychology : official journal of the Division of Health Psychology, American Psychological Association 1986. PMID: 3582324

Simon RP, Benowitz N, Hedlund R, Copeland J. Influence of the blood-brain pH gradient on brain phenobarbital uptake during status epilepticus. The Journal of pharmacology and experimental therapeutics 1985. PMID: 4032292

Olson KR, Benowitz NL, Woo OF, Pond SM. Theophylline overdose: acute single ingestion versus chronic repeated overmedication. The American journal of emergency medicine 1985. PMID: 4041188

Benowitz NL, Jacob P. Nicotine renal excretion rate influences nicotine intake during cigarette smoking. The Journal of pharmacology and experimental therapeutics 1985. PMID: 4009497

Woo OF, Benowitz NL, Bialy FW, Wengert JW. Atrioventricular conduction block caused by phenylpropanolamine. JAMA 1985. PMID: 3989943

Pentel PR, Asinger RW, Benowitz NL. Propranolol antagonism of phenylpropanolamine-induced hypertension. Clinical pharmacology and therapeutics 1985. PMID: 3987172

Pond SM, Kreek MJ, Tong TG, Raghunath J, Benowitz NL. Altered methadone pharmacokinetics in methadone-maintained pregnant women. The Journal of pharmacology and experimental therapeutics 1985. PMID: 3981450

Hall SM, Tunstall C, Rugg D, Jones RT, Benowitz N. Nicotine gum and behavioral treatment in smoking cessation. Journal of consulting and clinical psychology 1985. PMID: 3998252

Rowbotham MC, Jones RT, Benowitz NL, Jacob P. Trazodone-oral cocaine interactions. Archives of general psychiatry 1984. PMID: 6380447

Olson KR, Benowitz NL. Environmental and drug-induced hyperthermia. Pathophysiology, recognition, and management. Emergency medicine clinics of North America 1984. PMID: 6534737

Jacob P, Savanapridi C, Yu L, Wilson M, Shulgin AT, Benowitz NL, Elias-Baker BA, Hall SM, Herning RI, Jones RT. Ion-pair extraction of thiocyanate from plasma and its gas chromatographic determination using on-column alkylation. Analytical chemistry 1984. PMID: 6486450

Benowitz NL, Jacob P. Nicotine and carbon monoxide intake from high- and low-yield cigarettes. Clinical pharmacology and therapeutics 1984. PMID: 6744784

Hall RG, Sachs DP, Hall SM, Benowitz NL. Two-year efficacy and safety of rapid smoking therapy in patients with cardiac and pulmonary disease. Journal of consulting and clinical psychology 1984. PMID: 6470283

Pentel P, Benowitz N. Efficacy and mechanism of action of sodium bicarbonate in the treatment of desipramine toxicity in rats. The Journal of pharmacology and experimental therapeutics 1984. PMID: 6086872

Benowitz NL, Kuyt F, Jacob P. Influence of nicotine on cardiovascular and hormonal effects of cigarette smoking. Clinical pharmacology and therapeutics 1984. PMID: 6734053

Pentel P, Benowitz N. Pharmacokinetic and pharmacodynamic considerations in drug therapy of cardiac emergencies. Clinical pharmacokinetics 1984. PMID: 6380870

Inouye IK, Massie BM, Benowitz N, Simpson P, Loge D. Antihypertensive therapy with diltiazem and comparison with hydrochlorothiazide. The American journal of cardiology 1984. PMID: 6375339

Hall SM, Herning RI, Jones RT, Benowitz NL, Jacob P. Blood cotinine levels as indicators of smoking treatment outcome. Clinical pharmacology and therapeutics 1984. PMID: 6734033

Benowitz NL, Jacob P. Daily intake of nicotine during cigarette smoking. Clinical pharmacology and therapeutics 1984. PMID: 6705448

Jacob P, Elias-Baker BA, Jones RT, Benowitz NL. Determination of cocaine in plasma by automated gas chromatography. Journal of chromatography 1984. PMID: 6715457

Simon RP, Benowitz NL, Culala S. Motor paralysis increases brain uptake of lidocaine during status epilepticus. Neurology 1984. PMID: 6538283

Simon RP, Aminoff MJ, Benowitz NL. Changes in plasma catecholamines after tonic-clonic seizures. Neurology 1984. PMID: 6538024

Inouye I, Massie B, Benowitz N, Simpson P, Loge D, Topic N. Monotherapy in mild to moderate hypertension: comparison of hydrochlorothiazide, propranolol and prazosin. The American journal of cardiology 1984. PMID: 6320622

Woo OF, Pond SM, Benowitz NL, Olson KR. Benefit of hemoperfusion in acute theophylline intoxication. Journal of toxicology. Clinical toxicology 1984. PMID: 6530699

Meister W, Benowitz NL, Benet LZ. Unchanged absorption of digoxin tablets in patients with cardiac failure. Pharmacology 1984. PMID: 6709691

Levine J, Gordon NC, Poole T, Benowitz N. Relationship of duration of analgesia to opioid pharmacokinetic variables. Brain research 1983. PMID: 6318904

Hargreaves WA, Tyler J, Weinberg JA, Sorensen JL, Benowitz N. (--)-alpha-Acetylmethadol effects on alcohol and diazepam use, sexual function and cardiac function. Drug and alcohol dependence 1983. PMID: 6671416

Benowitz NL, Kuyt F, Jacob P, Jones RT, Osman AL. Cotinine disposition and effects. Clinical pharmacology and therapeutics 1983. PMID: 6627820

Olson K, Benowitz NL, Pentel P. Management of cocaine poisoning. Annals of emergency medicine 1983. PMID: 6625275

Kirby BD, Ham J, Fairley HB, Benowitz N, Schambelan M. Normotensive pheochromocytoma. Pharmacologic, paraneoplastic and anesthetic considerations. The Western journal of medicine 1983. PMID: 6636736

Benowitz NL, Hall SM, Herning RI, Jacob P, Jones RT, Osman AL. Smokers of low-yield cigarettes do not consume less nicotine. The New England journal of medicine 1983. PMID: 6866013

Olson KR, Pond SM, Benowitz NL, Becker CE. Treatment of theophylline overdose. JAMA 1983. PMID: 6854843

Foliart D, Benowitz NL, Becker CE. Passive absorption of nicotine in airline flight attendants. The New England journal of medicine 1983. PMID: 6835330

Pentel P, Olson KR, Becker CE, Benowitz N. Late complications of tricyclic antidepressant overdose. The Western journal of medicine 1983. PMID: 6858131

Herning RI, Jones RT, Benowitz NL, Mines AH. How a cigarette is smoked determines blood nicotine levels. Clinical pharmacology and therapeutics 1983. PMID: 6848303

Benowitz NL. The use of biologic fluid samples in assessing tobacco smoke consumption. NIDA research monograph 1983. PMID: 6443145

Benowitz NL, Kuyt F, Jacob P. Circadian blood nicotine concentrations during cigarette smoking. Clinical pharmacology and therapeutics 1982. PMID: 7140139

Benowitz NL, Osterloh J, Goldschlager N, Kaysen G, Pond S, Forhan S. Massive catecholamine release from caffeine poisoning. JAMA 1982. PMID: 7109204

Benowitz NL, Jacob P, Jones RT, Rosenberg J. Interindividual variability in the metabolism and cardiovascular effects of nicotine in man. The Journal of pharmacology and experimental therapeutics 1982. PMID: 7077531

Jacob P, Rigod JF, Pond SM, Benowitz NL. Gas chromatographic analysis of meperidine and normeperidine: determination in blood after a single dose of meperidine. Journal of pharmaceutical sciences 1982. PMID: 7062237

Simon RP, Benowitz NL, Bronstein J, Jacob P. Increased brain uptake of lidocaine during bicuculline-induced status epilepticus in rats. Neurology 1982. PMID: 7198745

Pond SM, Tong TG, Benowitz NL, Jacob P, Rigod J. Lack of effect of diazepam on methadone metabolism in methadone-maintained addicts. Clinical pharmacology and therapeutics 1982. PMID: 7056020

Cogan JJ, Humphreys MH, Carlson CJ, Benowitz NL, Rapaport E. Acute vasodilator therapy increases renal clearance of digoxin in patients with congestive heart failure. Circulation 1981. PMID: 7285311

Jacob P, Rigod JF, Pond SM, Benowitz NL. Determination of methadone and its primary metabolite in biologic fluids using gas chromatography with nitrogen-phosphorus detection. Journal of analytical toxicology 1981. PMID: 7339214

Benowitz NL, Jones RT. Cardiovascular and metabolic considerations in prolonged cannabinoid administration in man. Journal of clinical pharmacology 1981. PMID: 6271827

Jones RT, Benowitz NL, Herning RI. Clinical relevance of cannabis tolerance and dependence. Journal of clinical pharmacology 1981. PMID: 6271820

Gritz ER, Baer-Weiss V, Benowitz NL, Van Vunakis H, Jarvik ME. Plasma nicotine and cotinine concentrations in habitual smokeless tobacco users. Clinical pharmacology and therapeutics 1981. PMID: 7195786

Pond SM, Tong T, Benowitz NL, Jacob P, Rigod J. Presystemic metabolism of meperidine to normeperidine in normal and cirrhotic subjects. Clinical pharmacology and therapeutics 1981. PMID: 7249503

Rosenberg J, Benowitz NL, Pond S. Pharmacokinetics of drug overdose. Clinical pharmacokinetics 1981. PMID: 7016383

Tong TG, Pond SM, Kreek MJ, Jaffery NF, Benowitz NL. Phenytoin-induced methadone withdrawal. Annals of internal medicine 1981. PMID: 7224382

Fredericks AB, Benowitz NL, Savanapridi CY. The cardiovascular and autonomic effects of repeated administration of delta-9-tetrahydrocannabinol to rhesus monkeys. The Journal of pharmacology and experimental therapeutics 1981. PMID: 6257883

Jacob P, Wilson M, Benowitz NL. Improved gas chromatographic method for the determination of nicotine and cotinine in biologic fluids. Journal of chromatography 1981. PMID: 6783675

Peters KS, Tong TG, Kutz K, Benowitz NL. Diabetes mellitus and orthostatic hypotension resulting from ingestion of Vacor rat poison: endocrine and autonomic function studies. The Western journal of medicine 1981. PMID: 7210664

Rosenberg J, Benowitz NL, Jacob P, Wilson KM. Disposition kinetics and effects of intravenous nicotine. Clinical pharmacology and therapeutics 1980. PMID: 7408411

Pond SM, Tong T, Benowitz NL, Jacob P. Enhanced bioavailability of pethidine and pentazocine in patients with cirrhosis of the liver. Australian and New Zealand journal of medicine 1980. PMID: 6937164

Tong TG, Benowitz NL, Kreek MJ. Methadone-disulfiram interaction during methadone maintenance. Journal of clinical pharmacology 1980. PMID: 7430415

Benowitz NL, Nguyen TL, Jones RT, Herning RI, Bachman J. Metabolic and psychophysiologic studies of cannabidiol-hexobarbital interaction. Clinical pharmacology and therapeutics 1980. PMID: 7389248

Benowitz NL, Byrd R, Schambelan M, Rosenberg J, Roizen MF. Dihydroergotamine treatment for orthostatic hypotension from Vacor rodenticide. Annals of internal medicine 1980. PMID: 7356234

Benowitz NL, Rosenberg J, Pond S. Resin hemoperfusion for ethchlorvynol. Annals of internal medicine 1980. PMID: 7356245

Benowitz N, Abolin C, Tozer T, Rosenberg J, Rogers W, Pond S, Schoenfeld P, Humphreys M. Resin hemoperfusion in ethychlorvynol overdose. Clinical pharmacology and therapeutics 1980. PMID: 7353346

Fredericks AB, Benowitz NL. An abstinence syndrome following chronic administration of delta-9-terahydrocannabinol in rhesus monkeys. Psychopharmacology 1980. PMID: 6255508

Pond S, Rosenberg J, Benowitz NL, Takki S. Pharmacokinetics of haemoperfusion for drug overdose. Clinical pharmacokinetics 1979. PMID: 389527

Peeke SC, Prael AR, Herning RI, Rogers W, Benowitz NL, Jones RT. Effect of disulfiram on cognition, subjective response, and cortical-event-related potentials in nonalcoholic subjects. Alcoholism, clinical and experimental research 1979. PMID: 384831

Pond SM, Phillips M, Benowitz NL, Galinsky RE, Tong TG, Becker CE. Diazepam kinetics in acute alcohol withdrawal. Clinical pharmacology and therapeutics 1979. PMID: 445950

Benowitz NL, Rosenberg J, Rogers W, Bachman J, Jones RT. Cardiovascular effects of intravenous delta-9-tetrahydrocannabinol: autonomic nervous mechanisms. Clinical pharmacology and therapeutics 1979. PMID: 428189

Rogers WK, Benowitz NL, Wilson KM, Abbott JA. Effect of disulfiram on adrenergic function. Clinical pharmacology and therapeutics 1979. PMID: 106999

Bachman JA, Benowitz NL, Herning RI, Jones RT. Dissociation of autonomic and cognitive effects of THC in man. Psychopharmacology 1979. PMID: 108734

Ayus JC, Eneas JF, Tong TG, Benowitz NL, Schoenfeld PY, Hadley KL, Becker CE, Humphreys MH. Peritoneal clearance and total body elimination of vancomycin during chronic intermittent peritoneal dialysis. Clinical nephrology 1979. PMID: 436339

Benowitz NL, Rosenberg J, Becker CE. Cardiopulmonary catastrophes in drug-overdosed patients. The Medical clinics of North America 1979. PMID: 431195

Becker CE, Benowitz NL. Hypertensive emergencies. The Medical clinics of North America 1979. PMID: 431188

Benowitz NL, Meister W. Clinical pharmacokinetics of lignocaine. Clinical pharmacokinetics 1978. PMID: 350470

Benowitz NL, Jones RT. Effects of delta-9-tetrahydrocannabinol on drug distribution and metabolism. Antipyrine, pentobarbital, and ethanol. Clinical pharmacology and therapeutics 1977. PMID: 891094

Benowitz NL, Jones RT. Prolonged delta-9-tetrahydrocannabinol ingestion. Effects of sympathomimetic amines and autonomic blockades. Clinical pharmacology and therapeutics 1977. PMID: 837652

Benowitz NL, Meister W. Pharmacokinetics in patients with cardiac failure. Clinical pharmacokinetics 1976. PMID: 799548

Lau RJ, Tubergen DG, Barr M, Domino EF, Benowitz N, Jones RT. Phytohemagglutinin-induced lymphocyte transformation in humans receiving delta9-tetrahydrocannabinol. Science (New York, N.Y.) 1976. PMID: 1265484

Benowitz NL, Jones RT, Lerner CB. Depression of growth hormone and cortisol response to insulin-induced hypoglycemia after prolonged oral delta-9-tetrahydrocannabinol administration in man. The Journal of clinical endocrinology and metabolism 1976. PMID: 1270583

Teramo K, Benowitz N, Heymann MA, Rudolph AM. Gestational differences in lidocaine toxicity in the fetal lamb. Anesthesiology 1976. PMID: 1252020

Jones RT, Benowitz N, Bachman J. Clinical studies of cannabis tolerance and dependence. Annals of the New York Academy of Sciences 1976. PMID: 798533

Tong TG, Benowitz NL, Becker CE, Forni PJ, Boerner U. Phencyclidine poisoning. JAMA 1975. PMID: 1242170

Benowitz NL, Jones RT. Cardiovascular effects of prolonged delta-9-tetrahydrocannabinol ingestion. Clinical pharmacology and therapeutics 1975. PMID: 1164818

Galinsky RE, Forni PJ, McGuire GG, Tong TG, Benowitz N, Becker CE. Letter: "Post hoc" and hypoprothrombinemia. Annals of internal medicine 1975. PMID: 1147473

Benowitz N, Forsyth FP, Melmon KL, Rowland M. Lidocaine disposition kinetics in monkey and man. I. Prediction by a perfusion model. Clinical pharmacology and therapeutics 1974. PMID: 4210516

Benowitz N, Forsyth RP, Melmon KL, Rowland M. Lidocaine disposition kinetics in monkey and man. II. Effects of hemorrhage and sympathomimetic drug administration. Clinical pharmacology and therapeutics 1974. PMID: 4210517

Teramo K, Benowitz N, Heymann MA, Kahanpää K, Siimes A, Rudolph AM. Effects of lidocaine on heart rate, blood pressure, and electrocorticogram in fetal sheep. American journal of obstetrics and gynecology 1974. PMID: 4818426

Scheinman MM, Weiss AN, Shafton E, Benowitz N, Rowland M. Electrophysiologic effects of procaine amide in patients with intraventricular conduction delay. Circulation 1974. PMID: 4591547

Benowitz NL. Clinical applications of the pharmacokinetics of lidocaine. Cardiovascular clinics 1974. PMID: 4613465

Benowitz N, Rowland M. Determination of lidocaine in blood and tissues. Anesthesiology 1973. PMID: 4202543

Benowitz NL, Terepka AR. Calcium binding to phosphoprotein in estrogenized rooster plasma studied by density-gradient centrifugation. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1968. PMID: 5686540