Priscilla Hsue, MD

Professor

Professional Experience: Dr. Hsue trained in Internal Medicine in the Molecular Medicine Training Program at UC San Francisco and in Cardiovascular Medicine at UC San Francisco. She served as Chief Cardiology Fellow during this time. She has been on the faculty in the Department of Medicine at San Francisco General Hospital since 2002. She started the HIV Cardiology Clinic since March 2004 at the Positive Health Program at Ward 86, which is one of the first subspeciality clinics of its kind in the nation.

Research Interests:
- Cardiovascular complications of cocaine including aortic dissection, myocardial infarction, and cardiac arrest
- Pathogenesis of atherosclerosis in HIV-infected patients treated with antiretroviral therapy
- Clinical features and outcomes of acute coronary syndromes in HIV-infected patients
- Incidence and mechanisms of pulmonary hypertension in HIV-infected patients
- Dyslipidemia in HIV-infected patients
Education
Cert, 2006 - Medicine (Advance Training in Clinical Research), University of California, San Francisco
M.D., 1996 - Medicine, University of California, San Francisco
Clinical Fellowship, - School of Medicine, University of California, San Francisco
Residency, - School of Medicine, University of California, San Francisco
Publications
  1. Tardif JC, Bouabdallaoui N, L'Allier PL, Gaudet D, Shah B, Pillinger MH, Lopez-Sendon J, da Luz P, Verret L, Audet S, Dupuis J, Denault A, Pelletier M, Tessier PA, Samson S, Fortin D, Tardif JD, Busseuil D, Goulet E, Lacoste C, Dubois A, Joshi AY, Waters DD, Hsue P, Lepor NE, Lesage F, Sainturet N, Roy-Clavel E, Bassevitch Z, Orfanos A, Stamatescu G, Grégoire JC, Busque L, Lavallée C, Hétu PO, Paquette JS, Deftereos SG, Levesque S, Cossette M, Nozza A, Chabot-Blanchet M, Dubé MP, Guertin MC, Boivin G, COLCORONA Investigators. Colchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded, adaptive, placebo-controlled, multicentre trial. 2021. PMID: 34051877


  2. Krishnamachary B, Mahajan A, Kumar A, Agarwal S, Mohan A, Chen L, Hsue P, Chalise P, Morris A, Dhillon NK. Extracellular vesicle TGF-ß1 is linked to cardiopulmonary dysfunction in HIV. 2021. PMID: 34014809


  3. Peluso MJ, Kelly JD, Lu S, Goldberg SA, Davidson MC, Mathur S, Durstenfeld MS, Spinelli MA, Hoh R, Tai V, Fehrman EA, Torres L, Hernandez Y, Williams MC, Arreguin MI, Bautista JA, Ngo LH, Deswal M, Munter SE, Martinez EO, Anglin KA, Romero MD, Tavs J, Rugart PR, Chen JY, Sans HM, Murray VW, Ellis PK, Donohue KC, Massachi JA, Weiss JO, Mehdi I, Pineda-Ramirez J, Tang AF, Wenger M, Assenzio M, Yuan Y, Krone M, Rutishauser RL, Rodriguez-Barraquer I, Greenhouse B, Sauceda JA, Gandhi M, Hsue PY, Henrich TJ, Deeks SG, Martin JN. Rapid implementation of a cohort for the study of post-acute sequelae of SARS-CoV-2 infection/COVID-19. 2021. PMID: 33758895


  4. Van Dyke TE, Kholy KE, Ishai A, Takx RAP, Mezue K, Abohashem SM, Ali A, Yuan N, Hsue P, Osborne MT, Tawakol A. Inflammation of the periodontium associates with risk of future cardiovascular events. 2021. PMID: 33512014


  5. Zhang L, Abohashem S, Osborne MT, Naddaf N, Park R, Moore K, Patrich T, Deeks SG, Hsue PY, Tawakol AA. Lower Socioeconomic Status Associates with Greater Systemic and Arterial Inflammation in HIV. 2021. PMID: 33492022


  6. Gingrich D, Deitchman AN, Kantor A, Huang L, Stein JH, Currier JS, Hsue PY, Ribaudo HJ, Aweeka FT. Methotrexate Decreases Tenofovir Exposure in Antiretroviral-Suppressed Individuals Living With HIV. 2020. PMID: 33177476


  7. Parks MM, Secemsky EA, Yeh RW, Shen C, Choi E, Kazi DS, Hsue PY. Longitudinal Management and Outcomes of Acute Coronary Syndrome in Persons Living with HIV Infection. 2020. PMID: 33226071


  8. Chow FC, Ma Y, Manion M, Rupert A, Lambert-Messerlian G, Bushnell CD, Cedars MI, Sereti I, Sorond FA, Hsue PY, Tien PC. Factors associated with worse cerebrovascular function in aging women with and at risk for HIV. 2020. PMID: 33229895


  9. McLaughlin MM, Ma Y, Scherzer R, Rahalkar S, Martin JN, Mills C, Milush J, Deeks SG, Hsue PY. Association of Viral Persistence and Atherosclerosis in Adults With Treated HIV Infection. 2020. PMID: 33119103


  10. Riley ED, Vittinghoff E, Wu AHB, Coffin PO, Hsue PY, Kazi DS, Wade A, Braun C, Lynch KL. Impact of polysubstance use on high-sensitivity cardiac troponin I over time in homeless and unstably housed women. 2020. PMID: 32919207


  11. Martin T, Gianella S, Franklin D, Hsue P, Smith DM. Methamphetamine and cardiac disease among people with HIV infection. 2020. PMID: 32741089


  12. Almodovar S, Wade BE, Porter KM, Smith JM, Lopez-Astacio RA, Bijli K, Kang BY, Cribbs SK, Guidot DM, Molehin D, McNair BK, Pumarejo-Gomez L, Perez Hernandez J, Salazar EA, Martinez EG, Huang L, Kessing CF, Suarez-Martinez EB, Pruitt K, Hsue PY, Tyor WR, Flores SC, Sutliff RL. HIV X4 Variants Increase Arachidonate 5-Lipoxygenase in the Pulmonary Microenvironment and are associated with Pulmonary Arterial Hypertension. 2020. PMID: 32678115


  13. Phan BAP, Ma Y, Scherzer R, Deeks SG, Hsue PY. Association between statin use, atherosclerosis, and mortality in HIV-infected adults. 2020. PMID: 32353062


  14. So-Armah K, Benjamin LA, Bloomfield GS, Feinstein MJ, Hsue P, Njuguna B, Freiberg MS. HIV and cardiovascular disease. Volume 7 of Issue 4. 2020. PMID: 32243826


  15. Hsu DC, Ma YF, Narwan A, Rahalkar S, Rupert A, Scherzer R, Mills C, Deeks S, Sereti I, Hsue PY. Plasma tissue factor and immune activation are associated with carotid intima-media thickness progression in treated HIV infection. 2019. PMID: 31634197


  16. Currier JS, Hsue PY. The Role of Inflammation in HIV-Associated Atherosclerosis-One Size May Not Fit All. Volume 221 of Issue 4. 2020. PMID: 31077267


  17. Titanji B, Gavegnano C, Hsue P, Schinazi R, Marconi VC. Targeting Inflammation to Reduce Atherosclerotic Cardiovascular Risk in People With HIV Infection. Volume 9 of Issue 3. 2020. PMID: 31973607


  18. Greene M, Myers J, Tan JY, Blat C, O'Hollaren A, Quintanilla F, Hsue P, Shiels M, Hicks ML, Olson B, Grochowski J, Oskarsson J, Havlir D, Gandhi M. The Golden Compass Program: Overview of the Initial Implementation of a Comprehensive Program for Older Adults Living with HIV. 2020. PMID: 32715875


  19. Yuan N, Scherzer R, Tanriverdi K, Martin J, Rahalkar S, Hsue P. MicroRNA biomarkers associated with type 1 myocardial infarction in HIV-positive individuals. Volume 33 of Issue 15. 2019. PMID: 31764100


  20. Huhn GD, Shamblaw DJ, Baril JG, Hsue PY, Mills BL, Nguyen-Cleary T, McCallister S, Das M. Atherosclerotic Cardiovascular Disease Risk Profile of Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate. Volume 7 of Issue 1. 2019. PMID: 31950070


  21. Butler J, Greene SJ, Shah SH, Shah SJ, Anstrom KJ, Kim RJ, Kalogeropoulos AP, Velazquez EJ, Hernandez AF, Desvigne-Nickens P, Scherzer R, Hsue PY, Braunwald E. Diastolic Dysfunction in Patients With Human Immunodeficiency Virus Receiving Antiretroviral Therapy: Results From the CHART Study. Volume 26 of Issue 5. 2019. PMID: 31682908


  22. Sardana M, Hsue PY, Tseng ZH, Vittinghoff E, Nah G, Dewland TA, Marcus GM. Human Immunodeficiency Virus Infection and Incident Atrial Fibrillation. 2019. PMID: 31514955


  23. Henrich TJ, Hsue PY, VanBrocklin H. Seeing Is Believing: Nuclear Imaging of HIV Persistence. 2019. PMID: 31572355


  24. Feinstein MJ, Nance RM, Delaney JAC, Heckbert SR, Budoff MJ, Drozd DR, Burkholder GA, Willig JH, Mugavero MJ, Mathews WC, Moore RD, Eron JJ, Napravnik S, Hunt PW, Geng E, Hsue P, Peter I, Lober WB, Crothers K, Grunfeld C, Saag MS, Kitahata MM, Lloyd-Jones DM, Crane HM. Mortality following myocardial infarction among HIV-infected persons: the Center for AIDS Research Network Of Integrated Clinical Systems (CNICS). 2019. PMID: 31362721


  25. Ishai A, Osborne MT, El Kholy K, Takx RAP, Ali A, Yuan N, Hsue P, Van Dyke TE, Tawakol A. Periodontal Disease Associates With Arterial Inflammation Via Potentiation of a Hematopoietic-Arterial Axis. Volume 12 of Issue 11 Pt 1. 2019. PMID: 31326471


  26. Hsue PY, Waters DD. HIV infection and coronary heart disease: mechanisms and management. Volume 16 of Issue 12. 2019. PMID: 31182833


  27. Feinstein MJ, Hsue PY, Benjamin LA, Bloomfield GS, Currier JS, Freiberg MS, Grinspoon SK, Levin J, Longenecker CT, Post WS. Characteristics, Prevention, and Management of Cardiovascular Disease in People Living With HIV: A Scientific Statement From the American Heart Association. Volume 140 of Issue 2. 2019. PMID: 31154814


  28. Hsue PY, Ribaudo HJ, Deeks SG, Bell T, Ridker PM, Fichtenbaum C, Daar ES, Havlir D, Yeh E, Tawakol A, Lederman M, Currier JS, Stein JH. Safety and Impact of Low-Dose Methotrexate on Endothelial Function and Inflammation in Individuals with Treated Human Immunodeficiency Virus: AIDS Clinical Trials Group Study A5314. 2018. PMID: 30219823


  29. Sinha A, Ma Y, Scherzer R, Rahalkar S, Neilan BD, Crane H, Drozd D, Martin J, Deeks SG, Hunt P, Hsue PY. Carnitine Is Associated With Atherosclerotic Risk and Myocardial Infarction in HIV -Infected Adults. 2019. PMID: 31030595


  30. Hsue PY. Mechanisms of Cardiovascular Disease in the Setting of HIV Infection. Volume 35 of Issue 3. 2018. PMID: 30825947


  31. Narla V, Bhakta N, Freedman JE, Tanriverdi K, Maka K, Deeks SG, Ganz P, Hsue P. Unique Circulating MicroRNA Profiles in HIV Infection. 2018. PMID: 30204717


  32. Waters DD, Hsue PY. Introduction to Cardiovascular Issues in HIV. Volume 35 of Issue 3. 2018. PMID: 30825945


  33. Hsue PY, Li D, Ma Y, Ishai A, Manion M, Nahrendorf M, Ganz P, Ridker PM, Deeks SG, Tawakol A. IL-1ß Inhibition Reduces Atherosclerotic Inflammation in HIV Infection. 2018. PMID: 30497570


  34. Stein JH, Yeh E, Weber JM, Korcarz C, Ridker PM, Tawakol A, Hsue PY, Currier JS, Ribaudo H, Mitchell CKC. Brachial Artery Echogenicity and Grayscale Texture Changes in HIV-Infected Individuals Receiving Low-Dose Methotrexate. Volume 38 of Issue 12. 2018. PMID: 30571173


  35. Waters DD, Hsue PY. Lipid Abnormalities in Persons Living With HIV Infection. Volume 35 of Issue 3. 2018. PMID: 30704819


  36. Feinstein MJ, Steverson AB, Ning H, Pawlowski AE, Schneider D, Ahmad FS, Sanders JM, Sinha A, Nance RM, Achenbach CJ, Christopher Delaney JA, Heckbert SR, Shah SJ, Hanna DB, Hsue PY, Bloomfield GS, Longenecker CT, Crane HM, Lloyd-Jones DM. Adjudicated Heart Failure in HIV-Infected and Uninfected Men and Women. Volume 7 of Issue 21. 2018. PMID: 30571387


  37. Libby P, Loscalzo J, Ridker PM, Farkouh ME, Hsue PY, Fuster V, Hasan AA, Amar S. Inflammation, Immunity, and Infection in Atherothrombosis: JACC Review Topic of the Week. Volume 72 of Issue 17. 2018. PMID: 30336831


  38. Hsue PY, Waters DD. Time to Recognize HIV Infection as a Major Cardiovascular Risk Factor. Volume 138 of Issue 11. 2018. PMID: 30354392


  39. Nance R, Crane H, Ritchings C, Rosenblatt LC, Budoff M, Heckbert SR, Drozd D, Matthews WC, Geng E, Hunt PW, Feinstein MJ, Moore R, Hseu P, Eron JJ, Burkholder GA, Rodriguez B, Mugavero MJ, Saag M, Kitahata MM, Delaney JA. Differentiation of Type 1 and Type 2 Myocardial Infarctions among HIV-infected patients requires adjudication due to overlap in risk factors. 2018. PMID: 29984593


  40. Scherzer R, Shah SJ, Secemsky E, Butler J, Grunfeld C, Shlipak MG, Hsue PY. Association of Biomarker Clusters With Cardiac Phenotypes and Mortality in Patients With HIV Infection. Volume 11 of Issue 4. 2018. PMID: 29615435


  41. Brittain EL, Duncan MS, Chang J, Patterson OV, DuVall SL, Brandt CA, So-Armah KA, Goetz M, Akgun K, Crothers K, Zola C, Kim J, Gibert C, Pisani M, Morris A, Hsue P, Tindle HA, Justice A, Freiberg M. Increased Echocardiographic Pulmonary Pressure in HIV-infected and -uninfected Individuals in the Veterans Aging Cohort Study. Volume 197 of Issue 7. 2018. PMID: 29131651


  42. Butler J, Kalogeropoulos AP, Anstrom KJ, Hsue PY, Kim RJ, Scherzer R, Shah SJ, Shah SH, Velazquez EJ, Hernandez AF, Desvigne-Nickens P, Braunwald E. Diastolic Dysfunction in Individuals With Human Immunodeficiency Virus Infection: Literature Review, Rationale and Design of the Characterizing Heart Function on Antiretroviral Therapy (CHART) Study. Volume 24 of Issue 4. 2018. PMID: 29482027


  43. Gallant J, Hsue PY, Shreay S, Meyer N. Comorbidities Among US Patients With Prevalent HIV Infection-A Trend Analysis. Volume 216 of Issue 12. 2017. PMID: 29253205


  44. Hsue PY, Waters DD. Heart failure in persons living with HIV infection. Volume 12 of Issue 6. 2017. PMID: 28863015


  45. Smit M, Cassidy R, Cozzi-Lepri A, Quiros-Roldan E, Girardi E, Mammone A, Antinori A, Saracino A, Bai F, Rusconi S, Magnani G, Castelli F, Hsue P, d'Arminio Monforte A, Hallett TB. Projections of non-communicable disease and health care costs among HIV-positive persons in Italy and the U.S.A.: A modelling study. Volume 12 of Issue 10. 2017. PMID: 29059202


  46. Gallant J, Hsue P, Budd D, Meyer N. Healthcare utilization and direct costs of non-infectious comorbidities in HIV-infected patients in the USA. Volume 34 of Issue 1. 2017. PMID: 28933204


  47. Chau KH, Scherzer R, Grunfeld C, Hsue PY, Shlipak MG. CHA2DS2-VASc Score, Warfarin Use, and Risk for Thromboembolic Events Among HIV-Infected Persons With Atrial Fibrillation. Volume 76 of Issue 1. 2017. PMID: 28797024


  48. Phan BAP, Weigel B, Ma Y, Scherzer R, Li D, Hur S, Kalapus SC, Deeks S, Hsue P. Utility of 2013 American College of Cardiology/American Heart Association Cholesterol Guidelines in HIV-Infected Adults With Carotid Atherosclerosis. 2017. PMID: 28674084


  49. Waters DD, Hsue PY. PCSK9 Inhibition to Reduce Cardiovascular Risk: Tempering Expectations. Volume 120 of Issue 10. 2017. PMID: 28495986


  50. Chen R, Scherzer R, Hsue PY, Jotwani V, Estrella MM, Horberg MA, Grunfeld C, Shlipak MG. Association of Tenofovir Use With Risk of Incident Heart Failure in HIV-Infected Patients. Volume 6 of Issue 4. 2017. PMID: 28438737


  51. Crane HM, Paramsothy P, Drozd DR, Nance RM, Delaney JA, Heckbert SR, Budoff MJ, Burkholder GA, Willig JH, Mugavero MJ, Mathews WC, Crane PK, Moore RD, Eron JJ, Napravnik S, Hunt PW, Geng E, Hsue P, Rodriguez C, Peter I, Barnes GS, McReynolds J, Lober WB, Crothers K, Feinstein MJ, Grunfeld C, Saag MS, Kitahata MM. Types of Myocardial Infarction Among Human Immunodeficiency Virus-Infected Individuals in the United States. Volume 2 of Issue 3. 2017. PMID: 28052152


  52. Tawakol A, Ishai A, Li D, Takx RA, Hur S, Kaiser Y, Pampaloni M, Rupert A, Hsu D, Sereti I, Fromentin R, Chomont N, Ganz P, Deeks SG, Hsue PY. Association of Arterial and Lymph Node Inflammation With Distinct Inflammatory Pathways in Human Immunodeficiency Virus Infection. 2017. PMID: 27926762


  53. Riley ED, Hsue PY, Vittinghoff E, Wu AH, Coffin PO, Moore PK, Lynch KL. Higher prevalence of detectable troponin I among cocaine-users without known cardiovascular disease. 2017. PMID: 28157591


  54. Sinha A, Ma Y, Scherzer R, Hur S, Li D, Ganz P, Deeks SG, Hsue PY. Role of T-Cell Dysfunction, Inflammation, and Coagulation in Microvascular Disease in HIV. 2016. PMID: 27998918


  55. Hsu DC, Ma YF, Hur S, Li D, Rupert A, Scherzer R, Kalapus SC, Deeks S, Sereti I, Hsue PY. Plasma IL-6 levels are independently associated with atherosclerosis and mortality in HIV-infected individuals on suppressive antiretroviral therapy. 2016. PMID: 27177313


  56. Bertero T, Oldham WM, Cottrill KA, Pisano S, Vanderpool RR, Yu Q, Zhao J, Tai Y, Tang Y, Zhang YY, Rehman S, Sugahara M, Qi Z, Gorcsan J, Vargas SO, Saggar R, Saggar R, Wallace WD, Ross DJ, Haley KJ, Waxman AB, Parikh VN, De Marco T, Hsue PY, Morris A, Simon MA, Norris KA, Gaggioli C, Loscalzo J, Fessel J, Chan SY. Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension. Volume 126 of Issue 9. 2016. PMID: 27548520


  57. Stein JH, Hsue PY. Inflammation and Arterial Injury in Individuals With Human Immunodeficiency Virus Infection. Volume 1 of Issue 4. 2016. PMID: 27438326


  58. Ramirez CM, Sinclair E, Epling L, Lee SA, Jain V, Hsue PY, Hatano H, Conn D, Hecht FM, Martin JN, McCune JM, Deeks SG, Hunt PW. Immunologic profiles distinguish aviremic HIV-infected adults. Volume 30 of Issue 10. 2016. PMID: 26854811


  59. Kohli P, Ganz P, Ma Y, Scherzer R, Hur S, Weigel B, Grunfeld C, Deeks S, Wasserman S, Scott R, Hsue PY. HIV and Hepatitis C-Coinfected Patients Have Lower Low-Density Lipoprotein Cholesterol Despite Higher Proprotein Convertase Subtilisin Kexin 9 (PCSK9): An Apparent "PCSK9-Lipid Paradox". Volume 5 of Issue 5. 2016. PMID: 27130349


  60. Waters DD, Hsue PY, Bangalore S. PCSK9 Inhibitors for Statin Intolerance? Volume 315 of Issue 15. 2016. PMID: 27039138


  61. Hsue PY, Tawakol A. Inflammation and Fibrosis in HIV: Getting to the Heart of the Matter. Volume 9 of Issue 3. 2016. PMID: 26951604


  62. Parikh RV, Ma Y, Scherzer R, Heringer AS, Macgregor JS, Martin JN, Deeks SG, Ganz P, Hsue PY. Endothelin-1 Predicts Hemodynamically Assessed Pulmonary Arterial Hypertension in HIV Infection. 2016. PMID: 26752193


  63. Chow FC, Boscardin WJ, Mills C, Ko N, Carroll C, Price RW, Deeks S, Sorond FA, Hsue PY. Cerebral vasoreactivity is impaired in treated, virally suppressed HIV-infected individuals. 2016. PMID: 26372478


  64. Feinstein MJ, Bahiru E, Achenbach C, Longenecker CT, Hsue P, So-Armah K, Freiberg MS, Lloyd-Jones DM. Patterns of Cardiovascular Mortality for HIV-Infected Adults in the United States: 1999 to 2013. Volume 117 of Issue 2. 2015. PMID: 26639041


  65. Parikh VN, Park J, Nikolic I, Channick R, Yu PB, De Marco T, Hsue PY, Chan SY. Brief Report: Coordinated Modulation of Circulating miR-21 in HIV, HIV-Associated Pulmonary Arterial Hypertension, and HIV/Hepatitis C Virus Coinfection. Volume 70 of Issue 3. 2015. PMID: 26473639


  66. Secemsky EA, Scherzer R, Nitta E, Wu AH, Lange DC, Deeks SG, Martin JN, Snider J, Ganz P, Hsue PY. Novel Biomarkers of Cardiac Stress, Cardiovascular Dysfunction, and Outcomes in HIV-Infected Individuals. 2015. PMID: 26164679


  67. Lange DC, Glidden D, Secemsky EA, Ordovas K, Deeks SG, Martin JN, Bolger AF, Hsue PY. Mitral Annular and Coronary Artery Calcification Are Associated with Mortality in HIV-Infected Individuals. 2015. PMID: 26132465


  68. Waters DD, Hsue PY. PCSK9 Inhibition to Lower LDL-Cholesterol and Reduce Cardiovascular Risk: Great Expectations. Volume 116 of Issue 10. 2015. PMID: 25953922


  69. Waldo SW, Brenner DA, McCabe JM, De la Cruz M, Long B, Narla VA, Park J, Kulkarni A, Sinclair E, Chan SY, Schick SF, Malik N, Ganz P, Hsue PY. Correction: A novel minimally-invasive method to sample human endothelial cells for molecular profiling. Volume 10 of Issue 5. 2015. PMID: 25938419


  70. Waldo SW, Brenner DA, McCabe JM, Dela Cruz M, Long B, Narla VA, Park J, Kulkarni A, Sinclair E, Chan SY, Schick SF, Malik N, Ganz P, Hsue PY. A novel minimally-invasive method to sample human endothelial cells for molecular profiling. Volume 10 of Issue 2. 2015. PMID: 25679506


  71. Somsouk M, Dunham RM, Cohen M, Albright R, Abdel-Mohsen M, Liegler T, Lifson J, Piatak M, Gorelick R, Huang Y, Wu Y, Hsue PY, Martin JN, Deeks SG, McCune JM, Hunt PW. The immunologic effects of mesalamine in treated HIV-infected individuals with incomplete CD4+ T cell recovery: a randomized crossover trial. Volume 9 of Issue 12. 2014. PMID: 25545673


  72. Hsue PY, Bittner VA, Betteridge J, Fayyad R, Laskey R, Wenger NK, Waters DD. Impact of female sex on lipid lowering, clinical outcomes, and adverse effects in atorvastatin trials. Volume 115 of Issue 4. 2014. PMID: 25637322


  73. Chow FC, Bacchetti P, Kim AS, Price RW, Hsue PY. Effect of CD4+ cell count and viral suppression on risk of ischemic stroke in HIV infection. Volume 28 of Issue 17. 2014. PMID: 25160935


  74. Hsue PY, Scherzer R, Grunfeld C, Imboden J, Wu Y, Del Puerto G, Nitta E, Shigenaga J, Schnell Heringer A, Ganz P, Graf J. Depletion of B-cells with rituximab improves endothelial function and reduces inflammation among individuals with rheumatoid arthritis. Volume 3 of Issue 5. 2014. PMID: 25336464


  75. Crane HM, Heckbert SR, Drozd DR, Budoff MJ, Delaney JA, Rodriguez C, Paramsothy P, Lober WB, Burkholder G, Willig JH, Mugavero MJ, Mathews WC, Crane PK, Moore RD, Napravnik S, Eron JJ, Hunt P, Geng E, Hsue P, Barnes GS, McReynolds J, Peter I, Grunfeld C, Saag MS, Kitahata MM. The authors reply. Volume 180 of Issue 4. 2014. PMID: 24989243


  76. Serrano-Villar S, Sainz T, Lee SA, Hunt PW, Sinclair E, Shacklett BL, Ferre AL, Hayes TL, Somsouk M, Hsue PY, Van Natta ML, Meinert CL, Lederman MM, Hatano H, Jain V, Huang Y, Hecht FM, Martin JN, McCune JM, Moreno S, Deeks SG. HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality. Volume 10 of Issue 5. 2014. PMID: 24831517


  77. Stein JH, Currier JS, Hsue PY. Arterial disease in patients with human immunodeficiency virus infection: what has imaging taught us? Volume 7 of Issue 5. 2014. PMID: 24831212


  78. Crane HM, Heckbert SR, Drozd DR, Budoff MJ, Delaney JA, Rodriguez C, Paramsothy P, Lober WB, Burkholder G, Willig JH, Mugavero MJ, Mathews WC, Crane PK, Moore RD, Napravnik S, Eron JJ, Hunt P, Geng E, Hsue P, Barnes GS, McReynolds J, Peter I, Grunfeld C, Saag MS, Kitahata MM. Lessons learned from the design and implementation of myocardial infarction adjudication tailored for HIV clinical cohorts. Volume 179 of Issue 8. 2014. PMID: 24618065


  79. Lee SA, Sinclair E, Hatano H, Hsue PY, Epling L, Hecht FM, Bangsberg DR, Martin JN, McCune JM, Deeks SG, Hunt PW. Impact of HIV on CD8+ T cell CD57 expression is distinct from that of CMV and aging. Volume 9 of Issue 2. 2014. PMID: 24586783


  80. Parikh RV, Scherzer R, Nitta EM, Leone A, Hur S, Mistry V, Macgregor JS, Martin JN, Deeks SG, Ganz P, Hsue PY. Increased levels of asymmetric dimethylarginine are associated with pulmonary arterial hypertension in HIV infection. 2014. PMID: 24469026


  81. Moyers BS, Secemsky EA, Vittinghoff E, Wong JK, Havlir DV, Hsue PY, Tseng ZH. Effect of left ventricular dysfunction and viral load on risk of sudden cardiac death in patients with human immunodeficiency virus. Volume 113 of Issue 7. 2014. PMID: 24521717


  82. Hatano H, Bacchetti P, Hsue PY, Deeks SG. Reply to Karch et al. 2014. PMID: 24421253


  83. McCabe JM, Armstrong EJ, Ku I, Kulkarni A, Hoffmayer KS, Bhave PD, Waldo SW, Hsue P, Stein JC, Marcus GM, Kinlay S, Ganz P. Physician accuracy in interpreting potential ST-segment elevation myocardial infarction electrocardiograms. 2013. PMID: 24096575


  84. Armah KA, Chang CC, Baker JV, Ramachandran VS, Budoff MJ, Crane HM, Gibert CL, Goetz MB, Leaf DA, McGinnis KA, Oursler KK, Rimland D, Rodriguez-Barradas MC, Sico JJ, Warner AL, Hsue PY, Kuller LH, Justice AC, Freiberg MS. Prehypertension, hypertension, and the risk of acute myocardial infarction in HIV-infected and -uninfected veterans. Volume 58 of Issue 1. 2013. PMID: 24065316


  85. Turner TE, Waldo SW, Kulkarni A, Armstrong EJ, Hoffmayer KS, Kinlay S, Hsue P, Ganz P, McCabe JM. Long-term outcomes of patients sent emergently to the catheterization laboratory for possible primary percutaneous coronary intervention. Volume 112 of Issue 11. 2013. PMID: 24063836


  86. Hatano H, Strain MC, Scherzer R, Bacchetti P, Wentworth D, Hoh R, Martin JN, McCune JM, Neaton JD, Tracy RP, Hsue PY, Richman DD, Deeks SG. Increase in 2-long terminal repeat circles and decrease in D-dimer after raltegravir intensification in patients with treated HIV infection: a randomized, placebo-controlled trial. 2013. PMID: 23975885


  87. Waldo SW, Armstrong EJ, Kulkarni A, Hoffmayer KS, Hsue P, Ganz P, McCabe JM. Clinical characteristics and reperfusion times among patients with an isolated posterior myocardial infarction. Volume 25 of Issue 8. 2013. PMID: 23913600


  88. Brenner DA, Dela Cruz M, Thomas K, McCabe JM, Ganz P, Hsue PY, Waldo SW. Emergency medical service utilization and door-to-balloon time for HIV-infected individuals with ST-elevation myocardial infarction. Volume 168 of Issue 5. 2013. PMID: 23871355


  89. Ganz P, Hsue PY. Endothelial dysfunction in coronary heart disease is more than a systemic process. Volume 34 of Issue 27. 2013. PMID: 23756335


  90. Parikh RV, Scherzer R, Grunfeld C, Nitta EM, Leone A, Martin JN, Deeks SG, Ganz P, Hsue PY. Elevated levels of asymmetric dimethylarginine are associated with lower CD4+ count and higher viral load in HIV-infected individuals. Volume 229 of Issue 1. 2013. PMID: 23711612


  91. Barnett CF, Hsue PY. Human immunodeficiency virus-associated pulmonary arterial hypertension. Volume 34 of Issue 2. 2013. PMID: 23702177


  92. Hsu JC, Li Y, Marcus GM, Hsue PY, Scherzer R, Grunfeld C, Shlipak MG. Atrial fibrillation and atrial flutter in human immunodeficiency virus-infected persons: incidence, risk factors, and association with markers of HIV disease severity. Volume 61 of Issue 22. 2013. PMID: 23563125


  93. Waldo SW, Armstrong EJ, Kulkarni A, Hoffmayer K, Kinlay S, Hsue P, Ganz P, McCabe JM. Comparison of clinical characteristics and outcomes of cardiac arrest survivors having versus not having coronary angiography. Volume 111 of Issue 9. 2013. PMID: 23391104


  94. Tseng ZH, Moyers B, Secemsky EA, Havlir DV, Hsue PY. PR Interval and sudden cardiac death in patients with HIV infection. Volume 207 of Issue 1. 2012. PMID: 23186784


  95. Hatano H, Scherzer R, Wu Y, Harvill K, Maka K, Hoh R, Sinclair E, Palmer S, Martin JN, Busch MP, Deeks SG, Hsue PY. A randomized controlled trial assessing the effects of raltegravir intensification on endothelial function in treated HIV infection. Volume 61 of Issue 3. 2012. PMID: 22918156


  96. Selby VN, Scherzer R, Barnett CF, MacGregor JS, Morelli J, Donovan C, Deeks SG, Martin JN, Hsue PY. Doppler echocardiography does not accurately estimate pulmonary artery systolic pressure in HIV-infected patients. 2012. PMID: 22781217


  97. Stein JH, Hsue PY. Inflammation, immune activation, and CVD risk in individuals with HIV infection. Volume 308 of Issue 4. 2012. PMID: 22820794


  98. McCabe JM, Armstrong EJ, Kulkarni A, Hoffmayer KS, Bhave PD, Garg S, Patel A, MacGregor JS, Hsue P, Stein JC, Kinlay S, Ganz P. Prevalence and factors associated with false-positive ST-segment elevation myocardial infarction diagnoses at primary percutaneous coronary intervention–capable centers: a report from the Activate-SF registry. 2012. PMID: 22566489


  99. Hsue PY, Deeks SG, Hunt PW. Immunologic basis of cardiovascular disease in HIV-infected adults. Volume 205 Suppl 3. 2012. PMID: 22577211


  100. Ho JE, Scherzer R, Hecht FM, Maka K, Selby V, Martin JN, Ganz P, Deeks SG, Hsue PY. The association of CD4+ T-cell counts and cardiovascular risk in treated HIV disease. 2012. PMID: 22382147


  101. Tseng ZH, Secemsky EA, Dowdy D, Vittinghoff E, Moyers B, Wong JK, Havlir DV, Hsue PY. Sudden cardiac death in patients with human immunodeficiency virus infection. Volume 59 of Issue 21. 2012. PMID: 22595409


  102. Frey PF, Ganz P, Hsue PY, Benowitz NL, Glantz SA, Balmes JR, Schick SF. The exposure-dependent effects of aged secondhand smoke on endothelial function. Volume 59 of Issue 21. 2012. PMID: 22595411


  103. Sacre K, Hunt PW, Hsue PY, Maidji E, Martin JN, Deeks SG, Autran B, McCune JM. A role for cytomegalovirus-specific CD4+CX3CR1+ T cells and cytomegalovirus-induced T-cell immunopathology in HIV-associated atherosclerosis. Volume 26 of Issue 7. 2012. PMID: 22313962


  104. Hsue PY, Scherzer R, Hunt PW, Schnell A, Bolger AF, Kalapus SC, Maka K, Martin JN, Ganz P, Deeks SG. Carotid Intima-Media Thickness Progression in HIV-Infected Adults Occurs Preferentially at the Carotid Bifurcation and Is Predicted by Inflammation. Volume 1 of Issue 2. 2012. PMID: 23130122


  105. Armstrong EJ, Kulkarni AR, Hoffmayer KS, Bhave PD, MacGregor JS, Hsue P, Stein JC, Kinlay S, Ganz P, McCabe JM. Delaying primary percutaneous coronary intervention for computed tomographic scans in the emergency department. 2012. PMID: 22534052


  106. Hsue PY, Scherzer R, Grunfeld C, Nordstrom SM, Schnell A, Kohl LP, Nitta E, Martin JN, Deeks SG, Weiss EJ. HIV infection is associated with decreased thrombin generation. Volume 54 of Issue 8. 2012. PMID: 22438347


  107. Almodovar S, Knight R, Allshouse AA, Roemer S, Lozupone C, McDonald D, Widmann J, Voelkel NF, Shelton RJ, Suarez EB, Hammer KW, Goujard C, Petrosillo N, Simonneau G, Hsue PY, Humbert M, Flores SC. Human Immunodeficiency Virus nef signature sequences are associated with pulmonary hypertension. Volume 28 of Issue 6. 2012. PMID: 22066947


  108. Papasavvas E, Hsue P, Reynolds G, Pistilli M, Hancock A, Martin JN, Deeks SG, Montaner LJ. Increased CD34+/KDR+ cells are not associated with carotid artery intima-media thickness progression in chronic HIV-positive subjects. 2011. PMID: 22300770


  109. Hsue PY, Ordovas K, Lee T, Reddy G, Gotway M, Schnell A, Ho JE, Selby V, Madden E, Martin JN, Deeks SG, Ganz P, Waters DD. Carotid intima-media thickness among human immunodeficiency virus-infected patients without coronary calcium. 2011. PMID: 22169125


  110. Secemsky EA, Lange D, Ho JE, Brayton K, Ganz PA, Farr G, Macgregor JS, Hsue PY. Improvement in revascularization time after creation of a coronary catheterization laboratory at a public hospital. 2011. PMID: 22123753


  111. Secemsky E, Lange D, Waters DD, Goldschlager NF, Hsue PY. Hemodynamic and arrhythmogenic effects of cocaine in hypertensive individuals. Volume 13 of Issue 10. 2011. PMID: 21974762


  112. Hsue PY, Bolger AF, Martin JN. Pulmonary hypertension in HIV-infected individuals. Volume 53 of Issue 1. 2011. PMID: 21653312


  113. Almodovar S, Hsue PY, Morelli J, Huang L, Flores SC. Pathogenesis of HIV-associated pulmonary hypertension: potential role of HIV-1 Nef. 2011. PMID: 21653533


  114. Choi AI, Lo JC, Mulligan K, Schnell A, Kalapus SC, Li Y, Hunt PW, Martin JN, Deeks SG, Hsue PY. Association of vitamin D insufficiency with carotid intima-media thickness in HIV-infected persons. Volume 52 of Issue 7. 2011. PMID: 21273298


  115. Worm SW, Hsue P. Role of biomarkers in predicting CVD risk in the setting of HIV infection? Volume 5 of Issue 6. 2010. PMID: 20978389


  116. Rangel C, Shu RG, Lazar LD, Vittinghoff E, Hsue PY, Marcus GM. Beta-blockers for chest pain associated with recent cocaine use. 2010. PMID: 20498415


  117. Naeger DM, Martin JN, Sinclair E, Hunt PW, Bangsberg DR, Hecht F, Hsue P, McCune JM, Deeks SG. Cytomegalovirus-specific T cells persist at very high levels during long-term antiretroviral treatment of HIV disease. Volume 5 of Issue 1. 2010. PMID: 20126452


  118. Hsue PY, Hunt PW, Ho JE, Farah HH, Schnell A, Hoh R, Martin JN, Deeks SG, Bolger AF. Impact of HIV infection on diastolic function and left ventricular mass. Volume 3 of Issue 1. 2009. PMID: 19933410


  119. Ganz P, Hsue PY. Assessment of structural disease in the coronary microvasculature. Volume 120 of Issue 16. 2009. PMID: 19805646


  120. Hsue PY, Hunt PW, Wu Y, Schnell A, Ho JE, Hatano H, Xie Y, Martin JN, Ganz P, Deeks SG. Association of abacavir and impaired endothelial function in treated and suppressed HIV-infected patients. Volume 23 of Issue 15. 2009. PMID: 19542863


  121. Ho JE, Hsue PY. Cardiovascular manifestations of HIV infection. Volume 95 of Issue 14. 2009. PMID: 19564432


  122. Ganz P, Ho JE, Hsue PY. Structural and functional manifestations of human atherosclerosis: do they run in parallel? Volume 30 of Issue 13. 2009. PMID: 19502231


  123. Hsue PY, Hunt PW, Schnell A, Kalapus SC, Hoh R, Ganz P, Martin JN, Deeks SG. Role of viral replication, antiretroviral therapy, and immunodeficiency in HIV-associated atherosclerosis. Volume 23 of Issue 9. 2009. PMID: 19390417


  124. Ku IA, Imboden JB, Hsue PY, Ganz P. Rheumatoid arthritis: model of systemic inflammation driving atherosclerosis. 2009. PMID: 19430165


  125. Hlatky MA, Greenland P, Arnett DK, Ballantyne CM, Criqui MH, Elkind MS, Go AS, Harrell FE, Hong Y, Howard BV, Howard VJ, Hsue PY, Kramer CM, McConnell JP, Normand SL, O'Donnell CJ, Smith SC, Wilson PW. Criteria for evaluation of novel markers of cardiovascular risk: a scientific statement from the American Heart Association. Volume 119 of Issue 17. 2009. PMID: 19364974


  126. Wohl DA, Waters D, Simpson RJ, Richard S, Schnell A, Napravnik S, Keys J, Eron JJ, Hsue P. Ezetimibe alone reduces low-density lipoprotein cholesterol in HIV-infected patients receiving combination antiretroviral therapy. Volume 47 of Issue 8. 2008. PMID: 18781882


  127. Hsue PY, Squires K, Bolger AF, Capili B, Mensah GA, Temesgen Z, Wanke CA, Wohl DA. Screening and assessment of coronary heart disease in HIV-infected patients. Volume 118 of Issue 2. 2008. PMID: 18566317


  128. Grinspoon SK, Grunfeld C, Kotler DP, Currier JS, Lundgren JD, Dubé MP, Lipshultz SE, Hsue PY, Squires K, Schambelan M, Wilson PW, Yarasheski KE, Hadigan CM, Stein JH, Eckel RH. State of the science conference: Initiative to decrease cardiovascular risk and increase quality of care for patients living with HIV/AIDS: executive summary. Volume 118 of Issue 2. 2008. PMID: 18566320


  129. Hsue PY, Deeks SG, Farah HH, Palav S, Ahmed SY, Schnell A, Ellman AB, Huang L, Dollard SC, Martin JN. Role of HIV and human herpesvirus-8 infection in pulmonary arterial hypertension. 2008. PMID: 18427200


  130. McCord J, Jneid H, Hollander JE, de Lemos JA, Cercek B, Hsue P, Gibler WB, Ohman EM, Drew B, Philippides G, Newby LK. Management of cocaine-associated chest pain and myocardial infarction: a scientific statement from the American Heart Association Acute Cardiac Care Committee of the Council on Clinical Cardiology. Volume 117 of Issue 14. 2008. PMID: 18347214


  131. Barnett CF, Hsue PY, Machado RF. Pulmonary hypertension: an increasingly recognized complication of hereditary hemolytic anemias and HIV infection. Volume 299 of Issue 3. 2008. PMID: 18212317


  132. Hunt PW, Brenchley J, Sinclair E, McCune JM, Roland M, Page-Shafer K, Hsue P, Emu B, Krone M, Lampiris H, Douek D, Martin JN, Deeks SG. Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapy. Volume 197 of Issue 1. 2008. PMID: 18171295


  133. Hsue PY, McManus D, Selby V, Ren X, Pillutla P, Younes N, Goldschlager N, Waters DD. Cardiac arrest in patients who smoke crack cocaine. 2007. PMID: 17350374


  134. Hsue PY, Hunt PW, Sinclair E, Bredt B, Franklin A, Killian M, Hoh R, Martin JN, McCune JM, Waters DD, Deeks SG. Increased carotid intima-media thickness in HIV patients is associated with increased cytomegalovirus-specific T-cell responses. Volume 20 of Issue 18. 2006. PMID: 17117013


  135. Hsue PY, Waters DD. What a cardiologist needs to know about patients with human immunodeficiency virus infection. Volume 112 of Issue 25. 2005. PMID: 16365213


  136. Emu B, Sinclair E, Favre D, Moretto WJ, Hsue P, Hoh R, Martin JN, Nixon DF, McCune JM, Deeks SG. Phenotypic, functional, and kinetic parameters associated with apparent T-cell control of human immunodeficiency virus replication in individuals with and without antiretroviral treatment. Volume 79 of Issue 22. 2005. PMID: 16254352


  137. Saigo M, Hsue PY, Waters DD. Role of thrombotic and fibrinolytic factors in acute coronary syndromes. Volume 46 of Issue 6. 2004. PMID: 15224258


  138. Hsue PY, Lo JC, Franklin A, Bolger AF, Martin JN, Deeks SG, Waters DD. Progression of atherosclerosis as assessed by carotid intima-media thickness in patients with HIV infection. 2004. PMID: 15023877


  139. Hsue PY, Giri K, Erickson S, MacGregor JS, Younes N, Shergill A, Waters DD. Clinical features of acute coronary syndromes in patients with human immunodeficiency virus infection. Volume 109 of Issue 3. 2004. PMID: 14718406


  140. Hsue PY, Salinas CL, Bolger AF, Benowitz NL, Waters DD. Acute aortic dissection related to crack cocaine. 2002. PMID: 11927528


  141. Waters DD, Hsue PY. What is the role of intensive cholesterol lowering in the treatment of acute coronary syndromes? Volume 88 of Issue 7B. 2001. PMID: 11595193


  142. Sun ZY, Truong HT, Pratt EA, Sutherland DC, Kulig CE, Homer RJ, Groetsch SM, Hsue PY, Ho C. A 19F-NMR study of the membrane-binding region of D-lactate dehydrogenase of Escherichia coli. Volume 2 of Issue 11. 1993. PMID: 8268803