Peter Ganz

Professor

Dr. Ganz is Director of the Center of Excellence in Vascular Research at the Zuckerberg San Francisco General Hospital. He is also the Maurice Eliaser Distinguished Professor of Medicine at the University of California, San Francisco. Dr. Ganz has been a pioneer and a leader in translational and clinical cardiovascular research. His laboratory was the first to describe vascular endothelial function in the state of health and endothelial dysfunction in atherosclerosis in humans (N Engl J Med 1986; 315:1046-1051). He identified risk factors associated with endothelial dysfunction (Circulation 1990; 81:491-497) and showed that endothelial dysfunction can be corrected with statin therapy (N Engl J Med 1995; 332:488-493). Currently, Dr. Ganz is making important discoveries in another field - precision medicine enabled by proteomics and machine learning. He is using modified aptamers as binding reagents to quantify the levels of thousands of proteins simultaneously in blood in order to elucidate the risk and biological basis of diseases (JAMA 2016;315:2532-2541; Circulation 2018;137:999-1010; Nature Medicine 2019;25:1851-1857). Dr. Ganz has authored over 250 peer-reviewed articles, many widely cited and published in the top tier medical journals. Numerous trainees who worked in Dr. Ganz’s laboratory have gone onto key leadership positions in academic medicine nationally and internationally. Dr. Ganz received his M.D. from Harvard Medical School, completed his residency at the Massachusetts General Hospital and cardiovascular fellowship at the Brigham and Women’s Hospital. He spent 25 years directing cardiovascular research in the Cardiac Catheterization Laboratories at the Brigham and Women’s Hospital and Harvard Medical School, prior to arriving to the University of California, San Francisco in 2008.
Education
06/1982 - Cardiology Fellowship, Brigham and Women's Hospital
06/1979 - Medical Residency, Massachusetts General Hospital
MD, 06/1976 - Medicine, Harvard Medical School
Publications
  1. Yang J, Brody EN, Murthy AC, Mehler RE, Weiss SJ, DeLisle RK, Ostroff R, Williams SA, Ganz P. Impact of Kidney Function on the Blood Proteome and on Protein Cardiovascular Risk Biomarkers in Patients With Stable Coronary Heart Disease. 2020. PMID: 32696702


  2. Ferrannini E, Murthy AC, Lee YH, Muscelli E, Weiss S, Ostroff RM, Sattar N, Williams SA, Ganz P. Mechanisms of Sodium-Glucose Cotransporter 2 Inhibition: Insights From Large-Scale Proteomics. 2020. PMID: 32527800


  3. Rich DQ, Thurston SW, Balmes JR, Bromberg PA, Arjomandi M, Hazucha MJ, Alexis NE, Ganz P, Zareba W, Thevenet-Morrison K, Koutrakis P, Frampton MW. Does Ambient Ozone or Other Pollutants Modify Effects of Controlled Ozone Exposure on Pulmonary Function? 2020. PMID: 32125874


  4. Grubbs V, Garcia F, Vittinghoff E, Jue BL, Ryder M, Lovett DH, Offenbacher S, Taylor G, Ganz P, Bibbins-Domingo K, Powe NR. Nonsurgical Periodontal Therapy in CKD: Findings of the Kidney and Periodontal Disease (KAPD) Pilot Randomized Controlled Trial. 2019. PMID: 32734226


  5. Williams SA, Kivimaki M, Langenberg C, Hingorani AD, Casas JP, Bouchard C, Jonasson C, Sarzynski MA, Shipley MJ, Alexander L, Ash J, Bauer T, Chadwick J, Datta G, DeLisle RK, Hagar Y, Hinterberg M, Ostroff R, Weiss S, Ganz P, Wareham NJ. Plasma protein patterns as comprehensive indicators of health. Volume 25 of Issue 12. 2019. PMID: 31792462


  6. Benson MD, Ngo D, Ganz P, Gerszten RE. Emerging Affinity Reagents for High Throughput Proteomics: Trust, but Verify. Volume 140 of Issue 20. 2019. PMID: 31710523


  7. Ganz T, Ganz P. William Ganz and His Legacy. Volume 170 of Issue 10. 2019. PMID: 31108522


  8. Papolos A, Fan E, Wagle RR, Foster E, Boyle AJ, Yeghiazarians Y, MacGregor JS, Grossman W, Schiller NB, Ganz P, Tison GH. Echocardiographic determination of pulmonary arterial capacitance. 2019. PMID: 30968263


  9. Wei J, Shufelt C, Oestreicher Stock E, Mills C, Dhawan S, Jacob R, Torbati T, Cook-Wiens G, Benowitz N, Jacob P, Ganz P, Bairey Merz CN, Redberg R. Vascular Aging is Accelerated in Flight Attendants with Occupational Secondhand Smoke Exposure. 2018. PMID: 30475308


  10. Conklin DJ, Schick S, Blaha MJ, Carll A, DeFilippis A, Ganz P, Hall ME, Hamburg N, O'Toole T, Reynolds L, Srivastava S, Bhatnagar A. Cardiovascular injury induced by tobacco products: assessment of risk factors and biomarkers of harm. A Tobacco Centers of Regulatory Science compilation. 2019. PMID: 30707616


  11. Tin A, Yu B, Ma J, Masushita K, Daya N, Hoogeveen RC, Ballantyne CM, Couper D, Rebholz CM, Grams ME, Alonso A, Mosley T, Heiss G, Ganz P, Selvin E, Boerwinkle E, Coresh J. Reproducibility and Variability of Protein Analytes Measured Using a Multiplexed Modified Aptamer Assay. 2019. PMID: 31639705


  12. Dubin RF, Whooley M, Pico A, Ganz P, Schiller NB, Meyer C. Proteomic analysis of heart failure hospitalization among patients with chronic kidney disease: The Heart and Soul Study. 2018. PMID: 30557359


  13. Narla V, Bhakta N, Freedman JE, Tanriverdi K, Maka K, Deeks SG, Ganz P, Hsue P. Unique Circulating MicroRNA Profiles in HIV Infection. 2018. PMID: 30204717


  14. Hsue PY, Li D, Ma Y, Ishai A, Manion M, Nahrendorf M, Ganz P, Ridker PM, Deeks SG, Tawakol A. IL-1ß Inhibition Reduces Atherosclerotic Inflammation in HIV Infection. 2018. PMID: 30497570


  15. Rich DQ, Balmes JR, Frampton MW, Zareba W, Stark P, Arjomandi M, Hazucha MJ, Costantini MG, Ganz P, Hollenbeck-Pringle D, Dagincourt N, Bromberg PA. Cardiovascular function and ozone exposure: The Multicenter Ozone Study in oldEr Subjects (MOSES). 2018. PMID: 29980042


  16. Williams SA, Murthy AC, DeLisle RK, Hyde C, Malarstig A, Ostroff R, Weiss SJ, Segal MR, Ganz P. Improving Assessment of Drug Safety Through Proteomics: Early Detection and Mechanistic Characterization of the Unforeseen Harmful Effects of Torcetrapib. Volume 137 of Issue 10. 2017. PMID: 28974520


  17. Guajardo I, Ayer A, Johnson AD, Ganz P, Mills C, Donovan C, Scherzer R, Shah SJ, Peralta CA, Dubin RF. Sex differences in vascular dysfunction and cardiovascular outcomes: The cardiac, endothelial function, and arterial stiffness in ESRD (CERES) study. 2017. PMID: 28272770


  18. Tawakol A, Ishai A, Li D, Takx RA, Hur S, Kaiser Y, Pampaloni M, Rupert A, Hsu D, Sereti I, Fromentin R, Chomont N, Ganz P, Deeks SG, Hsue PY. Association of Arterial and Lymph Node Inflammation With Distinct Inflammatory Pathways in Human Immunodeficiency Virus Infection. 2017. PMID: 27926762


  19. Huang AJ, Ganz P, Grady D, Cummings SR. In Reply. 2017. PMID: 28002350


  20. Sinha A, Ma Y, Scherzer R, Hur S, Li D, Ganz P, Deeks SG, Hsue PY. Role of T-Cell Dysfunction, Inflammation, and Coagulation in Microvascular Disease in HIV. 2016. PMID: 27998918


  21. Grubbs V, Garcia F, Jue BL, Vittinghoff E, Ryder M, Lovett D, Carrillo J, Offenbacher S, Ganz P, Bibbins-Domingo K, Powe NR. The Kidney and Periodontal Disease (KAPD) study: A pilot randomized controlled trial testing the effect of non-surgical periodontal therapy on chronic kidney disease. Volume 53. 2016. PMID: 28011387


  22. Dubin RF, Guajardo I, Ayer A, Mills C, Donovan C, Beussink L, Scherzer R, Ganz P, Shah SJ. Associations of Macro- and Microvascular Endothelial Dysfunction With Subclinical Ventricular Dysfunction in End-Stage Renal Disease. 2016. PMID: 27550915


  23. Ganz P, Heidecker B, Hveem K, Jonasson C, Kato S, Segal MR, Sterling DG, Williams SA. Development and Validation of a Protein-Based Risk Score for Cardiovascular Outcomes Among Patients With Stable Coronary Heart Disease. Volume 315 of Issue 23. 2016. PMID: 27327800


  24. Kohli P, Ganz P, Ma Y, Scherzer R, Hur S, Weigel B, Grunfeld C, Deeks S, Wasserman S, Scott R, Hsue PY. HIV and Hepatitis C-Coinfected Patients Have Lower Low-Density Lipoprotein Cholesterol Despite Higher Proprotein Convertase Subtilisin Kexin 9 (PCSK9): An Apparent "PCSK9-Lipid Paradox". Volume 5 of Issue 5. 2016. PMID: 27130349


  25. Walker RG, Poggioli T, Katsimpardi L, Buchanan SM, Oh J, Wattrus S, Heidecker B, Fong YW, Rubin LL, Ganz P, Thompson TB, Wagers AJ, Lee RT. Biochemistry and Biology of GDF11 and Myostatin: Similarities, Differences, and Questions for Future Investigation. Volume 118 of Issue 7. 2016. PMID: 27034275


  26. Huang AJ, Cummings SR, Schembri M, Vittinghoff E, Ganz P, Grady D. Continuous transdermal nitroglycerin therapy for menopausal hot flashes: a single-arm, dose-escalation trial. 2016. PMID: 26263283


  27. Parikh RV, Ma Y, Scherzer R, Heringer AS, Macgregor JS, Martin JN, Deeks SG, Ganz P, Hsue PY. Endothelin-1 Predicts Hemodynamically Assessed Pulmonary Arterial Hypertension in HIV Infection. 2016. PMID: 26752193


  28. Olson KA, Beatty AL, Heidecker B, Regan MC, Brody EN, Foreman T, Kato S, Mehler RE, Singer BS, Hveem K, Dalen H, Sterling DG, Lawn RM, Schiller NB, Williams SA, Whooley MA, Ganz P. Association of growth differentiation factor 11/8, putative anti-ageing factor, with cardiovascular outcomes and overall mortality in humans: analysis of the Heart and Soul and HUNT3 cohorts. 2015. PMID: 26294790


  29. Secemsky EA, Scherzer R, Nitta E, Wu AH, Lange DC, Deeks SG, Martin JN, Snider J, Ganz P, Hsue PY. Novel Biomarkers of Cardiac Stress, Cardiovascular Dysfunction, and Outcomes in HIV-Infected Individuals. 2015. PMID: 26164679


  30. Beatty AL, Ku IA, Bibbins-Domingo K, Christenson RH, DeFilippi CR, Ganz P, Ix JH, Lloyd-Jones D, Omland T, Sabatine MS, Schiller NB, Shlipak MG, Skali H, Takeuchi M, Vittinghoff E, Whooley MA. Traditional Risk Factors Versus Biomarkers for Prediction of Secondary Events in Patients With Stable Coronary Heart Disease: From the Heart and Soul Study. 2015. PMID: 26150476


  31. Waldo SW, Brenner DA, McCabe JM, De la Cruz M, Long B, Narla VA, Park J, Kulkarni A, Sinclair E, Chan SY, Schick SF, Malik N, Ganz P, Hsue PY. Correction: A novel minimally-invasive method to sample human endothelial cells for molecular profiling. Volume 10 of Issue 5. 2015. PMID: 25938419


  32. Matsuzawa Y, Svedlund S, Aoki T, Guddeti RR, Kwon TG, Cilluffo R, Widmer RJ, Nelson RE, Lennon RJ, Lerman LO, Gao S, Ganz P, Gan LM, Lerman A. Utility of both carotid intima-media thickness and endothelial function for cardiovascular risk stratification in patients with angina-like symptoms. Volume 190. 2015. PMID: 25918056


  33. Waldo SW, Brenner DA, McCabe JM, Dela Cruz M, Long B, Narla VA, Park J, Kulkarni A, Sinclair E, Chan SY, Schick SF, Malik N, Ganz P, Hsue PY. A novel minimally-invasive method to sample human endothelial cells for molecular profiling. Volume 10 of Issue 2. 2015. PMID: 25679506


  34. Hsue PY, Scherzer R, Grunfeld C, Imboden J, Wu Y, Del Puerto G, Nitta E, Shigenaga J, Schnell Heringer A, Ganz P, Graf J. Depletion of B-cells with rituximab improves endothelial function and reduces inflammation among individuals with rheumatoid arthritis. Volume 3 of Issue 5. 2014. PMID: 25336464


  35. Fang SC, Rosen RC, Vita JA, Ganz P, Kupelian V. Changes in erectile dysfunction over time in relation to Framingham cardiovascular risk in the Boston Area Community Health (BACH) Survey. Volume 12 of Issue 1. 2014. PMID: 25293632


  36. Gerber RE, Vita JA, Ganz P, Wager CG, Araujo AB, Rosen RC, Kupelian V. Association of peripheral microvascular dysfunction and erectile dysfunction. Volume 193 of Issue 2. 2014. PMID: 25196657


  37. Parikh RV, Scherzer R, Nitta EM, Leone A, Hur S, Mistry V, Macgregor JS, Martin JN, Deeks SG, Ganz P, Hsue PY. Increased levels of asymmetric dimethylarginine are associated with pulmonary arterial hypertension in HIV infection. 2014. PMID: 24469026


  38. Miner M, Nehra A, Jackson G, Bhasin S, Billups K, Burnett AL, Buvat J, Carson C, Cunningham G, Ganz P, Goldstein I, Guay A, Hackett G, Kloner RA, Kostis JB, LaFlamme KE, Montorsi P, Ramsey M, Rosen R, Sadovsky R, Seftel A, Shabsigh R, Vlachopoulos C, Wu F. All men with vasculogenic erectile dysfunction require a cardiovascular workup. Volume 127 of Issue 3. 2013. PMID: 24423973


  39. McCabe JM, Armstrong EJ, Ku I, Kulkarni A, Hoffmayer KS, Bhave PD, Waldo SW, Hsue P, Stein JC, Marcus GM, Kinlay S, Ganz P. Physician accuracy in interpreting potential ST-segment elevation myocardial infarction electrocardiograms. 2013. PMID: 24096575


  40. Turner TE, Waldo SW, Kulkarni A, Armstrong EJ, Hoffmayer KS, Kinlay S, Hsue P, Ganz P, McCabe JM. Long-term outcomes of patients sent emergently to the catheterization laboratory for possible primary percutaneous coronary intervention. Volume 112 of Issue 11. 2013. PMID: 24063836


  41. Waldo SW, Armstrong EJ, Kulkarni A, Hoffmayer KS, Hsue P, Ganz P, McCabe JM. Clinical characteristics and reperfusion times among patients with an isolated posterior myocardial infarction. Volume 25 of Issue 8. 2013. PMID: 23913600


  42. Brenner DA, Dela Cruz M, Thomas K, McCabe JM, Ganz P, Hsue PY, Waldo SW. Emergency medical service utilization and door-to-balloon time for HIV-infected individuals with ST-elevation myocardial infarction. Volume 168 of Issue 5. 2013. PMID: 23871355


  43. Ganz P, Hsue PY. Endothelial dysfunction in coronary heart disease is more than a systemic process. Volume 34 of Issue 27. 2013. PMID: 23756335


  44. Parikh RV, Scherzer R, Grunfeld C, Nitta EM, Leone A, Martin JN, Deeks SG, Ganz P, Hsue PY. Elevated levels of asymmetric dimethylarginine are associated with lower CD4+ count and higher viral load in HIV-infected individuals. Volume 229 of Issue 1. 2013. PMID: 23711612


  45. Waldo SW, Armstrong EJ, Kulkarni A, Hoffmayer K, Kinlay S, Hsue P, Ganz P, McCabe JM. Comparison of clinical characteristics and outcomes of cardiac arrest survivors having versus not having coronary angiography. Volume 111 of Issue 9. 2013. PMID: 23391104


  46. Zamani P, Schwartz GG, Olsson AG, Rifai N, Bao W, Libby P, Ganz P, Kinlay S. Inflammatory biomarkers, death, and recurrent nonfatal coronary events after an acute coronary syndrome in the MIRACL study. Volume 2 of Issue 1. 2013. PMID: 23525424


  47. Flammer AJ, Anderson T, Celermajer DS, Creager MA, Deanfield J, Ganz P, Hamburg NM, Lüscher TF, Shechter M, Taddei S, Vita JA, Lerman A. The assessment of endothelial function: from research into clinical practice. Volume 126 of Issue 6. 2012. PMID: 22869857


  48. Armstrong EJ, Kulkarni AR, Bhave PD, Hoffmayer KS, Macgregor JS, Stein JC, Kinlay S, Ganz P, McCabe JM. Electrocardiographic criteria for ST-elevation myocardial infarction in patients with left ventricular hypertrophy. 2012. PMID: 22738872


  49. McCabe JM, Armstrong EJ, Kulkarni A, Hoffmayer KS, Bhave PD, Garg S, Patel A, MacGregor JS, Hsue P, Stein JC, Kinlay S, Ganz P. Prevalence and factors associated with false-positive ST-segment elevation myocardial infarction diagnoses at primary percutaneous coronary intervention–capable centers: a report from the Activate-SF registry. 2012. PMID: 22566489


  50. Miner M, Seftel AD, Nehra A, Ganz P, Kloner RA, Montorsi P, Vlachopoulos C, Ramsey M, Sigman M, Tilkemeier P, Jackson G. Prognostic utility of erectile dysfunction for cardiovascular disease in younger men and those with diabetes. Volume 164 of Issue 1. 2012. PMID: 22795278


  51. Ho JE, Scherzer R, Hecht FM, Maka K, Selby V, Martin JN, Ganz P, Deeks SG, Hsue PY. The association of CD4+ T-cell counts and cardiovascular risk in treated HIV disease. 2012. PMID: 22382147


  52. Frey PF, Ganz P, Hsue PY, Benowitz NL, Glantz SA, Balmes JR, Schick SF. The exposure-dependent effects of aged secondhand smoke on endothelial function. Volume 59 of Issue 21. 2012. PMID: 22595411


  53. Hsue PY, Scherzer R, Hunt PW, Schnell A, Bolger AF, Kalapus SC, Maka K, Martin JN, Ganz P, Deeks SG. Carotid Intima-Media Thickness Progression in HIV-Infected Adults Occurs Preferentially at the Carotid Bifurcation and Is Predicted by Inflammation. Volume 1 of Issue 2. 2012. PMID: 23130122


  54. Armstrong EJ, Kulkarni AR, Hoffmayer KS, Bhave PD, MacGregor JS, Hsue P, Stein JC, Kinlay S, Ganz P, McCabe JM. Delaying primary percutaneous coronary intervention for computed tomographic scans in the emergency department. 2012. PMID: 22534052


  55. Zamani P, Ganz P, Libby P, Sutradhar SC, Rifai N, Nicholls SJ, Nissen SE, Kinlay S. Relationship of antihypertensive treatment to plasma markers of vascular inflammation and remodeling in the Comparison of Amlodipine versus Enalapril to Limit Occurrences of Thrombosis study. Volume 163 of Issue 4. 2012. PMID: 22520542


  56. Hong TT, Cogswell R, James CA, Kang G, Pullinger CR, Malloy MJ, Kane JP, Wojciak J, Calkins H, Scheinman MM, Tseng ZH, Ganz P, De Marco T, Judge DP, Shaw RM. Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy. Volume 9 of Issue 6. 2012. PMID: 22300662


  57. Hsue PY, Ordovas K, Lee T, Reddy G, Gotway M, Schnell A, Ho JE, Selby V, Madden E, Martin JN, Deeks SG, Ganz P, Waters DD. Carotid intima-media thickness among human immunodeficiency virus-infected patients without coronary calcium. 2011. PMID: 22169125


  58. Secemsky EA, Lange D, Ho JE, Brayton K, Ganz PA, Farr G, Macgregor JS, Hsue PY. Improvement in revascularization time after creation of a coronary catheterization laboratory at a public hospital. 2011. PMID: 22123753


  59. Bhave PD, Hoffmayer KS, Armstrong EJ, Garg S, Patel A, Macgregor JS, Stein JC, Kinlay S, Ganz P, McCabe JM. Predictors of depressed left ventricular function in patients presenting with ST-elevation myocardial infarction. 2011. PMID: 22078964


  60. Di Carli MF, Charytan D, McMahon GT, Ganz P, Dorbala S, Schelbert HR. Coronary circulatory function in patients with the metabolic syndrome. Volume 52 of Issue 9. 2011. PMID: 21849399


  61. Morishige K, Kacher DF, Libby P, Josephson L, Ganz P, Weissleder R, Aikawa M. High-resolution magnetic resonance imaging enhanced with superparamagnetic nanoparticles measures macrophage burden in atherosclerosis. Volume 122 of Issue 17. 2010. PMID: 20937980


  62. Friedewald VE, Ganz P, Kremer JM, Mease PJ, O'Dell JR, Pearson TA, Ram CV, Ridker PM, Salmon JE, Roberts WC. AJC editor's consensus: rheumatoid arthritis and atherosclerotic cardiovascular disease. Volume 106 of Issue 3. 2010. PMID: 20643261


  63. Edelbauer M, Datta D, Vos IH, Basu A, Stack MP, Reinders ME, Sho M, Calzadilla K, Ganz P, Briscoe DM. Effect of vascular endothelial growth factor and its receptor KDR on the transendothelial migration and local trafficking of human T cells in vitro and in vivo. Volume 116 of Issue 11. 2010. PMID: 20538805


  64. Araujo AB, Hall SA, Ganz P, Chiu GR, Rosen RC, Kupelian V, Travison TG, McKinlay JB. Does erectile dysfunction contribute to cardiovascular disease risk prediction beyond the Framingham risk score? Volume 55 of Issue 4. 2010. PMID: 20117441


  65. Ganz P, Hsue PY. Assessment of structural disease in the coronary microvasculature. Volume 120 of Issue 16. 2009. PMID: 19805646


  66. Hsue PY, Hunt PW, Wu Y, Schnell A, Ho JE, Hatano H, Xie Y, Martin JN, Ganz P, Deeks SG. Association of abacavir and impaired endothelial function in treated and suppressed HIV-infected patients. Volume 23 of Issue 15. 2009. PMID: 19542863


  67. Beltrame JF, Ganz P. Evaluating patients with persistent chest pain and no obstructive coronary artery disease. Volume 302 of Issue 6. 2009. PMID: 19671898


  68. Larose E, Behrendt D, Kinlay S, Selwyn AP, Ganz P, Fang JC. Endothelin-1 is a key mediator of coronary vasoconstriction in patients with transplant coronary arteriosclerosis. Volume 2 of Issue 5. 2009. PMID: 19808370


  69. Araujo AB, Travison TG, Ganz P, Chiu GR, Kupelian V, Rosen RC, Hall SA, McKinlay JB. Erectile dysfunction and mortality. Volume 6 of Issue 9. 2009. PMID: 19538544


  70. Ganz P, Ho JE, Hsue PY. Structural and functional manifestations of human atherosclerosis: do they run in parallel? Volume 30 of Issue 13. 2009. PMID: 19502231


  71. Hsue PY, Hunt PW, Schnell A, Kalapus SC, Hoh R, Ganz P, Martin JN, Deeks SG. Role of viral replication, antiretroviral therapy, and immunodeficiency in HIV-associated atherosclerosis. Volume 23 of Issue 9. 2009. PMID: 19390417


  72. Ku IA, Imboden JB, Hsue PY, Ganz P. Rheumatoid arthritis: model of systemic inflammation driving atherosclerosis. 2009. PMID: 19430165


  73. Kinlay S, Schwartz GG, Olsson AG, Rifai N, Bao W, Libby P, Ganz P. Endogenous tissue plasminogen activator and risk of recurrent cardiac events after an acute coronary syndrome in the MIRACL study. Volume 206 of Issue 2. 2009. PMID: 19394618


  74. Rawlings R, Nohria A, Liu PY, Donnelly J, Creager MA, Ganz P, Selwyn A, Liao JK. Comparison of effects of rosuvastatin (10 mg) versus atorvastatin (40 mg) on rho kinase activity in caucasian men with a previous atherosclerotic event. Volume 103 of Issue 4. 2008. PMID: 19195498


  75. Nohria A, Prsic A, Liu PY, Okamoto R, Creager MA, Selwyn A, Liao JK, Ganz P. Statins inhibit Rho kinase activity in patients with atherosclerosis. Volume 205 of Issue 2. 2008. PMID: 19167712


  76. Serruys PW, García-García HM, Buszman P, Erne P, Verheye S, Aschermann M, Duckers H, Bleie O, Dudek D, Bøtker HE, von Birgelen C, D'Amico D, Hutchinson T, Zambanini A, Mastik F, van Es GA, van der Steen AF, Vince DG, Ganz P, Hamm CW, Wijns W, Zalewski A. Effects of the direct lipoprotein-associated phospholipase A(2) inhibitor darapladib on human coronary atherosclerotic plaque. Volume 118 of Issue 11. 2008. PMID: 18765397


  77. Kinlay S, Schwartz GG, Olsson AG, Rifai N, Szarek M, Waters DD, Libby P, Ganz P. Inflammation, statin therapy, and risk of stroke after an acute coronary syndrome in the MIRACL study. Volume 28 of Issue 1. 2007. PMID: 17991875


  78. Larose E, Kinlay S, Selwyn AP, Yeghiazarians Y, Yucel EK, Kacher DF, Libby P, Ganz P. Improved characterization of atherosclerotic plaques by gadolinium contrast during intravascular magnetic resonance imaging of human arteries. 2007. PMID: 17391676


  79. Larose E, Ganz P, Reynolds HG, Dorbala S, Di Carli MF, Brown KA, Kwong RY. Right ventricular dysfunction assessed by cardiovascular magnetic resonance imaging predicts poor prognosis late after myocardial infarction. Volume 49 of Issue 8. 2007. PMID: 17320743


  80. Nohria A, Grunert ME, Rikitake Y, Noma K, Prsic A, Ganz P, Liao JK, Creager MA. Rho kinase inhibition improves endothelial function in human subjects with coronary artery disease. Volume 99 of Issue 12. 2006. PMID: 17095725


  81. Nohria A, Gerhard-Herman M, Creager MA, Hurley S, Mitra D, Ganz P. Role of nitric oxide in the regulation of digital pulse volume amplitude in humans. Volume 101 of Issue 2. 2006. PMID: 16614356


  82. Behrendt D, Beltrame J, Hikiti H, Wainstein M, Kinlay S, Selwyn AP, Ganz P, Fang JC. Impact of coronary endothelial function on the progression of cardiac transplant-associated arteriosclerosis: effect of anti-oxidant vitamins C and E. Volume 25 of Issue 4. 2006. PMID: 16563973


  83. Nissen SE, Tuzcu EM, Brewer HB, Sipahi I, Nicholls SJ, Ganz P, Schoenhagen P, Waters DD, Pepine CJ, Crowe TD, Davidson MH, Deanfield JE, Wisniewski LM, Hanyok JJ, Kassalow LM. Effect of ACAT inhibition on the progression of coronary atherosclerosis. Volume 354 of Issue 12. 2006. PMID: 16554527


  84. Kostis JB, Jackson G, Rosen R, Barrett-Connor E, Billups K, Burnett AL, Carson C, Cheitlin M, Debusk R, Fonseca V, Ganz P, Goldstein I, Guay A, Hatzichristou D, Hollander JE, Hutter A, Katz S, Kloner RA, Mittleman M, Montorsi F, Montorsi P, Nehra A, Sadovsky R, Shabsigh R. Sexual dysfunction and cardiac risk (the Second Princeton Consensus Conference). Volume 96 of Issue 12B. 2005. PMID: 16387575


  85. Larose E, Yeghiazarians Y, Libby P, Yucel EK, Aikawa M, Kacher DF, Aikawa E, Kinlay S, Schoen FJ, Selwyn AP, Ganz P. Characterization of human atherosclerotic plaques by intravascular magnetic resonance imaging. 2005. PMID: 16203910


  86. Kostis JB, Jackson G, Rosen R, Barrett-Connor E, Billups K, Burnett AL, Carson C, Cheitlin M, Debusk R, Fonseca V, Ganz P, Goldstein I, Guay A, Hatzichristou D, Hollander JE, Hutter A, Katz S, Kloner RA, Mittleman M, Montorsi F, Montorsi P, Nehra A, Sadovsky R, Shabsigh R. Sexual dysfunction and cardiac risk (the Second Princeton Consensus Conference). Volume 96 of Issue 2. 2005. PMID: 16018863


  87. Olsson AG, Schwartz GG, Szarek M, Sasiela WJ, Ezekowitz MD, Ganz P, Oliver MF, Waters D, Zeiher A. High-density lipoprotein, but not low-density lipoprotein cholesterol levels influence short-term prognosis after acute coronary syndrome: results from the MIRACL trial. Volume 26 of Issue 9. 2005. PMID: 15764620


  88. Nissen SE, Tuzcu EM, Schoenhagen P, Crowe T, Sasiela WJ, Tsai J, Orazem J, Magorien RD, O'Shaughnessy C, Ganz P. Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease. Volume 352 of Issue 1. 2005. PMID: 15635110


  89. Larose E, Ganz P. Statins and endothelial dysfunction. Volume 4 of Issue 4. 2004. PMID: 15861315


  90. Hamburg NM, Charbonneau F, Gerhard-Herman M, Ganz P, Creager MA. Comparison of endothelial function in young men and women with a family history of premature coronary artery disease. Volume 94 of Issue 6. 2004. PMID: 15374789


  91. Davignon J, Ganz P. Role of endothelial dysfunction in atherosclerosis. Volume 109 of Issue 23 Suppl 1. 2004. PMID: 15198963


  92. Nissen SE, Tuzcu EM, Schoenhagen P, Brown BG, Ganz P, Vogel RA, Crowe T, Howard G, Cooper CJ, Brodie B, Grines CL, DeMaria AN. Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trial. Volume 291 of Issue 9. 2004. PMID: 14996776


  93. Kinlay S, Behrendt D, Fang JC, Delagrange D, Morrow J, Witztum JL, Rifai N, Selwyn AP, Creager MA, Ganz P. Long-term effect of combined vitamins E and C on coronary and peripheral endothelial function. Volume 43 of Issue 4. 2004. PMID: 14975474


  94. Kinlay S, Ganz P. Early statin therapy in acute coronary syndromes. Volume 3 of Issue 4. 2003. PMID: 15199449


  95. Schwartz GG, Ganz P, Waters D, Arikian S. Pharmacoeconomic evaluation of the effects of atorvastatin on early recurrent ischemic events in acute coronary syndromes. Volume 92 of Issue 9. 2003. PMID: 14583367


  96. Ganz P, Vita JA. Testing endothelial vasomotor function: nitric oxide, a multipotent molecule. Volume 108 of Issue 17. 2003. PMID: 14581383


  97. Kinlay S, Schwartz GG, Olsson AG, Rifai N, Leslie SJ, Sasiela WJ, Szarek M, Libby P, Ganz P. High-dose atorvastatin enhances the decline in inflammatory markers in patients with acute coronary syndromes in the MIRACL study. Volume 108 of Issue 13. 2003. PMID: 12975259


  98. Reinders ME, Fang JC, Wong W, Ganz P, Briscoe DM. Expression patterns of vascular endothelial growth factor in human cardiac allografts: association with rejection. Volume 76 of Issue 1. 2003. PMID: 12865814


  99. Nohria A, Garrett L, Johnson W, Kinlay S, Ganz P, Creager MA. Endothelin-1 and vascular tone in subjects with atherogenic risk factors. Volume 42 of Issue 1. 2003. PMID: 12756218


  100. Schönbeck U, Gerdes N, Varo N, Reynolds RS, Horton DB, Bavendiek U, Robbie L, Ganz P, Kinlay S, Libby P. Oxidized low-density lipoprotein augments and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors limit CD40 and CD40L expression in human vascular cells. Volume 106 of Issue 23. 2002. PMID: 12460867


  101. Fang JC, Kinlay S, Behrendt D, Hikita H, Witztum JL, Selwyn AP, Ganz P. Circulating autoantibodies to oxidized LDL correlate with impaired coronary endothelial function after cardiac transplantation. Volume 22 of Issue 12. 2002. PMID: 12482832


  102. Behrendt D, Ganz P. Endothelial function. From vascular biology to clinical applications. Volume 90 of Issue 10C. 2002. PMID: 12459427


  103. Waters DD, Schwartz GG, Olsson AG, Zeiher A, Oliver MF, Ganz P, Ezekowitz M, Chaitman BR, Leslie SJ, Stern T. Effects of atorvastatin on stroke in patients with unstable angina or non-Q-wave myocardial infarction: a Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) substudy. Volume 106 of Issue 13. 2002. PMID: 12270864


  104. Johnson W, Nohria A, Garrett L, Fang JC, Igo J, Katai M, Ganz P, Creager MA. Contribution of endothelin to pulmonary vascular tone under normoxic and hypoxic conditions. Volume 283 of Issue 2. 2002. PMID: 12124203


  105. Kinlay S, Grewal J, Manuelin D, Fang JC, Selwyn AP, Bittl JA, Ganz P. Coronary flow velocity and disturbed flow predict adverse clinical outcome after coronary angioplasty. Volume 22 of Issue 8. 2002. PMID: 12171797


  106. Ganz P. Vasomotor and vascular effects of hormone replacement therapy. Volume 90 of Issue 1A. 2002. PMID: 12106634


  107. Fang JC, Kinlay S, Beltrame J, Hikiti H, Wainstein M, Behrendt D, Suh J, Frei B, Mudge GH, Selwyn AP, Ganz P. Effect of vitamins C and E on progression of transplant-associated arteriosclerosis: a randomised trial. Volume 359 of Issue 9312. 2002. PMID: 11943259